Debus-Radziszewski Reaction Inspired In Situ "One-Pot" Approach to Construct Luminescent Zirconium-Organic Frameworks.

Metal-organic frameworks have received extensive development in the past three decades, which are generally constructed via the reaction between inorganic building units and commercially available or presynthesized organic linkers. However, the presynthesis of organic linkers is usually time-consuming and unsustainable due to multiple-step separation and purification. Therefore, methodology development of a new strategy is fundamentally important for the construction and further exploration of the applications of MOFs.

A Longitudinal Dynamic Change in LMR Can Be a Biomarker for Recurrence in Fusobacterium Nucleatum-Positive Colorectal Cancer Patients.

Purpose: This study assessed lymphocyte-to-monocyte ratio (LMR) changes to predict postoperative recurrence in Fusobacterium nucleatum-positive (Fn-positive) CRC patients.

Patients And Methods: Clinical information and paraffin tissue specimens were collected from a retrospective cohort of 332 patients. The abundance of Fn in tumor tissue was measured using a quantitative polymerase chain reaction.

Fabrication of strain-sensing fibers with silver nanoparticles and reduced graphene oxide via wet spinning.

To advance the industrialization of flexible strain sensors, an innovative flexible sensing fiber was developed through a sophisticated wet spinning process. Silver trifluoroacetate and graphene oxide (GO) were combined with thermoplastic polyurethane (TPU) to prepare the fibers via wet spinning. Ascorbic acid was used toreduce the silver trifluoroacetate and graphene oxide within the polyurethane, causing the growth of silver nanoparticles to bond with reduced graphene oxide, forming a dual conductive pathway.

Choice versus no choice: Practical considerations for increasing choices.

Choice involves engaging in a selection response when multiple options are concurrently available. Choices can be incorporated into many components of behavior-analytic treatment such as providing clients with a choice between multiple items, activities, or tasks. We reviewed the main characteristics of 38 behavior-analytic articles that compared choice and no-choice conditions.

Self-Nanoemulsifying Drug Delivery System of Morin: A New Approach for Combating Acute Alcohol Intoxication.

Purpose: Acute alcohol intoxication (AAI) is a life-threatening medical condition resulting from excessive alcohol consumption. Our research revealed the potential of morin (MOR) in treating AAI. However, MOR's effectiveness against AAI was hindered by its poor solubility in water and low bioavailability.

Nanosized Zirconium-Organic Frameworks with Redox Behaviors for the Switchable Detection of Hypochlorous Acid and Ascorbic Acid.

Luminescent metal-organic frameworks (LMOFs) exhibit promising applications as chemical sensors, especially for organic-linker-based LMOFs due to their unlimited structures and pre- and postfunctionality. However, it is still a challenge to introduce specific functional groups into LMOFs as reaction sites for sensing. Herein, a new luminescent zirconium-based metal-organic framework (Zr-MOF), HIAM-4009L, is reported with underlying net.

Emission Library and Applications of 2,1,3-Benzothiadiazole and Its Derivative-Based Luminescent Metal-Organic Frameworks.

Organic linker-based luminescent metal-organic frameworks (LMOFs) have received extensive attention due to their promising applications in chemical sensing, energy transfer, solid-state-lighting and heterogeneous catalysis. Benefiting from the virtually unlimited emissive organic linkers and the intrinsic advantages of MOFs, significant progress has been made in constructing LMOFs with specific emission behaviors and outstanding performances. Among these reported organic linkers, 2,1,3-benzothiadiazole and its derivatives, as unique building units with tunable electron-withdrawing abilities, can be used to synthesize numerous emissive linkers with a donor-bridge-acceptor-bridge-donor type structure.

Full-Color Emissive Zirconium-Organic Frameworks Constructed via in Situ "One-Pot" Single-Site Modification for Tryptophan Detection and Energy Transfer.

Organic linker-based luminescent metal-organic frameworks (LMOFs) have received extensive studies due to the unlimited species of emissive organic linkers and tunable structure of MOFs. However, the multiple-step organic synthesis is always a great challenge for the development of LMOFs. As an alternative strategy, in situ "one-pot" strategy, in which the generation of emissive organic linkers and sequential construction of LMOFs happen in one reaction condition, can avoid time-consuming pre-synthesis of organic linkers.

