Publications by authors named "Xiao-yan Zhang"

Article Synopsis
  • The study explores the effectiveness of amide proton transfer-weighted (APT) imaging combined with serum squamous cell carcinoma antigen (SCC-Ag) in determining the grading of cervical cancer in 63 patients with confirmed cervical SCC.
  • APT imaging showed strong reproducibility and indicated a significant increase in values across poorly to highly differentiated cancer groups, suggesting it might be a reliable tool for grading the cancer.
  • While SCC-Ag levels also correlated with cancer differentiation, significant differences were only found between certain groups, indicating APT imaging might be more effective for distinguishing between cancer grades.
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  • Observers can estimate the direction of point-light walkers (PLWs) but tend to bias their estimates toward previous directions, showing a serial dependence.
  • The study compared estimations of upright vs. inverted PLWs, finding that inversion decreased accuracy in estimating average directions from multiple PLWs but not for single PLW directions.
  • Results revealed a reference-attraction bias toward a fixed direction (0°) and indicated that presenting multiple PLWs enhanced serial dependence, which was reduced when the PLWs were inverted.
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Studies have found that feature estimates are systematically compressed towards the distribution center, showing a central tendency. Additionally, the estimate of current features is affected by the previously seen feature, showing serial dependence or adaptation effect. However, these all remain unclear in the speed estimation.

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spp. (true morels) are precious edible mushrooms consumed around the world, with a delicious taste, rich nutritional value, and unique healthcare effects. Various fungi and bacteria have been reported to colonize the ascocarps of , damaging their fruiting bodies and leading to serious economic losses in cultivation.

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  • Preoperative prediction of lymphovascular space invasion (LVSI) in cervical cancer is vital for improving patient outcomes, and this study evaluates the effectiveness of combining amide proton transfer (APT) imaging with serum CA125 levels.
  • The study included 80 cervical cancer patients, finding that the APT imaging had an AUC of 0.889 and CA125 levels had an AUC of 0.687 in predicting LVSI.
  • The combination of APT and CA125 showed high diagnostic efficacy, with a sensitivity of 82.7% and specificity of 100%, indicating that this method is a valuable tool for predicting LVSI preoperatively in this patient population.*
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  • * A thorough search of various scientific databases was conducted, including a total of 15 articles that covered over 3,600 glioma cases and nearly 772,000 participants to analyze the data for associations.
  • * The results indicated a significant reduction in glioma risk with higher vitamin C intake (RR = 0.78), while no significant connections were found for vitamin A and vitamin E, highlighting the potential importance of vitamin C in glioma prevention.
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Objectives: To investigate whether high concentration iodinated contrast media (CM), compared with low concentration CM, could reduce pain and discomfort levels in patients who had level II and III venous conditions.

Methods: This prospective, single-center study enrolled patients who had level II and III venous conditions and underwent abdominal contrast-enhanced CT scan between July 2021 and February 2022. The venous condition to establish peripheral venous access for CM injection was graded using the Intravenous Access Scoring system, of which level II and III indicated poor venous condition and difficult venous access.

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  • The study analyzed whether MRI-based radiomics features can effectively predict good response (GR) to neoadjuvant chemoradiotherapy (nCRT) in patients with locally advanced rectal cancer (LARC).
  • Researchers extracted radiomics features from imaging of 1,070 LARC patients and developed models to enhance prediction accuracy, incorporating both radiomic and key clinical MRI features into a combined model.
  • The combined model demonstrated strong predictive capabilities for GR, leading to better disease-free survival outcomes for patients identified as high likelihood for GR, and was validated across multiple datasets with a high-quality score.
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Background: Forest musk deer (FMD, ) is a critically endangered species world-widely, the death of which can be caused by pulmonary disease in the farm. Pulmonary fibrosis (PF) was a huge threat to the health and survival of captive FMD. MicroRNAs (miRNAs) and messenger RNAs (mRNAs) have been involved in the regulation of immune genes and disease development.

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Ectomycorrhizal symbiosis, which involves mutually beneficial interactions between soil fungi and tree roots, is essential for promoting tree growth. To establish this symbiotic relationship, fungal symbionts must initiate and sustain mutualistic interactions with host plants while avoiding host defense responses. This study investigated the role of reactive oxygen species (ROS) generated by fungal NADPH oxidase (Nox) in the development of Laccaria bicolor/Populus tremula × alba symbiosis.

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Nitrofurans are important synthetic broad-spectrum antibacterial drugs with the basic structure of 5-nitrofuran. Due to their toxicity, it is essential to develop a sensitive sensor with strong anti-interference capabilities for their detection. In this work, two {PMoO}-based compounds, [H(HPTTP)]{Cu[MoO(OH)(PO)(HPO)(HPO)]}·HO ( = 13 for (), 7 for (); HPTTP = 4,4',4″,4‴-(1-pyrrole-2,3,4,5-tetrayl)tetrapyridine), exhibiting similar coordination but distinct stacking modes.

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Chronic liver disease (CLD) is a major global health burden in terms of growing morbidity and mortality. Although many conditions can cause CLD, leading to cirrhosis and hepatocellular carcinoma (HCC), viral hepatitis, drug-induced liver injury (DILI), alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are the most common culprits. Prostaglandin E (PGE), produced in the liver, is an important lipid mediator derived from the ω-6 polyunsaturated fatty acid, arachidonic acid, and plays a critical role in hepatic homeostasis.

