Predictive value of spectral dual-detector computed tomography for expression in stage I lung adenocarcinoma: development and validation of a novel nomogram.

Background: Programmed death ligand-1 () expression serves a predictive biomarker for the efficacy of immune checkpoint inhibitors (ICIs) in the treatment of patients with early-stage lung adenocarcinoma (LA). However, only a limited number of studies have explored the relationship between expression and spectral dual-layer detector-based computed tomography (SDCT) quantification, qualitative parameters, and clinical biomarkers. Therefore, this study was conducted to clarify this relationship in stage I LA and to develop a nomogram to assist in preoperative individualized identification of -positive expression.

Dynamic Reconfiguration and Local Polarization of NiFe-Layered Double Hydroxide-BiMoO Heterojunction for Enhancing Piezo-Photocatalytic Nitrogen Oxidation to Nitric Acid.

Constructing heterojunctions with vacancies has garnered substantial attention in the field of piezo-photocatalysis. However, the presence of interfacial vacancies can serve as charge-trapping sites, leading to the localization of electrons and hindering interfacial charge transfer. Herein, dual oxygen vacancies in the NiFe-layered double hydroxide and BiMoO induced interfacial bonds have been designed for the piezo-photocatalytic N oxidation to NO .

Immature central tumor tertiary lymphoid structures are associated with better prognosis in non-small cell lung cancer.

Background & Aims: Tertiary lymphoid structures (TLSs) are predictive biomarkers of favorable clinical outcomes and immunotherapy response in several solid malignancies, including non-small cell lung cancer (NSCLC). However, the relationship between TLSs and NSCLC prognosis has not been eludicated from the aspects of location, density, and maturity. This study aimed to investigate the clinicopathological and prognostic significance of TLSs in NSCLC.

Dual-Band All-Optical Logic Gates by Coherent Absorption in an Amorphous Silicon Graphene Metasurface.

The dual-band polarization-independent all-optical logic gate by coherent absorption effect in an amorphous silicon (a-Si) graphene metasurface is investigated theoretically and numerically. Taking the substrate effect into consideration, the coherent perfect absorption condition of the a-Si graphene metasurface is derived on the basis of the Cartesian multipole method. The coherent nearly perfect absorption of the a-Si graphene metasurface is realized by the interference of multipole moments and the interband transition of monolayer graphene, achieving peak values of 91% and 92% at 894.

Electronic configuration inversion in CdInS for efficient photocatalytic hydrogen peroxide generation coupled with selective benzylamine oxidation.

Vacancies engineering has sparked a huge interest in enhancing photocatalytic activity, but monovacancy simultaneously conducts as either electron or hole acceptor and redox reaction, worsening charge transfer and catalytic performance. Here, the concept of electronic inversion has been proposed through the simultaneous introduction of surface oxygen and S vacancies in CdInS (OS-CIS). Consequently, under mild conditions, the well-designed OS-CIS-200 demonstrated a strong rate of N-benzylidenebenzylamine production (2972.

Isolation, functional evaluation, and fermentation process optimization of probiotic Bacillus coagulans.

Bacillus coagulans is a probiotic agent widely used in various industries. In this study, we isolated a novel strain of B. coagulans, X26, from soil and characterized its properties.

Primary Undifferentiated Gallbladder Carcinoma With SMARCA4 Deletion: A Case Report and Review of the Literature.

Undifferentiated gallbladder carcinoma is a rare type of cancer with poor prognosis, due to the absence of specific clinical manifestations, and the final diagnosis depends on pathological and immunohistochemical examinations. However, only a few reports of SMARCA4-deficient undifferentiated gallbladder tumor have been published to date. Therefore, we report the diagnosis and treatment of an undifferentiated gallbladder carcinoma with SMARCA4 deficiency.

An R package for Survival-based Gene Set Enrichment Analysis.

Functional enrichment analysis is usually used to assess the effects of experimental differences. However, researchers sometimes want to understand the relationship between transcriptomic variation and health outcomes like survival. Therefore, we suggest the use of Survival-based Gene Set Enrichment Analysis (SGSEA) to help determine biological functions associated with a disease's survival.

Identification of tumor mutations in plasma based on mutation variant frequency change (MVFC).