Impact of Imine Bond Orientations and Acceptor Groups on Photocatalytic Hydrogen Generation of Donor-Acceptor Covalent Organic Frameworks.

Covalent organic frameworks (COFs) have emerged as one of the most studied photocatalysts owing to their adjustable structure and bandgaps. However, there is limited research on regulating the light-harvesting capabilities of acceptor building blocks in donor-acceptor (D-A) isomer COFs with different bond orientations. This investigation is crucial for elucidating the structure-property-performance relationship of COF photocatalysts.

Efficacy and safety of tranexamic acid on blood loss and seizures in patients undergoing meningioma resection: A systematic review and meta-analysis.

Introduction: It is unclear how tranexamic acid (TXA) affects blood loss and seizures in meningioma resections. We performed a systematic review and meta-analysis and tried to evaluate the effectiveness and safety of TXA use for patients undergoing meningioma resections.

Methods: Regards to this systematic review and meta-analysis (registered with CRD42023416693), we searched PubMed, Embase (Ovid), EBSCO, and Cochrane central library up to and including Oct 2023.

Characterization of radon gas transmission rate in pore structures of different rock layers by radon daughters inversion calculation.

Determining the transmission rate of radon gas in overburden strata is crucial for conducting a comprehensive study of radon gas's longitudinal and long-distance migration mechanisms. This study investigates the mineral components of rocks in the underground strata of the mining area using the X-ray diffraction method. Additionally, it examines the pore structure parameters of the rocks at different depths using the low-temperature nitrogen adsorption method.

Reticular Chemistry and In Situ "One-Pot" Strategy: A Dream Combination to Construct Metal-Organic Frameworks.

The establishment of reticular chemistry has significantly facilitated the development of porous materials, especially for metal-organic frameworks (MOFs). On the other hand, as an alternative approach, in situ "one-pot" strategy has been explored as a promising approach to constructing MOFs, in which the synthesis of organic linkers and the sequential construction of MOFs are integrated into one solvothermal condition. This strategy can efficiently avoid the limitations faced in the traditional construction method, such as time-consuming organic synthesis and multiple separation and purification.

Metalenses phase characterization by multi-distance phase retrieval.

Metalens, characterized by their unique functions and distinctive physical properties, have gained significant attention for their potential applications. To further optimize the performance of metalens, it is necessary to characterize the phase modulation of the metalens. In this study, we present a multi-distance phase retrieval system based on optical field scanning and discuss its convergence and robustness.

Reticular chemistry guided single-linker constructed pillar-layered metal-organic frameworks an "one-pot" strategy.

In the present work, we report a "two-in-one" strategy to construct single-linker-based pillar-layered metal-organic frameworks (PL-MOFs) guided by reticular chemistry an "one-pot" approach. Two carboxyl groups and one pyridine group are integrated into one molecular skeleton to form bifunctional organic linkers the reaction of pyridine-containing aldehyde and bicarboxylate-containing -phenylenediamine. During the synthesis of organic linkers, two zinc-based PL-MOFs, non-interpenetrated HIAM-3016-op and two-fold interpenetrated HIAM-3017-op, can be simultaneously constructed.

XRCC2 knockdown effectively sensitizes esophageal cancer to albumin-paclitaxel in vitro and in vivo.

Esophageal cancer (EC), a prevalent malignancy, has a high incidence and mortality. X-ray repair cross complementing 2 (XRCC2) functions on DNA damage and repair that works the progression of various cancers. Nevertheless, the role and mechanism of XRCC2 remain unknown in EC.

Intraoperative goal-directed fluid management and postoperative brain edema in patients having high-grade gliomas resections: a randomized trial.

Introduction: Patients with high-grade gliomas often have severe brain edema. Goal-directed fluid management protects neurological function, but whether reduces postoperative brain edema remains unknown.

Methods: Patients having elective resection of supratentorial malignant gliomas were randomly assigned to goal-directed versus routine fluid management.

Role of water in the formation of low-temperature coal oxidation products: An experimental isotope tracer study.

The interaction between water and coal is of great significance to the study of coal spontaneous combustion (CSC) in humid mine environments. Here, using an isotope tracing method to trace oxygen atoms in water, the role of water in the formation of CO, CO, product water, and other substances during CSC was quantitatively studied through thermogravimetry coupled with mass spectrometry (TG-MS). In addition, Pearson correlation analysis was used to evaluate the relationships between the amounts of CO and CO generated during CSC and the different functional groups.

