To develop Monte Carlo simulations to predict the relationship of with liver fat content at 1.5 T and 3.0 T.
View Article and Find Full Text PDFPurpose: To investigate the effect of particle size on liver by Monte Carlo simulation and phantom studies at both 1.5 T and 3.0 T.
View Article and Find Full Text PDFComput Methods Programs Biomed
May 2023
Background And Objective: To model hepatic steatosis in adult humans with non-alcoholic fatty liver disease based on stereology and spatial distribution of fat droplets from liver biopsy specimens.
Methods: Histological analysis was performed on 30 adult human liver biopsy specimens with varying degrees of steatosis. Morphological features of fat droplets were characterized by gamma distribution function (GDF) in both two-dimensional (2D) and three-dimensional (3D) spaces from three aspects: 1) size distribution indicating non-uniformity of fat droplets in radius; 2) nearest neighbor distance distribution indicating heterogeneous accumulation (i.