To overcome the dependency of strategies utilizing cell-free DNA (cfDNA) on tissue sampling, the emergence of sequencing panels for non-invasive mutation screening was promoted. However, cfDNA sequencing with panels still suffers from either inaccuracy or omission, and novel approaches for accurately screening tumor mutations solely based on plasma without gene panel restriction are urgently needed. We performed unique molecular identifier (UMI) target sequencing on plasma samples and peripheral blood mononuclear cells (PBMCs) from 85 hepatocellular carcinoma (HCC) patients receiving surgical resection, which were divided into an exploration dataset (20 patients) or an evaluation dataset (65 patients).

Isolation and Genome-Based Characterization of Biocontrol Potential of YB-1631 against Wheat Crown Rot Caused by .

Fusarium crown rot (FCR) caused by is one of the most serious soil-borne diseases of wheat. Among 58 bacterial isolates from the rhizosphere soil of winter wheat seedlings, strain YB-1631 was found to have the highest in vitro antagonism to growth. LB cell-free culture filtrates inhibited mycelial growth and conidia germination of by 84.

Evaluation and Genome Analysis of YB-04 as a Potential Biocontrol Agent Against Wilt and Growth Promotion Agent of Cucumber.

Cucumber wilt caused by f.sp. () is a highly destructive disease that leads to reduced yield in cucumbers.

Genomic and Phenotypic Insights into the Potential of YB-15 Isolated from Rhizosphere to Biocontrol against Crown Rot and Promote Growth of Wheat.

crown rot caused by is one of the most devastating diseases of wheat worldwide causing major yield and economic losses. In this study, strain YB-15 was isolated from soil of wheat rhizosphere and classified as by average nucleotide identity analysis. It significantly reduced crown rot with a control efficacy of 81.

A Plasmonic Infrared Multiple-Channel Filter Based on Gold Composite Nanocavities Metasurface.

A plasmonic near-infrared multiple-channel filter is numerically and experimentally investigated based on a gold periodic composite nanocavities metasurface. By the interference among different excited plasmonic modes on the metasurface, the multipeak extraordinary optical transmission (EOT) phenomenon is induced and utilized to realize multiple-channel filtering. Investigated from the simulated transmission spectrum of the metasurface, the positions and intensity of transmission peaks are tuned by the geometrical parameters of the metasurface and environmental refractive index.

Biological Control of Take-All and Growth Promotion in Wheat by YB-10.

Wheat is a worldwide staple food crop, and take-all caused by var. can lead to a tremendous decrease in wheat yield and quality. In this study, strain YB-10 was isolated from wheat rhizospheric soil and identified as by morphology and 16S rRNA gene sequencing.

Bidirectional Electromagnetically Induced Transparency Based on Coupling of Magnetic Dipole Modes in Amorphous Silicon Metasurface.

A bidirectional electromagnetically induced transparency (EIT) arising from coupling of magnetic dipole modes is demonstrated numerically and experimentally based on nanoscale a-Si cuboid-bar metasurface. Analyzed by the finite-difference time-domain (FDTD) Solutions, both the bright and dark magnetic dipole mode is excited in the cuboid, while only the dark magnetic dipole mode is excited in the bar. By breaking the symmetry of the cuboid-bar structure, the destructive interference between bright and dark magnetic dipole modes is induced, resulting in the bidirectional EIT phenomenon.

Broadened Angle-Insensitive Near-Perfect Absorber Based on Mie Resonances in Amorphous Silicon Metasurface.

A broadband near-perfect absorber is analyzed by an amorphous silicon (a-Si) hook shaped nanostructure metasurface. The transmission and reflection coefficients of the metasurface are investigated in the point electric and magnetic dipole approximation. By combining square and semicircle nanostructures, the effective polarizabilities of the a-Si metasurface calculated based on discrete dipole approximation (DDA) exhibit broadened peaks of electric dipole (ED) and magnetic dipole (MD) Mie resonances.

Broadened band near-perfect absorber based on amorphous silicon metasurface.

A dielectric broadened band near-perfect absorber based on an amorphous silicon(a-Si) T-shaped nanostructure metasurface is investigated numerically and experimentally. The simultaneous suppressed transmission and reflection of the a-Si nanostructure metasurface are achieved by investigating the interference of the periodically adjustable electric dipole(ED) and magnetic dipole(MD) Mie resonances. The absorption of the a-Si nanostructure metasurface approaches the maximum of 95% in simulation and 80% in experiment with a top-hat shape in the spectral range from 580 nm to 620 nm by employing the T-shaped nanostructure.

