Comprehensive Application of Autologous Costal Cartilage Grafts in Rhino- and Mentoplasty.

Background: Underdevelopment of nose and chin in East Asians is quite common. Rhinoplasty and mentoplasty are effective procedures to solve the above-depicted defects and can achieve remarkable cosmetic effects. An autologous costal cartilage graft has become an ideal material for rhinoplasty, especially for revision surgery.

Ultrathin atomic Mn-decorated formamide-converted N-doped carbon for efficient oxygen reduction reaction.

It is of great importance to control the thickness of catalytic components to enable maximum catalyst utilization and strong catalyst-substrate interaction since electrocatalytic reactions occurring at the interface of catalysts involve a one or two-atom thick active layer. Herein, we achieved an ultrathin deposition of a 2.5 ± 0.

Chlorogenic acid attenuates cadmium-induced intestinal injury in Sprague-Dawley rats.

Chronic exposure to cadmium (Cd) causes remarkable damage to the liver and gastrointestinal tract. Previous studies have revealed that chlorogenic acid (CGA) could improve the intestinal barrier integrity for weaned rats. Hence, this study sought to investigate the protective effects of CGA from pure reagent and sunflower seed extract (SSE) on growth performance, antioxidant indicators, inflammatory biomarkers and intestinal barrier function in Cd treated rats.

Erratum: Self-Healing and Injectable Hydrogel for Matching Skin Flap Regeneration.

[This corrects the article DOI: 10.1002/advs.201801555.

Clinical pathway for the community-level management of patients with type 2 diabetes.

Aim: To assess the results of a type 2 diabetes electronic clinical pathway using an empirical study.

Methods: A literature review and expert meetings were used to formulate a community-based clinical pathway document for type 2 diabetes, and an electronic clinical pathway platform was developed. An intervention study method was adopted in which the electronic clinical pathway management intervention was applied in type 2 diabetes patients from the Weifang Community Health Service Center.

Exploration and practice of the "1 + 10 + 1100000" model.

The exploration and practice of the "1 + 10 + 1100000" model of local medical consortium includes three aspects: graded diagnosis and treatment, two-way referral, and dynamic flow; seamless connection between general practice and specialty to realize health management; and establishment of the "community health center-East Hospital-Tongji University" teaching platform.

Evaluation of the implementation and effect of the healthcare cloud information platform for diabetes self-management: A case study in Shanghai.

With the high prevalence of diabetes, its long-term treatment, and many complications, there is a need for a new diabetes self-management model in developing countries. Therefore, this study aimed to assess the implementation and effect of a new diabetes self-management model, known as the healthcare cloud information platform, in Shanghai, China. The implementation of the new model was evaluated in terms of the equipment coverage in community health service centres and the services provided.

Evaluation of a community-based hypertension self-management model with general practitioners.

Background: Preventive interventions of hypertension and health care activities are often performed in the community and at home. Studies have shown that self-management plays an indispensable role in the management of chronic diseases. This study aimed to explore an innovative community-based hypertension self-management model and to evaluate its effects.

Effect of chronic disease self-management program on the quality of life of HIV-infected men who have sex with men: An empirical study in Shanghai, China.

Objectives: The HIV/AIDS epidemic rages on in China, particularly among men who have sex with men (MSM). MSM with HIV/AIDS also tend to have poorer quality of life than other members of the population. A major contributor to these issues is the huge gap between the increasing demand of MSM for medical services and the availability of such services; their current needs cannot be met only with the services of the Chinese Center for Disease Control and Prevention.

An evaluation of the effects of general practitioner-supported patient noncommunicable diseases control model in Shanghai, China.

Noncommunicable diseases (NCDs) are the leading cause of death worldwide. A litmus test for China's health reform is its ability to effectively deal with NCDs. The general practitioners (GPs)-supported NCD control model was designed to address ways to effectively prevent and control NCDs population-wide.

Colossal Elastocaloric Effect in Ferroelastic Ni-Mn-Ti Alloys.

Energy-efficient and environment-friendly elastocaloric refrigeration, which is a promising replacement of the conventional vapor-compression refrigeration, requires extraordinary elastocaloric properties. Hitherto the largest elastocaloric effect is obtained in small-size films and wires of the prototype NiTi system. Here, we report a colossal elastocaloric effect, well exceeding that of NiTi alloys, in a class of bulk polycrystalline NiMn-based materials designed with the criterion of simultaneously having large volume change across phase transition and good mechanical properties.

Light-Driven Active Proton Transport through Photoacid- and Photobase-Doped Janus Graphene Oxide Membranes.

Biological electrogenic systems use protein-based ionic pumps to move salt ions uphill across a cell membrane to accumulate an ion concentration gradient from the equilibrium physiological environment. Toward high-performance and robust artificial electric organs, attaining an antigradient ion transport mode by fully abiotic materials remains a great challenge. Herein, a light-driven proton pump transport phenomenon through a Janus graphene oxide membrane (JGOM) is reported.

L-Arginine and N-carbamoylglutamic acid supplementation enhance young rabbit growth and immunity by regulating intestinal microbial community.

Objective: An experiment was conducted to determine the effects of L-arginine (L-Arg) and N-carbamoylglutamic acid (NCG) on the growth, metabolism, immunity and community of cecal bacterial flora of weanling and young rabbits.

Methods: Eighteen normal-grade male weanling Japanese White Rabbits (JWR) were selected and randomly divided into 6 groups with or without L-Arg and NCG supplementation. The whole feeding process was divided into weanling stage (Day 37 to 65) and young stage (Day 66 to 85).

Chemical Composition, Antioxidant, and Antimicrobial Activities of (L.) Nash Essential Oil Extracted by Carbon Dioxide Expanded Ethanol.

