Morbidity, Mortality, and Epidemiological Features of Clinical Invasive Listeriosis Isolates from Sentinel Surveillance in Beijing, China, 2013-2022.

Listeriosis is a relatively rare but severe foodborne disease, which has significant public health concern of persons with underlying conditions and pregnant women. This study aimed to estimate the morbidity, mortality, and fatality rates of listeriosis over a 10-year period and clarify the epidemiological features of the pathogen in Beijing, China, based on voluntary reporting of sentinel surveillance. A total of 228 listeriosis cases were reported with annual morbidity rate of 1.

A Listeriosis Case Associated with Ice Cream Consumption in China in 2019.

During the 2019 Chinese National Microbiological Food Safety Surveillance program, was detected in ice cream samples produced by Manufacturer A. By comparing the sequences of isolates derived from the ice cream with those of isolates derived from humans, we identified one human-derived isolate that was genetically indistinguishable from one ice cream-derived isolates. The patient was hospitalized with listeriosis in Beijing, China in March 2019.

Prolyl 4-hydroxylase α-subunit family regulation of type I collagen deposition and IL17RB/c-Jun activation synergistically mediate choline dehydrogenase promotion of colorectal cancer metastasis.

Metastasis continues to pose a significant challenge in tumor treatment. Evidence indicates that choline dehydrogenase (CHDH) is crucial in tumorigenesis. However, the functional role of CHDH in colorectal cancer (CRC) metastasis remains unreported.

Light intensity-regulated glycogen synthesis and pollutant removal in microalgal-bacterial granular sludge for wastewater treatment.

As light intensity plays a pivotal role in the microalgal-bacterial granular sludge (MBGS) process, understanding its impact on system performance and energy dynamics is essential. This study investigated the effects of varying light intensities (20, 100, 200, and 300 μ mol/m²/s) on the performance of MBGS in urban wastewater treatment, with a particular focus on glycogen accumulation and pollutant removal. The results demonstrated that light intensity significantly influenced microbial community structure, glycogen accumulation, and pollutant removal efficiency.

Deciphering the virucidal potential of hydroxyl radical during ozonation: Implications for waterborne virus inactivation.

The heightened public health risks associated with viral contamination in water have led to a strong emphasis on effective disinfection strategies. Ozone is a potent disinfectant widely employed for the inactivation of pathogens, yet comprehensive reports detailing the virucidal efficacy of hydroxyl radical (•OH) generated during ozonation are limited. The present research meticulously deciphered the role and influencing factors of •OH during ozone disinfection processes, elucidating how •OH enhanced ozone-mediated virus inactivation from both kinetic and molecular biological perspectives.

Cytoplasmic Aggregates of Splicing Factor Proline-Glutamine Rich Disrupt Nucleocytoplasmic Transport and Induce Persistent Stress Granules.

Splicing factor proline-glutamine rich (SFPQ), a multifunctional RNA-binding protein (RBP), shows cytoplasmic colocalisation with stress granule (SG) markers; however, the causative relationship and mechanism underlying this coalescence of SFPQ aggregates and SGs remain unclear. In this study, we demonstrate that SFPQ lacking its nuclear localisation sequence spontaneously forms cytoplasmic aggregates that abnormally incorporate immature RNA and induce persistent SGs. mRNA profiling showed that SFPQ mislocalisation induced extensive changes in RNA processing, with a subset of alternatively spliced transcripts associated with nucleocytoplasmic transport.

Exploring and Validating the Mechanism of Ulinastatin in the Treatment of Sepsis-Associated Encephalopathy Based on Transcriptome Sequencing.

Purpose: Sepsis can induce sepsis-associated encephalopathy (SAE), with Ulinastatin (UTI) serving a critical anti-inflammatory role. This study aimed to identify the hub genes in an SAE mouse model following UTI intervention and investigate the underlying molecular mechanisms.

Materials And Methods: Through differential expression analysis to obtain differentially expressed genes (DEGs), ie, UTI vs CLP (DEGs1) and Con vs CLP (DEGs2).

Fluorine-free, superhydrophobic self-healing and UV-blocking cotton fabric for oil/water separation.

The discharge of oily wastewater not only pollutes waters but also deteriorates our living environment. Superhydrophobic cotton fabric is considered as an important remedy material for oily wastewater cleanup due to outstanding advantages including low cost, high porosity and switchable wettability. However, the existing superhydrophobic fabrics cannot exhibit durable superhydrophobicity during real-life applications due to poor interaction between the coatings and fabric substrates.

Correlation of higher right-wing authoritarianism and lower social dominance orientation with greater subjective well-being in China.

Background: The associations between authoritarian personality and subjective well-being remains understudied, especially in China. In addition, as Chinese individuals and Chinese organizations generally attach importance to authority, exploring the matching effect of individual authoritarian personality and organizational culture (OC) can provide information for career selection, talent recruitment and university enrollment. The present study aimed to test associations between authoritarian personality traits (right-wing authoritarian, RWA; social dominance orientation, SDO) and subjective well-being (SWB; including positive affect, PA; negative affect, NA; and life satisfaction, LS) at the general and component-specific levels and the possible moderating role of OC (military or nonmilitary universities) on the associations in Chinese culture for the first time.

Relationship Between Physical Activity and Subjective Well-Being Among College Students: The Mediating Role of Social Support.

Subjective well-being is a key concept in positive psychology and is associated with a variety of physical and mental health outcomes. Physical activity (PA) is a modifiable health behavior that has been identified as a potential correlate of subjective well-being. However, the underlying mechanisms that connect PA to subjective well-being are not well-understood.

