Mn/S diatomic sites in CN to enhance O activation for photocatalytic elimination of emerging pollutants.

Oxygen activation leading to the generation of reactive oxygen species (ROS) is essential for photocatalytic environmental remediation. The limited efficiency of O adsorption and reductive activation significantly limits the production of ROS when employing CN for the degradation of emerging pollutants. Doping with metal single atoms may lead to unsatisfactory efficiency, due to the recombination of photogenerated electron-hole pairs.

Heterothermic Cataluminescence Sensor System for Efficient Determination of Aldehyde Molecules.

A simple and stable cataluminescence (CTL) sensing platform based on a single sensing material for effective and rapid detection of aldehydes is an urgent need due to growing concerns for the environment, security, and health. Here, an effective and user-friendly identification method is successfully proposed to determine six common aldehydes of homologous compounds via a heterothermic CTL sensor system. Using GdO with excellent catalytic activity as a sensing material, thermodynamic and kinetic insights into the interactions between GdO and aldehydes at different temperatures were extracted and integrated to generate a unique constellation profile for each tested aldehyde, whereby achieving their effective and prompt determination.

Effects of PM exposure on clock gene and cell cycle in human umbilical vein endothelial cells.

Background: Fine particulate matter (PM) exposure has been closely associated with cardiovascular diseases, which are relevant to cell cycle arrest. Brain and muscle aryl-hydrocarbon receptor nuclear translocator-like protein 1 (BMAL1) not only participates in regulating the circadian clock but also plays a role in modulating cell cycle. However, the precise contribution of the circadian clock gene to PM-induced cell cycle change remains unclear.

Unexpectedly high thermal stability of Au nanotriangle@mSiO yolk-shell nanoparticles.

The shape of Au nanoparticles (NPs) plays a crucial role for applications in, amongst others, catalysis, electronic devices, biomedicine, and sensing. Typically, the deformation of the morphology of Au NPs is the most significant cause of loss of functionality. Here, we systematically investigate the thermal stability of Au nanotriangles (NTs) coated with (mesoporous) silica shells with different morphologies (core-shell (CS): Au NT@mSiO/yolk-shell (YS): Au NT@mSiO) and compare these to 'bare' nanoparticles (Au NTs), by a combination of and/or TEM techniques and spectroscopy methods.

Integrated Optimization of Crystal Facets and Nanoscale Spatial Confinement toward the Boosted Catalytic Performance of Pd Nanocrystals.

Tuning the surface chemical property and the local environment of nanocrystals is crucial for realizing a high catalytic performance in various reactions. Herein, we aim to elucidate the structure sensitivity of Pd facets on the surface catalytic hydrogenation reaction and to identify what role the nanoconfinement effect plays in the catalytic properties of Pd nanocrystal catalysts. By controlling the coating structures of mesoporous silica (mSiO) on Pd nanocrystals with different exposed facets that include {100}, {111}, and {}, we present a series of Pd@mSiO nanoreactors in core-shell and yolk-shell structures and the discovery of a partial-coated structure, which can provide different types of nanoconfinement, and we propose a seed size-dominated growth mechanism.

Morphology-Controlled Growth of Crystalline Ag-Pt-Alloyed Shells onto Au Nanotriangles and Their Plasmonic Properties.

The surface plasmon resonance of noble-metal nanoparticles depends on nanoscale size, morphology, and composition, and provides great opportunities for applications in biomedicine, optoelectronics, (photo)catalysis, photovoltaics, and sensing. Here, we present the results of synthesizing ternary metallic or trimetallic nanoparticles, Au nanotriangles (Au NTs) with crystalline Ag-Pt alloyed shells, the morphology of which can be adjusted from a yolk-shell to a core-shell structure by changing the concentration of AgNO or the concentration of Au NT seeds, while the shell thickness can be precisely controlled by adjusting the concentration of KPtCl. By monitoring the growth process with UV-vis spectra and scanning transmission electron microscopy (STEM), the shells on the Au NT-Ag-Pt yolk-shell nanoparticles were found to grow via a galvanic replacement synergistic route.

