[Integrated Three-steps Method for Identifying Priority Pollutants in Reclaimed Water].

Trace organic contaminants （TrOCs） in reclaimed water can pose potential ecological and health risks during long-term reuse, but the current water quality standards have not restricted their limits. For preventing and controlling the potential risks from TrOCs, an integrated method EHL for identifying priority pollutants in reclaimed water was proposed. This method followed three steps： First, a meta-analysis was performed to assess the exposure of TrOCs in reclaimed water, and a database of TrOCs exposure （E） was established.

Evaluation of the microbial community in various saline alkaline-soils driven by soil factors of the Hetao Plain, Inner Mongolia.

Soil microbial communities play a crucial role in maintaining diverse ecosystem functions within the saline-alkali soil ecosystems. Therefore, in this study, we collected various saline-alkaline soils from across the Inner Mongolia Hetao irrigation area. The soil chemical properties were analyzed, and the microbial diversity of bacteria and fungi was measured using 16 S rRNA and ITS rRNA amplicon sequencing.

Complementary therapy with Chinese aromatic herbs to promote awakening in a comatose patient: A case report.

Rationale: Traumatic brain injury frequently leads to prolonged coma, posing significant medical management challenges. Complementary therapies, including traditional Chinese herbal medicine, have been investigated as potential interventions in comatose patients. Chinese aromatic herbs, such as Borneolum (Bingpian), Moschus (Shexiang), and Acori tatarinowii rhizoma (Shichangpu), have long been believed to be "resuscitation with aromatics" based on traditional Chinese medicines theory.

Further screening of SNP loci of eggshell translucency related genes and evaluation of genetic effects.

Eggshell translucency is a widespread issue in the field of egg quality. Previous research has established that the heritability of eggshell translucency is relatively low or moderate. Scientists have also successfully identified SNP loci related to eggshell translucency on different chromosomes by using gene chips and single-variant GWAS.

Influence of Ocular Biometric Parameters on Intraocular Lens Position: A Prospective Cohort Study.

Purpose: To assess the influence of ocular biometric parameters on intraocular lens (IOL) tilt and decentration after cataract surgery.

Methods: Patients scheduled for cataract surgery were screened for inclusion in this prospective cohort study. Tilt and decentration of the crystalline lens and IOL were measured using the CASIA2 (Tomey).

Toxoplasma gondii infection supports the infiltration of T cells into brain tumors.

Few T cells infiltrate into primary brain tumors, fundamentally hampering the effectiveness of immunotherapy. We hypothesized that Toxoplasma gondii, a microorganism that naturally elicits a Th1 response in the brain, can promote T cell infiltration into brain tumors despite their immune suppressive microenvironment. Using a mouse genetic model for medulloblastoma, we found that T.

Comparative Analysis of the Ultrastructure, Bubble Pores, and Composition of Eggshells of Dwarf Layer-White and Guinea Fowl.

The decrease in eggshell quality seriously affects production efficiency. Guinea fowl (GF) eggs possess strong eggshells because of their unique crystal structure, and few systematic studies have compared laying hen and GF eggs. Sixty eggs were collected from both 40-week-old Dwarf Layer-White (DWL-White) laying hens and GF, and the eggshell quality, ultrastructure, bubble pores, and composition were measured.

iNOS is necessary for GBP-mediated T. gondii clearance in murine macrophages via vacuole nitration and intravacuolar network collapse.

Toxoplasma gondii is an obligate intracellular parasite of rodents and humans. Interferon-inducible guanylate binding proteins (GBPs) are mediators of T. gondii clearance, however, this mechanism is incomplete.

Renin-angiotensin-aldosterone-system inhibitors increase the serum level of complement component 4 in patients with immunoglobulin A nephropathy.

Objective: To investigate the impact of renin-angiotensin-aldosterone-system (RAAS) inhibitors on complement component 4 (C4) serum levels in patients with immunoglobulin A nephropathy (IgAN).

Methods: A total of 423 patients diagnosed with IgAN at Shanxi Provincial People's Hospital, China, between 1 January 2017 and 31 December 2021 were divided into two groups, a RAAS inhibitor group and a non-RAAS inhibitor group, for comparative analysis.

Results: The RAAS inhibitor group exhibited significantly increased C4 and eGFR levels and had a higher proportion of patients with hypertension compared with the non-RAAS inhibitor group.

Inducible nitric oxide synthase (iNOS) is necessary for GBP-mediated restriction in murine macrophages via vacuole nitration and intravacuolar network collapse.

is an obligate intracellular, protozoan pathogen of rodents and humans. ability to grow within cells and evade cell-autonomous immunity depends on the integrity of the parasitophorous vacuole (PV). Interferon-inducible guanylate binding proteins (GBPs) are central mediators of clearance, however, the precise mechanism linking GBP recruitment to the PV and restriction is not clear.