In the present study, the composition of essential oil isolated from the roots of (L.) Nash, harvested in China, was studied, along with the bioactivities. A green novel method using an eco-friendly solvent, CO-pressurized ethanol, or carbon dioxide expanded ethanol (CXE) was employed to isolate the essential oil from the root of (L.

The ethylene response factor VaERF092 from Amur grape regulates the transcription factor VaWRKY33, improving cold tolerance.

Cold stress is a major limiting factor in grape (Vitis) productivity. In this study, we characterized a cold-responsive ethylene response factor (ERF) transcription factor, VaERF092, from Amur grape (Vitis amurensis). VaERF092 expression was induced by both low temperatures and the ethylene precursor 1-aminocyclopropane-1-carboxylate (ACC), but was suppressed by treatment with the ethylene inhibitor aminoethoxyvinylglycine (AVG) under cold conditions.

Overexpression of VaWRKY12, a transcription factor from Vitis amurensis with increased nuclear localization under low temperature, enhances cold tolerance of plants.

Overexpression of VaWRKY12, whose nuclear translocation increased under low temperature, enhanced the cold tolerance of Arabidopsis and grapevine calli and significantly increased the expression of antioxidant-related genes. Low temperature causes injuries to buds during winter and to young shoots during early spring, thereby affecting grapevine quality and yield. Understanding the regulatory mechanisms of cold stress responses is essential for the breeding of new grapevine cultivars with excellent cold tolerance.

[Investigation on protective effect and efficacy difference of extract of Schisandrae Sphenantherae Fructus and Schisandrae Chinensis Fructus against acetaminophen-induced liver injury].

The study was aimed to investigate the protective effect and pharmacodynamic difference of the ethanol extracts of Schisandrae Sphenantherae Fructus and Schisandrae Chinensis Fructus on the drug-induced liver injury induced by acetaminophen.The cell activations of LO2 cells treated by Schisandrae Sphenantherae Fructus and Schisandrae Chinensis Fructus ethanol extracts were tested by CCK-8 essay.The effects of ethanol extracts on cell survival rate,the activities of ALT and AST in culture medium were detected based on the injury model of LO2 cells induced by APAP.

Boosting oxygen evolution of single-atomic ruthenium through electronic coupling with cobalt-iron layered double hydroxides.

Single atom catalyst, which contains isolated metal atoms singly dispersed on supports, has great potential for achieving high activity and selectivity in hetero-catalysis and electrocatalysis. However, the activity and stability of single atoms and their interaction with support still remains a mystery. Here we show a stable single atomic ruthenium catalyst anchoring on the surface of cobalt iron layered double hydroxides, which possesses a strong electronic coupling between ruthenium and layered double hydroxides.

Priming of HIV-1-specific CD8 T cells with strong functional properties from naïve T cells.

Background: HIV-1-specific CD8 T cells are required for immune suppression of HIV-1 replication and elimination of the associated viral reservoirs. However, effective induction of functional HIV-1-specific CD8 T cells from naïve cells remains problematic in the setting of human vaccine trials. In this study, we investigated priming of functional HIV-1-specific CD8 T cells from naïve cells.

Highly efficient and stable solar-powered desalination by tungsten carbide nanoarray film with sandwich wettability.

Solar-powered desalination is a promising way to resolve the worldwide water crisis for its low consumption and simple facility. Considering the fragility and aggregations of traditional materials, which may decrease efficiency, we herein introduce a robust tungsten carbide (WC) nanoarray film as a stable and efficient photothermal material, whose absorption is over 97.5% throughout almost the whole solar spectrum range (220-2200 nm) due to nanoarray structure and thus enhanced localized surface plasmon resonance.

Enhancing photocatalytic activity on gas-phase heavy metal oxidation with self-assembled BiOI/BiOCl microflowers.

A one-pot synthetic approach to prepare self-assembled BiOI/BiOCl microflowers by a template-free coprecipitation method at room temperature has been developed. The physicochemical structure of BiOI/BiOCl microflowers were characterized using transmission electron microscopy (TEM), high resolution TEM (HRTEM), scanning electron microscopy (SEM). The composition information and bonding energy structure of the BiOI/BiOCl microflowers were studied by X-ray diffraction (XRD) and high-resolution X-ray photoelectron spectra (XPS), Fourier Transform Infrared Spectroscopy (FTIR), UV-vis diffuse reflectance spectroscopy (DRS) analysis and photoluminescence (PL) spectra.

Surface Restraint Synthesis of an Organic-Inorganic Hybrid Layer for Dendrite-Free Lithium Metal Anode.

Li metal is considered to be the most attractive anode for next-generation batteries because of its high specific capacity and low reduction potential. However, uncontrolled Li dendrite growth and low Coulombic efficiency cause severe capacity decay and safety issues. Here we propose a LiCl contained inorganic-organic hybrid layer on Li metal surface by a surface restraint dehalogenation reaction, which is highly uniform and features lithiophilic property as well as high ionic conductivity that can inhibit Li dendrite growth effectively.

Self-Healing and Injectable Hydrogel for Matching Skin Flap Regeneration.

The fabrication of highly biocompatible hydrogels with multiple unique healing abilities for the whole healing process, for example, multifunctional hydrogels with injectable, degradation, antibacterial, antihypoxic, and wound healing-promoting properties that match the dynamic healing process of skin flap regeneration, is currently a research challenge. Here, a multifunctional and dynamic coordinative polyethylene glycol (PEG) hydrogel with mangiferin liposomes (MF-Lip@PEG) is developed for clinical applications through Ag-S coordination of four-arm-PEG-SH and Ag. Compared to MF-PEG, MF-Lip@PEG exhibits self-healing properties, lower swelling percentages, and a longer endurance period.