24-Hour efficacy of single primary selective laser trabeculoplasty versus latanoprost eye drops for Naïve primary open-angle glaucoma and ocular hypertension patients.

This prospective, observer-masked, randomized clinical trial was conducted between December 2018 and June 2021 at Eye Hospital, China Academy of Chinese Medical Sciences. A total of 45 glaucoma patients from Beijing, China, were enrolled in this clinical trial to compare the short-term efficacy of primary single-selective laser trabeculoplasty (SLT) to 0.005% latanoprost eye drops for the treatment of 24-h intraocular pressure (IOP) in patients with newly diagnosed primary open angle glaucoma (POAG) and ocular hypertension (OHT).

Instant Fingerprint Discrimination for Military Explosive Vapors by Dy Doping a LaO-Based Cataluminescence Sensor System.

With the intensification of explosive-based terrorism attack and environmental concerns, the innovation of high-efficiency and portable sensors for facile, rapid, and reliable monitoring of explosives has become one of the major demands in societies. Herein, a reliable and easy-to-use cataluminescence sensor system based on Dy doping LaO nanorod catalysts has been developed for the identification and detection of six types of military explosive vapors, including homologous compounds and even isomers. The efficient discrimination is to make full use of the thermodynamic and kinetic information that can be extracted from the catalytic oxidation process of explosive molecules on various sensing materials, that is, the response signal and response time to generate the fingerprint of each target compound, while the rapid detection of the strategy can be manifested in response toward six military explosive vapors within 2.

Predicting Kirsten Rat Sarcoma Virus Gene Mutation Status in Patients With Colorectal Cancer by Radiomics Models Based on Multiphasic CT.

Objective: To develop and validate radiomics models based on multiphasic CT in predicting Kirsten rat sarcoma virus (KRAS) gene mutation status in patients with colorectal cancer (CRC).

Materials And Methods: A total of 231 patients with pathologically confirmed CRC were retrospectively enrolled and randomly divided into training(n=184) and test groups(n=47) in a ratio of 4:1. A total of 1316 quantitative radiomics features were extracted from non-contrast phase (NCP), arterial-phase (AP) and venous-phase (VP) CT for each patient.

Tandem catalysis with double-shelled hollow spheres.

Metal-zeolite composites with metal (oxide) and acid sites are promising catalysts for integrating multiple reactions in tandem to produce a wide variety of wanted products without separating or purifying the intermediates. However, the conventional design of such materials often leads to uncontrolled and non-ideal spatial distributions of the metal inside/on the zeolites, limiting their catalytic performance. Here we demonstrate a simple strategy for synthesizing double-shelled, contiguous metal oxide@zeolite hollow spheres (denoted as MO@ZEO DSHSs) with controllable structural parameters and chemical compositions.

Deciphering the Core Metabolites of Fanconi Anemia by Using a Multi-Omics Composite Network.

Deciphering the metabolites of human diseases is an important objective of biomedical research. Here, we aimed to capture the core metabolites of Fanconi anemia (FA) using the bioinformatics method of a multi-omics composite network. Based on the assumption that metabolite levels can directly mirror the physiological state of the human body, we used a multi-omics composite network that integrates six types of interactions in humans (gene-gene, disease phenotype-phenotype, disease-related metabolite-metabolite, gene-phenotype, gene-metabolite, and metabolite-phenotype) to procure the core metabolites of FA.

Intravoxel Incoherent Motion Diffusion-Weighted Imaging for Predicting and Monitoring the Response of Anti-Angiogenic Treatment in the Orthotopic Nude Mouse Model of Lung Adenocarcinoma.