Plasmonic transmitted optical differentiator based on the subwavelength gold gratings.

A nanoscale plasmonic optical differentiator based on subwavelength gold gratings is investigated theoretically and experimentally without Fourier transform lenses and prisms. In the vicinity of surface plasmon resonance (SPR), the transfer function of subwavelength gold gratings is derived by optical scattering matrix theory. Simulated by the finite difference time domain (FDTD) method, the wavelengths of optical spatial differentiation performed by subwavelength gold gratings are tuned by the grating period and duty cycle, while the throughput of edge extraction is mainly adjusted by the grating thickness.

Foliar-sprayed manganese sulfate improves flavonoid content in grape berry skin of Cabernet Sauvignon (Vitis vinifera L.) growing on alkaline soil and wine chromatic characteristics.

Flavonoids are key determinants of grape quality and wine color. Grapevines growing in alkaline soil are prone to manganese deficiency, which can decrease the contents of secondary metabolites, including flavonoids. We determined the effects of a foliar Mn treatment (MnSO·HO) of Cabernet Sauvignon grapevines (V.

Tunable polarization-independent dual-band coherent perfect absorber based on metal-graphene nanoring structure.

A dual-band polarization-independent coherent perfect absorber(CPA) based on metal-graphene nanostructure is proposed, which is composed of golden nanorings with different sizes on graphene monolayer. Based on the finite-difference time-domain (FDTD) solutions, coherent perfect absorptions of the metal-graphene CPA are achieved at frequencies of 50.54 THz and 43.

Tunable polarization-independent plasmonically induced transparency based on metal-graphene metasurface.

A tunable polarization-independent dual-band plasmonically induced transparency (PIT) device based on metal-graphene nanostructures is proposed theoretically and numerically at mid-infrared frequencies, which is composed of two kinds of center-symmetric metallic nanostructure array with different sizes and element numbers placed on separate graphene interdigitated finger sets, respectively. The coupled Lorentz oscillator model is used to explain the physical mechanism of PIT effect at multiple frequency domains. The finite-difference time-domain (FDTD) solutions are employed to simulate the characteristics of the polarization-independent metal-graphene PIT device, which is consistent with the theoretical analysis.

Independently tunable dual-band plasmonically induced transparency based on hybrid metal-graphene metamaterials at mid-infrared frequencies.

A tunable dual-band plasmonically induced transparency (PIT) device based on hybrid metal-graphene nanostructures is proposed theoretically and numerically at mid-infrared frequencies, which is composed of two kinds of gold dolmen-like structures with different sizes placed on separate graphene interdigitated finger sets respectively. The coupled Lorentz oscillator model is used to explain the physical mechanism of the PIT effect at multiple frequency domains. The finite-difference time-domain (FDTD) solutions are employed to simulate the characteristics of the hybrid metal-graphene dual-band PIT device.

Plasmonic wavelength splitter based on a metal-insulator-metal waveguide with a graded grating coupler.

A plasmonic wavelength splitter based on a sub-wavelength metal-insulator-metal (MIM) periodic rectangle wrinkle waveguide with a graded grating coupler is theoretically analyzed and experimentally demonstrated. The surface plasmon polaritons (SPPs), excited in the metal grating with wavelength selection, are deflected by the graded difference according to the aplanatic parametric principle. The wave vector of the deflected SPPs meets the phase-matching condition and couples into the periodic rectangle wrinkle waveguide with a plasmonic bandgap.

Tunable multispectral plasmon induced transparency based on graphene metamaterials.

A dynamically wavelength tunable multispectral plasmon induced transparency (PIT) device based on graphene metamaterials, which is composed of periodically patterned graphene double layers separated by a dielectric layer, is proposed theoretically and numerically in the terahertz frequency range. Considering the near-field coupling of different graphene layers and the bright-dark mode coupling in the same graphene layer, the coupled Lorentz oscillator model is adapted to explain the physical mechanism of multispectral EIT-like responses. The simulated transmission based on the finite-difference time-domain (FDTD) solutions indicates that the shifting and depth of the EIT resonances in multiple PIT windows are controlled by different geometrical parameters and Fermi energies distributions.