Combined analysis of transcriptomics and metabolomics showed that SNAC4 and SNAC9 are negative regulators of the resistance to Botrytis cinerea in tomato.

NAC (NAM, ATAF1/2 and CUC2) is a transcription factor which contributes to the response for both biotic and abiotic stresses. In this study, the regulatory effects and potential mechanisms of SNAC4/9 on resistance to Botrytis cinerea (B. cinerea) were investigated by the differences in physiological and biochemical indices as well as transcriptional and metabolic profiles between SNAC4/9 overexpressed (OE-SNAC4/9) and wild-type (WT) tomato fruit inoculated with B.

Bioactive compounds regulate appetite through the melanocortin system: a review.

Obesity, a significant health crisis, arises from an imbalance between energy intake and expenditure. Enhancing appetite regulation has garnered substantial attention from researchers as a novel and effective strategy for weight management. The melanocortin system, situated in the hypothalamus, is recognized as a critical node in the regulation of appetite.

Carvacrol enhances antioxidant activity and slows down cell wall metabolism by maintaining the energy level of 'Guifei' mango.

Background: Postharvest mango fruit are highly susceptible to rapid ripening, softening and senescence, greatly limiting their distribution. In this study, we evaluated the potential effects of carvacrol (0.06 g L) on mango (25 ± 1 °C) and the mechanisms by which it regulates antioxidant activity, energy and cell wall metabolism.

Chitosan-ginger essential oil nanoemulsions loaded gelatin films: A biodegradable material for food preservation.

The alarming issue of food waste, coupled with the potential risks posed by petroleum-based plastic preservation materials to both the environment and human health necessitate innovative solutions. In this study, we prepared nanoemulsions (NEs) of chitosan (CS) and ginger essential oil (GEO) and systematically evaluated the effects of varying NEs concentrations (0, 10 %, 30 %, 50 %) on the physicochemical properties and biological activities of gelatin films. These films were subsequently applied to blueberry preservation.

Maintaining quality of postharvest green pepper fruit using melatonin by regulating membrane lipid metabolism and enhancing antioxidant capacity.

Green pepper quality often deteriorates during storage because of membrane lipid damage and oxidative stress. This study investigated the effects of exogenous melatonin (MT) on green pepper storage quality, membrane lipids, and antioxidant metabolism. The results showed that MT increased the activities of superoxide dismutase, catalase, ascorbate peroxidase, peroxidase, monodehydroascorbate reductase, and dehydroascorbate reductase in green peppers compared to the control group.

Scoparone from Thunb. induces apoptosis in HepG2 cells via activation of both intracellular and extracellular pathways.

Six separated compounds were identified from Thunb., and they were 7-methoxycoumarin (1), 6,7-dimethoxycoumarin (2), 7-hydroxy-6-methoxycoumarin (3), quercetin (4), chlorogenic acid (5) and caffeic acid (6). Among them, 6,7-dimethoxycoumarin, as known as scoparone, was the most effective on scavenging ABTS free radicals (IC = 0.

Rheological properties, gel properties and 3D printing performance of soy protein isolate gel inks added with different types of apricot polysaccharides.

A soybean protein isolate (SPI)-apricot polysaccharide gel with hypolipidemic activity that can be used for 3D printing was prepared and the mechanism of its gel formation was studied in this work. The results demonstrated that adding apricot polysaccharide to SPI could effectively improve the bound water content, viscoelastic properties and rheological properties of the gels. Low-field NMR, FT-IR spectroscopy and surface hydrophobicity confirmed that the interactions between SPI and apricot polysaccharide were mainly realized by electrostatic interactions, hydrophobic and hydrogen bonding.

CRISPR/Cas9-mediated SNAC9 mutants reveal the positive regulation of tomato ripening by SNAC9 and the mechanism of carotenoid metabolism regulation.

NAC transcriptional regulators are crucial for tomato ripening. Virus-induced gene silencing (VIGS) of (, Gene ID: 101248665) affects tomato ripening, and is involved in ethylene and abscisic acid (ABA) metabolic pathways. However, the function of in pigment metabolism in tomatoes remains unclear.

The characterization of antimicrobial nanocomposites based on chitosan, cinnamon essential oil, and TiO for fruits preservation.

The freshness and safety of fruits have always been crucial issues in the development of the industry. However, the existing fresh-keeping methods have limited effect, meanwhile, the preservation mechanism of different materials. In this study, Cinnamon essential oil (CEO), TiO and chitosan (CS) were compounded to prepare safe and renewable nanocomposites (CS-T-C) for fruit preservation.