Background: The treatment efficacy of angiogenesis inhibitor could be underestimated at an early stage based on tumor volume changes. Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) can quantitatively assess tumors at the cellular level, but it is unclear whether it can provide useful information for assessing treatment response of anti-angiogenic treatment for lung adenocarcinoma.

Purpose: To determine the use of IVIM-DWI for non-invasive monitoring of the early response to anti-angiogenic treatment in the orthotopic transplantation of lung adenocarcinoma model.

Evaluation of peripheral nerve acute crush injury in rabbits: comparison among diffusion kurtosis imaging, diffusion tensor imaging and electromyography.

Objective: Diffusion kurtosis imaging (DKI) has been proven to provide additional value for assessing many central nervous system diseases compared with conventional diffusion tensor imaging (DTI); however, whether it has the same value in peripheral nerve injury is unclear. This study aimed to investigate the performance of DKI, DTI, and electromyography (EMG) in evaluating peripheral nerve crush injury (PNCI) in rabbits.

Materials And Methods: A total of 27 New Zealand white rabbits were selected to establish a PNCI model.

Single-step coating of mesoporous SiO onto nanoparticles: growth of yolk-shell structures from core-shell structures.

Yolk-shell nanoparticles based on mesoporous SiO (mSiO) coating of Au nanoparticles (Au NPs) hold great promise for many applications in e.g., catalysis, biomedicine, and sensing.

Assessing accommodative presbyopic biometric changes of the entire anterior segment using single swept-source OCT image acquisitions.

Background/objectives: To evaluate biometric changes throughout the anterior chamber during accommodation and presbyopia using single image acquisition swept-source anterior-segment optical coherence tomography (AS-OCT).

Subject/methods: Anterior-segment images were obtained using a new swept-source AS-OCT device (ANTERION, Heidelberg Engineering) from healthy volunteers (n = 71) across two centers in this prospective observational case series. In one image acquisition, cornea through posterior lens, including the ciliary muscle on both sides of the right eye, was imaged.

Clinical characteristics, rates of blindness, and geographic features of PACD in China.

Objective: To analyze the rates of blindness with the demographics and clinical characteristics of patients with primary angle-closure disease (PACD) to provide a comprehensive epidemiologic reference in China.

Methods: A retrospective analysis was conducted in the Chinese Glaucoma Study Consortium database, which is a national multicenter glaucoma research alliance of 111 hospitals participating between December 21, 2015 and September 9, 2018. The diagnosis of PACD was made by qualified physicians through examination.

Symmetric and asymmetric epitaxial growth of metals (Ag, Pd, and Pt) onto Au nanotriangles: effects of reductants and plasmonic properties.

The surface plasmon resonance of noble metals can be tuned by morphology and composition, offering interesting opportunities for applications in biomedicine, optoelectronics, photocatalysis, photovoltaics, and sensing. Here, we present the results of the symmetrical and asymmetrical overgrowth of metals (Ag, Pd, and Pt) onto triangular Au nanoplates using l-ascorbic acid (AA) and/or salicylic acid (SA) as reductants. By varying the reaction conditions, various types of Au nanotriangle-metal (Au NT-M) hetero-nanostructures were easily prepared.

Age- and refraction-related changes in anterior segment anatomical structures measured by swept-source anterior segment OCT.

Purpose: To assess the effects of age and refractive status on anterior segment anatomical structures, including the ciliary body, using a new swept-source anterior segment optical coherence tomography (AS-OCT) device.

Methods: This prospective observational study included 63 healthy volunteers (mean age: 44.2 years).

CircCFL1/MiR-107 Axis Targeting HMGB1 Promotes the Malignant Progression of Diffuse Large B-Cell Lymphoma Tumors.

Objective: The pathogenesis of diffuse large B-cell lymphoma (DLBCL) has not yet been fully elucidated. An increasing number of studies have shown that circular RNAs (circRNAs) play an important role in tumorigenesis and development. The aim of this study was to investigate the effect of CircCFL1 on the malignant progression of DLBCL.