Nonreciprocal -symmetric magnon laser in spinning cavity optomagnonics.

We propose a scheme to achieve nonreciprocal parity-time ( )-symmetric magnon laser in a -symmetric cavity optomagnonical system. The system consists of active and passive optical spinning resonators. We demonstrate that the Fizeau light-dragging effect induced by the spinning of a resonator results in significant variations in magnon gain and stimulated emitted magnon numbers for different driving directions.

Hepatic vagotomy blunts liver regeneration after hepatectomy by downregulating the expression of interleukin-22.

Background: Rapid regeneration of the residual liver is one of the key determinants of successful partial hepatectomy (PHx). At present, there is a lack of recognized safe, effective, and stable drugs to promote liver regeneration. It has been reported that vagus nerve signaling is beneficial to liver regeneration, but the potential mechanism at play here is not fully understood.

Parametrically amplified nonreciprocal magnon laser in a hybrid cavity optomagnonical system.

We propose a scheme to achieve a tunable nonreciprocal magnon laser with parametric amplification in a hybrid cavity optomagnonical system, which consists a yttrium iron garnet (YIG) sphere and a spinning resonator. We demonstrate the control of magnon laser can be enhanced via parametric amplification, which make easier and more convenient to control the magnon laser. Moreover, we analyze and evaluate the effects of pump light input direction and amplification amplitude on the magnon gain and laser threshold power.

[Effects of Notch-1/Twist-1 axis in the process of epithelial-mesenchymal transition of type II alveolar epithelial cell and its mechanism].

To study the role of Notch-1/Twist-1 axis in the process of epithelial-mesenchymal transition (EMT) of type II alveolar epithelial cells in pulmonary fibrosis (PF) and hope to provide a new theoretical basis for the pathogenesis of PF. Thirty rats were randomly divided into control group and bleomycin (BLM) group, 15 rats in each group. The PF rat model was induced by intratracheal injection of BLM (7 500 U/kg).

Hb Hezhou [β64(E8)Gly→Ser; : c.193G>A]: A Novel Variant on the β-Globin Gene.

We report a novel mutation on the β-globin gene, Hb Hezhou [β64(E8)Gly→Ser; : c.193G>A] that was detected in two unrelated Chinese individuals. Patient 1 also carried an α-thalassemia (α-thal) -α (leftward) deletion, but hematological analyses showed no clinical consequences.

[Chrysin inhibited epithelial-mesenchymal transition of type Ⅱ alveolar epithelial cell by regulating NF-κB/Twist 1 signaling pathway].

This study aimed to assess whether chrysin(ChR) can inhibit epithelial-mesenchymal transition(EMT) of type Ⅱ alveolar epithelial cell and produce anti-pulmonary fibrosis effect by regulating the NF-κB/Twist 1 signaling pathway. Sixty rats were randomly divided into the control group, the bleomycin(BLC) group, BLC+ChR(50 mg·kg~(-1)) group and BLC+ChR(100 mg·kg~(-1)) group, with 15 rats in each group. The pulmonary fibrosis model was induced by intratracheal injection of BLC(7 500 U·kg~(-1)).

[Effect of small dose capsaicin for treatment of pulmonary fibrosis in mice and its mechanism].

To observe whether the mechanism of small dose capsaicin (Cap) against pulmonary fibrosis in mouse is mediated by agitating transient receptor potential vanilloid 1 (TRPV1). Methods: A total of 60 BALB/c mice were randomly divided into control (CON) group, bleomycin (BLM)group, Cap (0.5, 1,2 mg/kg) groups and Cap (2 mg/kg) plus SB-452533 (2.

US-guided microwave ablation for primary hyperparathyroidism: a safety and efficacy study.

Objectives: To evaluate the safety and efficacy of microwave ablation (MWA) with the assistance of continuous cool saline injection (CCSI) in patients with primary hyperparathyroidism (PHPT).

Methods: Between November 1, 2014, and February 29, 2016, 22 patients with PHPT were enrolled and treated with ultrasound-guided MWA assisted by CCSI. The levels of parathyroid hormone (PTH) and serum calcium were recorded before and after the MWA.

[Effects of EGCG on Proliferation, Cell Cycle and DAPK1 Gene Methylation of Acute Promyelocytic Leukemia NB4 Cell Line].

Objective: To investigate the effects of epigallocatechin-3-gallate (EGCG) on proliferation and cell cycle of acute promyelocytic leukemia NB4 cell line and to clarify the molecular mechanism.

Methods: NB4 cells were treated with 0,50,75,100 and 125µmol/L of EGCG for 24, 48, 72 and 96 h, respectively. The proliferation level of NB4 cells was measured by CCK-8 assay.

[Effects of Aquaculture on Ammonia-oxidizing Prokaryotes in Sediments of Eastern Lake Taihu].

The abundance and diversity of ammonia-oxidizing microorganisms in sediments of an aquacultural area of Eastern Lake Taihu were investigated. Real-time quantitative PCR was used to analyze the abundance of archaeal and bacterial genes. Cloned libraries were constructed to investigate the structure and diversity of the microbial community.

[Effects of Optimized Fish Farming on the Sediment Nutrients of Eastern Lake Taihu].

The farming of lake fisheries is an important part of the freshwater fishery industry in China. However, farming patterns of traditional fisheries maintain serious negative effects on the ecosystem of Eastern Lake Taihu. In recent years, the enclosure culture model of this lake has been optimized.

Identification of bioactives from L.f. and their antioxidant, anti-inflammatory and anti-proliferative effects.

This work was designed to obtain the valuable compounds with antioxidant, anti-proliferative and anti-inflammatory activities from . Ethyl acetate fraction obtained from L.f.