Glycine betaine inhibits postharvest softening and quality decline of winter jujube fruit by regulating energy and antioxidant metabolism.

Winter jujube fruit easily softens after harvest. To investigate the effects of glycine betaine (N,N,N-trimethylglycine; GB) treatment on the quality of postharvest jujubes, fresh winter jujubes (Zizyphus jujuba Mill. cv.

Mechanisms of Biochanin A Alleviating PM2.5 Organic Extracts-Induced EMT of A549 Cells through the PI3K/Akt Pathway.

Epithelial-mesenchymal transition (EMT) is an important step in tumor progression, which enables tumor cells to acquire migration and invasion characteristics. The aim of this study was to investigate the mechanism of biological biochanin A (BCA) in ameliorating fine particulate matter (PM2.5) lung injury.

Synergistic Hypolipidemic Effects and Mechanisms of Phytochemicals: A Review.

Hyperlipidemia, a chronic disorder of abnormal lipid metabolism, can induce obesity, diabetes, and cardiovascular and cerebrovascular diseases such as coronary heart disease, atherosclerosis, and hypertension. Increasing evidence indicates that phytochemicals may serve as a promising strategy for the prevention and management of hyperlipidemia and its complications. At the same time, the concept of synergistic hypolipidemic and its application in the food industry is rapidly increasing as a practical approach to preserve and improve the health-promoting effects of functional ingredients.

Proteomic analysis reveals the mechanism of green regulation in garlic puree induced by purple light stress.

Greening is an undesirable appearance in garlic puree during processing. Our previous study indicated that purple light could induce the greening changes in garlic. In order to investigate the mechanism of green regulation in garlic puree, purple light-induced greening and nongreening garlic puree were used as materials to investigate the differentially expressed proteins (DEPs) by sodium dodecyl-sulfate polyacrylamide gel electrophoresis and data-independent acquisition (DIA) technology.

Enhanced extraction of bioactive natural products using ultrasound-assisted aqueous two-phase system: Application to flavonoids extraction from jujube peels.

The ultrasound-assisted aqueous two-phase extraction (UA-ATPE) was employed to develop an effective technique for the extraction of flavonoids from jujube peels (JPs). The extraction conditions were further optimized as KHPO 35% (w/w), ethanol 20% (w/w), solid-liquid ratio 1:30 g/mL (w/v), ultrasonic power 200 W, and extraction time 50 min. Moreover, rutin, quercetin 3-β-d-glucoside, and kaempferol-3-O-rutinosid were identified as the main flavonoids by UPLC-MS/MS.

Propyl Gallate Treatment Improves the Postharvest Quality of Winter Jujube ( Mill. cv. Dongzao) by Regulating Antioxidant Metabolism and Maintaining the Structure of Peel.

The quality and color of winter jujube fruits are easy to change after harvest. We studied the regulation mechanism of propyl gallate (PG) on post-harvest physiological quality of winter jujube, from the perspective of antioxidant metabolism and peel structure. In our research, winter jujube fruits were treated with 0.

Toxicology of respiratory system: Profiling chemicals in PM for molecular targets and adverse outcomes.

Numerous studies have shown that the increasing trend of respiratory diseases have been closely associated with the endogenous toxic chemicals (polycyclic aromatic hydrocarbons, heavy metal ions, etc.) in PM. In the present study, we aim to determine the strong correlations between the chemicals in PM and the adverse consequences.

Age-dependent alteration in metabolism of vitamin B , neurotransmitters, and amino acids after 4'-O-methylpyridoxine administration in rats.

4'-O-methylpyridoxine (MPN), a recognized antivitamin B compound, is a potentially poisonous substance found in Ginkgo biloba L. In this work, the effects of MPN on the metabolism of vitamin B , neurotransmitters, and amino acids were compared in the plasma and brain of young and adult rats under various administration times. Results showed that the contents of MPN residues in the plasma and brain of young rats were 12.

Nutritional constituent and health benefits of chickpea (Cicer arietinum L.): A review.

Chickpea (Cicer arietinum L.), an annual plant of the Fabaceae family, is mainly grown in temperate and semiarid regions. Its biological activity and beneficial contribution to human health have been scientifically confirmed as an essential source of nutritional components.

Different regulatory mechanisms of plant hormones in the ripening of climacteric and non-climacteric fruits: a review.

This review contains the regulatory mechanisms of plant hormones in the ripening process of climacteric and non-climacteric fruits, interactions between plant hormones and future research directions. The fruit ripening process involves physiological and biochemical changes such as pigment accumulation, softening, aroma and flavor formation. There is a great difference in the ripening process between climacteric fruits and non-climacteric fruits.