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Background Detection of extranodal extension (ENE) at pathology is a poor prognostic indicator for rectal cancer, but whether ENE can be identified at pretreatment MRI is, to the knowledge of the authors, unknown. Purpose To evaluate the performance of pretreatment MRI in detecting ENE using a matched pathologic reference standard and to assess its prognostic value in patients with rectal cancer. Materials and Methods This single-center study included a prospective development data set consisting of participants with rectal adenocarcinoma who underwent pretreatment MRI and radical surgery (December 2021 to January 2023).

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Objectives: To analyze the correlation among the imaging features of prostate "nodule in nodule," clinical prostate indices, and pathology results.

Methods: We retrospectively analyzed the prostate images from 47 male patients who underwent MRI scans and pathological biopsy from January 2022 to July 2023. Two radiologists (R1/R2) evaluated the morphology and signal intensity of the "nodule in nodule" in a double-blind manner and calculated the PI-RADS v2.

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Purpose: Rectal tumor segmentation on post neoadjuvant chemoradiotherapy (nCRT) magnetic resonance imaging (MRI) has great significance for tumor measurement, radiomics analysis, treatment planning, and operative strategy. In this study, we developed and evaluated segmentation potential exclusively on post-chemoradiation T2-weighted MRI using convolutional neural networks, with the aim of reducing the detection workload for radiologists and clinicians.

Methods: A total of 372 consecutive patients with LARC were retrospectively enrolled from October 2015 to December 2017.

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Background: In clinical practice, stem cell transplantation has become an effective method for treating spinal cord nerve injury. Up to now, there has been no report on teratoma caused by transplanted stem cell's abnormal differentiation in the clinic, especially in the analysis of imaging manifestations. Therefore, this article aims to analyze the PET/CT imaging manifestations of teratoma caused by stem cell transplantation to improve the imaging diagnosing capability.

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Article Synopsis
  • Around 10%-31% of patients with colorectal liver metastases (CRLM) also have hepatic lymph node metastases (LNM), which often indicates a worse prognosis and complicates surgical options due to a lack of effective preoperative assessment methods.
  • This study aimed to evaluate the effectiveness of different diffusion-weighted imaging (DWI) models in identifying benign versus malignant hepatic lymph nodes in CRLM patients who received neoadjuvant chemotherapy.
  • Results showed that a nomogram based on the DDC value and the size of lymph nodes post-treatment could reliably predict lymph node status, outperforming other methods in distinguishing between benign and malignant cases.
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Background: The use of telemonitoring electrocardiogram (ECG) improves the detection rate of various arrhythmias as it offers an extended recording time and does not impose activity restrictions. However, many community hospitals lack the resources to conduct this test due to a lack of cardiac function specialists and antiquated screening equipment.

Objective: To establish a digital ECG telemonitoring system and remote consultation service between tertiary hospitals and community medical service stations to improve diagnosis and treatment effectiveness.

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  • Wilson disease (WD) is a rare genetic disorder affecting copper metabolism, often leading to cognitive impairments, and the study investigates the neuroprotective potential of chrysophanol (CHR) in this context.
  • Using network pharmacology, researchers identified key target genes and pathways impacted by CHR, particularly focusing on cell apoptosis and the PI3K-AKT signaling pathway.
  • Experimental results indicated that CHR reduces copper levels in the liver, increases its excretion in urine, enhances learning and memory, and positively affects neuron survival in the brain by regulating specific protein expressions related to apoptosis.
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Background: Cow's milk protein allergy (CMPA) is one of the most common types of food allergy in infants. Faecal pathogen cultures showed that the positive rate of Clostridium perfringens was more than 30%, which was significantly higher than that for other bacteria. Therefore, it is speculated that Clostridium perfringens colonization may be one of the pathogenetic factors for CMPA in infants.

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Background: Muscle depletion that impairs normal physiological function in elderly patients leads to poor prognosis. This study aimed to evaluate the association between total abdominal muscle area (TAMA), total psoas area (TPA), psoas muscle density (PMD), and short-term postoperative complications in elderly patients with rectal cancer.

Methods: All elderly patients underwent rectal cancer resection with perioperative abdominal computed tomography (CT).

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A Case of Tuberculosis Cutis Orificialis.

Clin Cosmet Investig Dermatol

September 2023

This work reports a case of a 49-year-old male suffering from chronic tuberculosis who developed painful ulcers around the anus for approximately eight months. The colonoscopy revealed the presence of ulcers in the transverse colon, which were also found in the skin and intestine, as revealed by microscopic examination. The skin ulcer was positive for tuberculosis bacilli, leading to the final diagnosis of Tuberculosis cutis orificialis.

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Background: Our previous study has revealed that EphA7 was upregulated in patient-derived esophageal squamous cell carcinoma (ESCC) xenografts with hyper-activated STAT3, but its mechanism was still unclear.

Materials And Methods: To assess the association between EphA7 and STAT3, western blotting, immunofluorescence, ChIP assay, and qRT-PCR were conducted. Truncated mutation and luciferase assay were performed to examine the promoter activity of EphA7.

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W.T. Wang 1980 is an important traditional medicinal plant used for the treatment of cardiac diseases.

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Introduction: Incidences of stroke are on the rise and approximately 80 million stroke survivors worldwide live with disabilities. Supportive care needs of stroke survivors are not adequately defined, and the assessment tools to help care service providers identify these needs are unclear. The overall aim of this scoping review will be to map the supportive care needs of stroke survivors against the Supportive Care Needs Framework.

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