Immunoglobulin G4 in eosinophilic esophagitis: Immune complex formation and correlation with disease activity.

Background: Recent studies have shown deposition of immunoglobulin G4 (IgG4) and food proteins in the esophageal mucosa of eosinophilic esophagitis (EoE) patients. Our aims were to assess whether co-localization of IgG4 and major cow's milk proteins (CMPs) was associated with EoE disease activity and to investigate the proteins enriched in proximity to IgG4 deposits.

Methods: This study included adult subjects with EoE (n = 13) and non-EoE controls (n = 5).

Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in infection-induced cachexia.

Cachexia is a life-threatening disease characterized by chronic, inflammatory muscle wasting and systemic metabolic impairment. Despite its high prevalence, there are no efficacious therapies for cachexia. Mice chronically infected with the protozoan parasite represent a novel animal model recapitulating the chronic kinetics of cachexia.

Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging.

Mitochondrial dysfunction is linked to age-associated inflammation or inflammaging, but underlying mechanisms are not understood. Analyses of 700 human blood transcriptomes revealed clear signs of age-associated low-grade inflammation. Among changes in mitochondrial components, we found that the expression of mitochondrial calcium uniporter (MCU) and its regulatory subunit MICU1, genes central to mitochondrial Ca (mCa) signaling, correlated inversely with age.

Eggshell translucency in late-phase laying hens and its effect on egg quality and physiological indicators.

Eggshell translucency severely affects external egg quality, and variations in the eggshell or eggshell membrane are considered the structural basis of the trait. Research has shown that 1.85% additional mixed fatty acids in the diet would greatly decrease the occurrence of eggshell translucency.

Differential expression and functional analysis of circRNA in the ovaries of Yili geese at different egg-laying stages.

Background: Ovarian development is regulated by genes that are expressed dynamically and stage-specifically. Circular RNA (circRNA) has been proven to play a significant role in the regulation of animal reproduction.

Objective: Studying the expression characteristics of circRNAs in goose ovaries at various egg-laying stages can provide a reference for the molecular regulation mechanism of ovary development in geese that is mediated by circRNAs.

Prognostic value of microRNAs in heart failure: A meta-analysis.

Background: Reported studies have shown that expression levels of microRNAs (miRNAs) are related to survival time of patients with heart failure (HF). A systematic review and meta-analysis were conducted to study circulating miRNAs expression and patient outcome.

Methods: Meta-analysis estimating expression levels of circulating miRNAs in HF patients from January 2010 until June 30, 2018, through conducting online searches in Pub Med, Cochrane Database of Systematic, EMBASE and Web of Science and reviewed by 2 independent researchers.

Discovery of novel aminosaccharide-based sulfonamide derivatives as potential carbonic anhydrase II inhibitors.

In this paper, a new class of novel sulfonamides incorporating aminosaccharide tails were designed and synthesized based on the sugar-tail approach. Then, all the novel compounds were evaluated for their inhibitory activities against three carbonic anhydrase (CA, EC 4.2.

Integrative Analysis of Minichromosome Maintenance Proteins and Their Prognostic Significance in Melanoma.

Background: Minichromosome maintenance () is known for participating in cell cycle progression, as well as DNA replication. While the diverse expression patterns and prognostic values of s in melanoma still remained unclear.

Methods: In the present study, the transcriptional and clinical profiles of s were explored in patients with melanoma from multiple databases, including GEO, TCGA, ONCOMINE, GEPIA, UALCAN, cBioPortal, and TIMER databases.

The Effect of Inclusions on a Medium Temperature Transformation Microstructure and Toughness of High-Strength HSLA Steel.

In this study, the evolution of high-strength HSLA steel microstructure was studied using high-temperature laser confocal microscopy and SEM, TEM, and EPMA techniques. The effect of precipitates on grain boundary migration of austenite during high-temperature heating and the effect of inclusions in undercooled austenite on AF phase transformation were studied. The effect of multiphase microstructure on impact toughness was studied by Gleeble thermal simulation at 550, 600, and 650 °C.

Efficient and selective removal of Congo red by a C@Mo composite nanomaterial using a citrate-based coordination polymer as the precursor.

To research the effect of structural diversity on citrate-based coordination polymers (CPs), citric acid (H4cit) was selected to combine with Cu(ii) under hydrothermal conditions. A new CP [Cu2(cit)(H2O)2] (1) was synthesized and structurally characterized. The title complex shows a 3D 2,4,6-connected topology with the point symbol of {43·63}{44·66·85}{4}.

Overexpression of improves the tolerance of Arabidopsis to salt stress.

Alternative oxidase (AOX) has a well-established involvement in plant growth and stress tolerance in many studies. In this study, we isolated and characterized the AOX2 from . The Open Reading Frame (ORF) contains 1029 nucleotides and encodes 342 amino acid residues.