Synopsis of recent research by authors named "Xiao-yu DU"
- Xiao-yu DU's recent research emphasizes the role of the tumor microenvironment in the efficacy of PD-1 inhibitors for gastric cancer treatment, highlighting ongoing challenges in patient survival despite advances in immunotherapy.
- Investigations into neurodegenerative diseases reveal that DNase II deficiency can lead to neuronal accumulation of double-stranded DNA, which contributes to tau phosphorylation and neurodegeneration, particularly in Alzheimer's disease.
- DU's studies also indicate that mouse serum albumin leakage through the blood-brain barrier exacerbates neurodegenerative conditions by promoting microglia activation and neuronal apoptosis, pointing to potential targets for therapeutic intervention in age-related neuropathology.
