Publications by authors named "XiaoHui Chang"

Background: In recent years, percutaneous kyphoplasty (PKP) has been increasingly used in clinical settings.

Objective: In this study, we aimed to determine the analgesic effect of intravertebral lidocaine injections in PKP.

Methods: A total of 60 patients who were treated with PKP were enrolled in this study.

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Listeria monocytogenes is a food-borne pathogen that can cause human listeriosis. The main cause of L.monocytogenes poisoning is the consumption of contaminated or processed foods, of which meat is the main one.

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Misinformation on social media has become a horrendous problem in our society. Fact-checks on information often fall behind the diffusion of misinformation, which can lead to negative impacts on society. This research studies how different factors may affect the spread of fact-checks over the internet.

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Imatinib, the first generation of tyrosine kinase inhibitor, is used to treat and improve the prognosis of chronic myelogenous leukemia (CML). Clinical data suggest that imatinib could cross the blood-testis barrier and reduces the fertility of patients with CML-chronic phase. However, its exact molecular mechanism has not been fully elucidated.

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Article Synopsis
  • - A ZnO/diamond structure UV photodetector was created by depositing ZnO films of 50 and 100 nm thickness on diamond substrates using a sputtering technique.
  • - The photodetector's photocurrent gain in the UV range was significantly influenced by the thickness of the ZnO films, achieving gains of 14.3 A/W and 308 A/W for the 50 nm and 100 nm films, respectively.
  • - Peak responsivities for both film thicknesses occurred at 270 nm, with additional shoulder peaks noted at 240 nm and 290 nm, likely corresponding to properties of the diamond and ZnO materials.
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Near-infrared fluorescence probes (NIFPs) have been widely used in immunoassay, bio-imaging and medical diagnosis. We review the basic principles of near-infrared fluorescence and near-infrared detection technology, and summarize structures, properties and characteristics of NIFPs (i.e.

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Fabrication of hydrogen-terminated diamond (H-diamond) field-effect transistor (FET) with AlO dielectric layer has been successfully carried out. The AlO layer was formed by auto-oxidizing 6 nm Al film in the air at room temperature, and a FET without AlO dielectric layer has also been fabricated for comparison. For both FETs, 100 nm Al layers were deposited as the gate electrodes, respectively.

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In this study, a Ti-diamond-Ti structured ultraviolet photodetector was fabricated on a homoepitaxial diamond layer with an oxygen-terminated surface. The properties of the Ti/diamond schottky contact were measured using X-ray photoelectron spectroscopy, and the barrier height was found to be 1.15 eV.

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Investigation of ohmic contact between iridium (Ir) film and hydrogen-terminated single crystal diamond has been carried out with annealing temperature from 300 to 600 °C in argon (Ar) and hydrogen ambient. Electrodes were deposited on hydrogen-terminated single crystal diamond by electron beam evaporation technique, and specific contact resistivity has been measured by transmission line model. The interface between Ir film and hydrogen-terminated single crystal diamond was characterized by transmission electron microscopy and energy dispersive X-ray spectroscopy.

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Background: Imatinib is a first-line tyrosine kinase inhibitor for treating chronic myelogenous leukaemia (CML) and has greatly improved the prognosis of this disease. An increasing number of CML patients of reproductive age are diagnosed each year, and the impact of imatinib on fertility is a major concern. Providing useful advice to these patients regarding the choice of their therapeutic treatment is very important.

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We propose a novel statistical framework by supplementing case-control data with summary statistics on the population at risk for a subset of risk factors. Our approach is to first form two unbiased estimating equations, one based on the case-control data and the other on both the case data and the summary statistics, and then optimally combine them to derive another estimating equation to be used for the estimation. The proposed method is computationally simple and more efficient than standard approaches based on case-control data alone.

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Article Synopsis
  • - This study aims to analyze traditional Chinese medicine (CM) prescription laws for treating aplastic anemia (AA) by reviewing literature from various medical sources between 1979 and 2009.
  • - A total of 311 relevant articles were identified, detailing 677 prescriptions that utilized 254 different Chinese herbs, focusing on their medicinal uses, such as invigorating deficiency and clearing heat.
  • - The research established four core drug groups based on their usage frequency in prescriptions, highlighting six potential composing laws for effective treatment, emphasizing the importance of certain herbs in the management of AA.
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Objective: To study the regulatory effects of psoralen (PSO) plus ultraviolet A (UVA), which is PUVA, on cell apoptosis of human leukemia cell line NB4 and signal pathway of cell apoptosis.

Methods: Human leukemia cell line NB4 was cultured in vitro. The NB4 cells were treated with PSO extracted from Chinese medicine psoralea fruits at different concentrations (0, 5, 10, 20 and 40 microL) plus UVA of wave length 360 nm at different irradiation time points (0 and 5 min).

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Background: To investigate the effects of treatment with Multi component Chinese Medicine Jinzhida (JZD) on behavioral deficits in diabetes-associated cognitive decline (DACD) rats and verify our hypothesis that JZD treatment improves cognitive function by suppressing the endoplasmic reticulum stress (ERS) and improving insulin signaling transduction in the rats' hippocampus.

Methods: A rat model of type 2 diabetes mellitus (T2DM) was established using high fat diet and streptozotocin (30 mg/kg, ip). Insulin sensitivity was evaluated by the oral glucose tolerance test and the insulin tolerance test.

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Objective: To investigate the effect of post-remission therapy mainly with Compound Huangdai Tablet (CHDT) on long-term survival of patients with acute promyelocytic leukemia (APL).

Methods: One hundred and twelve APL patients were treated after remission mainly with CHDT administered alternately with chemotherapeutic projects such as HACP, HAOP, HAEP and HAMP. The relapse rate and relapse-free survival (RFS) rate in them were estimated by bone marrow examination.

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Objective: To study the diversity of lactic acid bacteria (LAB) and dominant LAB in fermented cabbage.

Methods: Culture-dependent and -independent (16S rRNA gene clone libraries were constructed) methods were used to determine the composition of LAB in fermented cabbage.

Results: Ninety LAB isolated from fermented cabbage were identified as species of Lactobacillus and Leuconostoc, whereas 115 clones of the 16S rRNA gene sequence from fermented cabbage DNA were identified as Lactobacillus, Weissella, Pediococcus and Leuconostoc.

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