Light Walking Patterns and Postprandial Cardiometabolic Responses in Young Obese Adults: A Randomized Crossover Study.

Context: Recent studies suggest that light-intensity physical activity may enhance cardiometabolic health and reduce mortality risk in adults. However, more information is required to understand the patterns of light-intensity physical activity and postprandial cardiometabolic health.

Objective: This study examined the effects of different light-intensity walking patterns on postprandial cardiometabolic responses in young obese adults.

Carbon-based electrocatalytic dual-membrane system bolsters singlet oxygen production for ultrafast water decontamination.

Reactive electrochemical membranes (REMs) are promising technologies in treating pharmaceuticals and personal care products (PPCPs) in water. Herein, a novel carbon-based electrocatalytic dual-membrane system was designed to exploit the whole redox process of electrodes, in which the membrane cathode and anode were formed by carbon fibers doped with Fe and metal organic frameworks derived SnO, respectively. Propranolol (PRO) was used as a representative of PPCPs.

Molecule level precise construction of donor-acceptor polymeric carbon nitride for photocatalytic hydrogen evolution.

Constructing donor-acceptor structures in polymeric carbon nitride (CN) provides an attractive pathway for facilitating charge carrier separation in photocatalytic reactions. However, achieving the implantation of donor or acceptor moieties at molecule level precision remains challenging. Here we develop a three-dimensional (3D) porous thiophene implanted carbon nitride (TCN) with donor-acceptor structure via a supramolecular assembly strategy.

Multifactorial Analysis of the Effect of Applied Gamma-Polyglutamic Acid on Soil Infiltration Characteristics.

To investigate the mechanism and influence of applying gamma-polyglutamic acid (γ-PGA) on soil water infiltration, laboratory experiments and numerical simulations were conducted using Hydrus-1D. These studies assessed the impact of various application rates of γ-PGA on soil water characteristic parameters. Orthogonal simulation experiments on soil bulk density, γ-PGA application rates, and burial depths were performed utilizing predefined soil water characteristic values (twelve groups: nine groups of numerical simulation experiments and three groups of laboratory verification tests), and the soil infiltration characteristics were analyzed.

Synergistic Effects of Time-Restricted Feeding and Resistance Training on Body Composition and Metabolic Health: A Systematic Review and Meta-Analysis.

Background: This systematic review and meta-analysis examined the synergistic impact of time-restricted feeding (TRF) combined with resistance training (RT) (TRF + RT) on body composition and metabolic health in adults, contrasting it with habitual eating patterns (CON) and RT (CON + RT).

Methods: Adhering to PRISMA guidelines, five databases were searched up to 28 April 2024. Randomized controlled trials or crossover trials assessing the effects of TRF + RT for at least 4 weeks in adults were selected.

Attitudes and preferences towards erectile dysfunction treatment among men with fertility needs: insights from a clinical study.

Erectile dysfunction (ED) is prevalent among males experiencing fertility challenges, yet attitudes towards actively treating ED in this group are under-researched. From a cohort of 1256 men with reproductive needs, 303 were identified with ED. The survey encompassed 296 respondents who correctly completed the second questionnaire, revealing that 50.

A convenient research strategy for functional verification of epigenetic regulators during spermatogenesis.

Spermatogenesis is a fundamental process that requires a tightly controlled epigenetic event in spermatogonial stem cells (SSCs). The mechanisms underlying the transition from SSCs to sperm are largely unknown. Most studies utilize gene knockout mice to explain the mechanisms.

Enhancing the performance of microalgal-bacterial systems with sodium bicarbonate: A step forward to carbon neutrality of municipal wastewater treatment.

The microalgal-bacterial granular sludge (MBGS) process, enhanced with sodium bicarbonate (NaHCO), offers a sustainable alternative for wastewater treatment aiming for carbon neutrality. This study demonstrates that NaHCO, which can be derived from the flue gases and alkaline textile wastewater, significantly enhances pollutant removal and biomass production. Optimal addition of NaHCO was found to achieve an inorganic-to-organic carbon ratio of 1.

Pre-packaged cold-chain ready-to-eat food as a source of sporadic listeriosis in Beijing, China.

Objectives: Using a sporadic case of listeriosis suspected to have been caused by consuming a pre-packaged cold-chain ready-to-eat (RTE) food in Beijing, China in 2021 as an exemplar, this study demonstrated the importance of thoroughly investigating the source of listeriosis up to the production point for mitigating infection risk during routine monitoring of Listeria in food facilities and national surveillance program using whole-genome sequencing (WGS).

Methods: Epidemiological, laboratory, traceback, and plant investigations were used to identify the source of infection.

Results: WGS showed the isolate from the patient was genetically indistinguishable from that of the implicated food.

Neglected role of iron redox cycle in direct interspecies electron transfer in anaerobic methanogenesis: Inspired from biogeochemical processes.

Anaerobic digestion is an indispensable technical option towards green and low-carbon wastewater treatment, with interspecies electron transfer (IET) playing a key role in its efficiency and operational stability. The exogenous semiconductive iron oxides have been proven to effectively enhance IET, while the cognition of the physicochemical-biochemical coupling stimulatory mechanism was circumscribed and remains to be elucidated. In this study, semiconductive iron oxides, α-FeO, γ-FeO, α-FeOOH, and γ-FeOOH were found to significantly enhance syntrophic methanogenesis by 76.