[Synergistic Emission Reduction of Carbon Dioxide and Atmospheric Pollutants Under Different Low-carbon Development Scenarios of the Power Industry in Jiangsu Province].

The power industry is the main source of carbon dioxide （CO） emissions in Jiangsu Province and also an important source of sulfur dioxide （SO）, nitrogen oxides （NO）, and particulate matter （PM）. In order to address climate change and contribute to the goal of "carbon peaking and carbon neutrality," Jiangsu Province has implemented a series of low-carbon development policies in the power industry. These policies not only reduce carbon emissions but also have important synergistic emission reduction benefits for atmospheric pollutants.

Clinical application value of long non-coding RNAs signatures of genomic instability in predicting prognosis of hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) presents challenges due to its high recurrence and metastasis rates and poor prognosis. While current clinical diagnostic and prognostic indicators exist, their accuracy remains imperfect due to their biological complexity. Therefore, there is a quest to identify improved biomarkers for HCC diagnosis and prognosis.

[Coordinated Control of Carbon Emission Reduction and Air Quality Improvement in the Industrial Sector in Hunan Province].

Climate warming and air pollution are the main environmental problems in China. This study used China's Carbon Accounting Database, energy economic model, and air quality model to analyze the potential carbon emission peaking path and synergistic air quality improvement gain in the industrial sector in Hunan Province. Based on China's Carbon Accounting Database and the local industry/energy statistical yearbooks in Hunan, the total CO emissions in Hunan Province in 2019 were 310.

Preventive effect of crocin on osteoporosis in an ovariectomized rat model.

The purpose of this study was to investigate the therapeutic effects of crocin on ovariectomy-induced osteoporosis in rats. Female Sprague-Dawley rats were randomly assigned to a sham-operated group (sham) and five ovariectomy (OVX) subgroups, that is, OVX with vehicle (OVX), OVX with 17β-estradiol (E 2, 25 μg/kg/day), and OVX with graded crocin doses (5, 10, or 20 mg/kg/day). Daily oral administration of E 2 or crocin started 4 weeks after OVX and lasted for 16 weeks.

Downregulation of HDAC1 is involved in the cardiomyocyte differentiation from mesenchymal stem cells in a myocardial microenvironment.

Under myocardial microenvironment, bone marrow-derived mesenchymal stem cells (MSCs) can transdifferentiate into cardiomyocytes (CMs). However, the role of histone deacetylase 1 (HDAC1) in this directed differentiation process remains unclear. The current study is to determine the acetylation regulatory mechanisms that may be involved in the directed CM differentiation from MSCs.

Knockdown of the HDAC1 promotes the directed differentiation of bone mesenchymal stem cells into cardiomyocytes.

Failure of the directed differentiation of the transplanted stem cells into cardiomyocytes is still a major challenge of cardiac regeneration therapy. Our recent study has demonstrated that the expression of histone deacetylase 1 (HDAC1) is decreased in bone mesenchymal stem cells (BMSCs) during their differentiation into cardiomyocytes. However, the potential roles of HDAC1 in cardiac cell differentiation of BMSCs, as well as the mechanisms involved are still unclear.

[Protective effects of estrogen on mitochondria in human umbilical vascular endothelial cells].

Objective: To investigate the protective effects of estrogen on the mitochondria in human umbilical vascular endothelial cells (HUVECs).

Methods: HUVECs were exposed to H2O2 at 250 micromol/L for 4 h with or without pretreatment with 17-estradiol (E2) and ICI182780. Complex IV activity of the cells was measured with chromometry, and 2, 7-dichlorofluorescein diacetate (DCFH-DA) was used to determine intracellular reactive oxygen species (ROS).

Effects of testosterone on cytokines and left ventricular remodeling following heart failure.

Aims: To investigate the effects of testosterone treatment on cytokines, ventricular remodeling in rats with heart failure.

Materials And Methods: Sprague-Dawley male rats with heart failure were divided into testosterone (n = 22) and placebo (n = 22) group. Pseudo surgery was performed on a third group of 15 male rats as control.

[Experimental study of the characteristics of renal blood flow with contrast ultrasound].

Objective: To study the characteristics of renal blood flow with contrast ultrasound.

Methods: The examination of the renal ultrasonography was performed in 10 dogs after intravenous injection of Quanfuxian (a contrast agent consisting of C3F8 microbubbles).

Results: Contrast visualization appeared in the renal cortex and then in the outer to inner medulla at the baseline level after administration of the contrast agent.

[Quantification of renal medullary perfusion with contrast-enhanced ultrasound: an experimental study].

Objective: To quantitatively evaluate the effects of dopamine (DA) and noradrenaline (NE) on renal medullary perfusion and the differences in perfusion in the outer and inner medulla using contrast-enhanced ultrasound.

Methods And Results: Contrast-enhanced ultrasound was performed in 10 dogs with simultaneous renal artery flow (RAF) measurement at the baseline level and during application of 3 different doses of DA and NE. During treatment with the 3 doses of DA, the changes of ultrasound-derived parameters (A, beta and A*beta) in the medulla were similar to the changes in the cortex.

[Quantitative evaluation of canine renal blood flow with contrast-enhanced ultrasound].

Objective: To evaluate the accuracy of contrast-enhanced ultrasound (CEU) in renal blood flow quantification.

Methods: Regional renal perfusion was quantified with CEU in 10 dogs at the baseline level and after treatment with 3 doses of dopamine (3, 8 and 16 mg.kg(-1).

[Effects of a novel recombinant polypeptide from the sea anemone Anthopleura sp. on left ventricular function in dogs with acute cardiac insufficiency].

Objective: To observe the effects of recombinant hk2a, a novel neurotoxin from the sea anemone Anthopleura sp., on left ventricular function of dogs with acute cardiac insufficiency.

Methods: Canine models of acute cardiac insufficiency were established by rapid ventricular pacing, in which the left ventricular ejection fraction (LVEF) was measured by Acuson ultrasound systems (Sequoia 512) at 0, 5, 15, 30 and 60 min, respectively, after intravenous injection of 30 microg/kg recombinant hk2a.

[Effects of blood lipid levels on ST-T segment in asymptomatic hypertensive patients].

Objective: To identify the factors affecting ST-T segment in asymptomatic hypertensive patients.

Methods: The asymptomatic patients with hypertension were divided into abnormal ST-T group (n=28) and normal ST-T group (n=20), in whom the serum levels of glucose, total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), very-low-density lipoprotein cholesterol (VLDL) were measured.

Results: Compared with patients with normal ST-T segment, patients with abnormal ST-T segment had significantly higher serum levels of TC, but significantly lower HDL.