Catalytic Asymmetric Access to Structurally Diverse -Alkoxy Amines via a Kinetic Resolution Strategy.

Chiral -alkoxy amines are increasingly vital substrates in bioscience. However, asymmetric synthetic strategies for these compounds remain scarce. Catalytic kinetic resolution represents an attractive approach to prepare structurally diverse enantiopure -alkoxy amines, which has remained elusive due to the notably reduced nucleophilicity of the nitrogen atom together with the low bond dissociation energies of labile NO-C and N-O bonds.

Reticular Chemistry Directed "One-Pot" Strategy to in situ Construct Organic Linkers and Zirconium-Organic Frameworks.

Zirconium-based metal-organic frameworks (Zr-MOFs) have emerged as one of the most studied MOFs due to the unlimited numbers of organic linkers and the varying Zr-oxo clusters. However, the synthesis of carboxylic acids, especially multitopic carboxylic acids, is always a great challenge for the discovery of new Zr-MOFs. As an alternative approach, the in situ "one-pot" strategy can address this limitation, where the generation of organic linkers from the corresponding precursors and the sequential construction of MOFs are integrated into one solvothermal condition.

A bacterial cellulose/polyvinyl alcohol/nitro graphene oxide double layer network hydrogel efficiency antibacterial and promotes wound healing.

In this study, graphene oxide (GO) was chemically modified utilizing concentrated nitric acid to produce a nitrated graphene oxide derivative (NGO) with enhanced oxidation level, improved dispersibility, and increased antibacterial activity. A double-layer composite hydrogel material (BC/PVA/NGO) with a core-shell structure was fabricated by utilizing bacterial cellulose (BC) and polyvinyl alcohol (PVA) binary composite hydrogel scaffold as the inner network template, and hydrophilic polymer (PVA) loaded with antibacterial material (NGO) as the outer network. The fabrication process involved physical crosslinking based on repeated freezing and thawing.

In Vivo Intelligent Fluorescence Endo-Microscopy by Varifocal Meta-Device and Deep Learning.

Endo-microscopy is crucial for real-time 3D visualization of internal tissues and subcellular structures. Conventional methods rely on axial movement of optical components for precise focus adjustment, limiting miniaturization and complicating procedures. Meta-device, composed of artificial nanostructures, is an emerging optical flat device that can freely manipulate the phase and amplitude of light.

Facile Tailoring of Metal-Organic Frameworks for Förster Resonance Energy Transfer-Driven Enhancement in Perovskite Photovoltaics.

Förster resonance energy transfer (FRET) has demonstrated its potential to enhance the light energy utilization ratio of perovskite solar cells by interacting with metal-organic frameworks (MOFs) and perovskite layers. However, comprehensive investigations into how MOF design and synthesis impact FRET in perovskite systems are scarce. In this work, nanoscale HIAM-type Zr-MOF (HIAM-4023, HIAM-4024, and HIAM-4025) is meticulously tailored to evaluate FRET's existence and its influence on the perovskite photoactive layer.

Reticular chemistry guided precise construction of zirconium-pentacarboxylate frameworks with 5-connected Zr clusters.

Zirconium-based metal-organic frameworks (Zr-MOFs) have been extensively studied due to their very rich structural chemistry. The combination of nearly unlimited carboxylic acid-based linkers and Zr clusters with multiple connectivities has led to diverse structures and specific properties of resultant Zr-MOFs. Herein, we demonstrate the successful use of reticular chemistry to construct two novel Zr-MOFs, HIAM-4040 and HIAM-4040-OH, with zfu topology.

Enzymatic-related network of catalysis, polyamine, and tumors for acetylpolyamine oxidase: from calculation to experiment.

The regulation of enzymes and development of polyamine analogs capable of controlling the dynamics of endogenous polyamines to achieve anti-tumor effects is one of the biggest challenges in polyamine research. However, the root of the problem remains unsolved. This study represents a significant milestone as it unveils, for the first time, the comprehensive catalytic map of acetylpolyamine oxidase that includes chemical transformation and product release kinetics, by utilizing multiscale simulations with over six million dynamical snapshots.