[Pharmacokinetics and brain distribution of NMD/TMP-nanoparticles].

This study aims to prepare nimodipine/tetramethylpyrazine-loaded poly(D, L-lactide-co-glycolide) dual-drug nanoparticles (NMD/TMP-NPs) and investigate pharmacokinetics and brain distribution to evaluate the possibility of enhancing the drug effect of dual-drug nanoparticles. NMD/TMP-NPs were prepared via W/O/W emulsion solvent evaporation. Entrapment efficiency and drug loading of NMD/TMP-NPs were investigated by ultracentrifugation, and drug release behavior in vitro was studied by dialysis method.

Effects of adding corn oil and soy protein to corn starch on the physicochemical and digestive properties of the starch.

This study aimed to understand effects of adding corn oil (CO) and soy protein (SP) to corn starch on the physicochemical properties and digestive rates of annealed starch complex and mechanisms of interactions between corn starch (CS), CO and SP. Binary and ternary blends were prepared using CS mixed with CO (10%, dsb) and/or SP (10%, dsb) and incubated in a water bath at 50°C for 14h. Results showed that more agglomerates of the granules were in the ternary blends.

Effect of dobutamine on lung aquaporin 5 in endotoxine shock-induced acute lung injury rabbit.

Background: Dobutamine, a commonly used vasoactive drug, has been reported to reduce pulmonary edema and protect against acute lung injury (ALI) by up-regulating aquaporin 5 (AQP5) expressions. However, the underlying mechanism is still elusive.

Methods: ALI was induced by intravenous injection of LPS.

[Effect of As₂O₃on Hedgehog Pathway in Chronic Myeloid Leukemia Cells].

Objective: To explore the effect of As₂O₃on Hedgehog pathway in chronic myeloid leukemia (CML) cells.

Methods: The apoptosis of K562 cells was detected by MTT method and flow cytometry; the expressions of PTCH and SMO protein and mRNA in Hedgehog pathway were determined by Western blot and real-time PCR, respectively. Retults: The As₂O₃ could induce the apoptosis of K562 cells with optimal concentration 2 µmol/L and optimal time 24 hours.

Functional analyses on antioxidant, anti-inflammatory, and antiproliferative effects of extracts and compounds from Ilex latifolia Thunb., a Chinese bitter tea.

Ilex latifolia Thunb., widely distributed in China, has been used as a functional food and drunk for a long time. This study was aimed to identify the bioactive constituents with antioxidant, antitumor, and anti-inflammatory properties.

Efficacy evaluation of a Chinese bitter tea (Ilex latifolia Thunb.) via analyses of its main components.

In order to evaluate the health effects of Ilex latifolia Thunb., a Chinese bitter tea widely consumed as a health beverage, flavonoids, saponins, polysaccharides and alkaloids were extracted from its leaves and their in vitro antioxidant activity, anticomplement system activity, antiproliferative effects against human cervical carcinoma Hela cells, and anti-inflammatory effects against mouse macrophage RAW 264.7 cells were analyzed.

Hydroxytyrosol and its potential therapeutic effects.

As olive oil is the main source of calories in the Mediterranean diet, a large number of studies have been carried out to characterize its role in various diseases and exploitation for the prevention and treatment of hypertension, carcinogenesis, diabetes, atherosclerosis, and other diseases. As one of the major polyphenols present in virgin olive oil, hydroxytyrosol shows a variety of pharmacological activities such as antioxidant properties, anticancer, anti-inflammatory, and neuroprotective activities, and beneficial effects on the cardiovascular system, which show its potentiality for the development of dietary supplements. In the future, more attention should be paid to its action mechanism in vivo and synergistic effect.

The mechanism of starch granule reacted with OSA by phase transition catalyst in aqueous medium.

The reactivity of octenyl succinic anhydride (OSA) with starch by phase transition catalyst (PTC) was investigated. The effects of two types (quaternary ammonium salt and non-ionic surfactant) and concentrations of PTC on the degree of substitution (DS) and reaction efficiency (RE) of OS-starch were examined. In aqueous medium, the use of a PTC, polyoxyethylene lauryl ether (AEO) produced derivatives with higher DS than others.

Vimentin significantly promoted gallbladder carcinoma metastasis.

Background: The precise molecular mechanisms underlying the gallbladder carcinoma (GBC) metastasis has not been fully elucidated.

Methods: In the present study, metastasis-associated proteins were identified by comparative proteomic analysis. The functional study of the candidate protein vimentin was further investigated.

[Establishment and characterization of serial subpopulations with highly metastatic potential via different metastatic routes].

Objective: To establish the serial cell lines, derived from the same parental gallbladder cancer cell line GBC-SD, with highly metastatic potential via different routes and characterize their biological behaviors to understand the different metastasis mechanisms via lymph and blood.

Methods: The spleen-liver metastasis model and footpad-inguinal lymph node metastasis model were established. GBC-SD was injected into spleen or footpad of nude mice.

Root hair-specific expansins modulate root hair elongation in rice.

Root hair growth requires intensive cell-wall modification. This study demonstrates that root hair-specific expansin As, a sub-clade of the cell wall-loosening expansin proteins, are required for root hair elongation in rice (Oryza sativa L.).

Expression of the Arabidopsis thaliana histone gene AtHTA1 enhances rice transformation efficiency.

We expressed the Arabidopsis thaliana histone AtHTA1 in rice under the control of the maize ubiquitin promoter. Transformation efficiencies of rice plants that constitutively expressed AtHTA1 were 28-44% higher than calli containing an empty vector control. Furthermore, co-infection of rice calli with a vector containing AtHTA1 and another vector with the target gene increased transformation by 27-50%.