Publications by authors named "Xiao-peng Yan"

Background: The treatment of postoperative anastomotic stenosis after excision of rectal cancer is challenging. Endoscopic balloon dilation and radial incision are not effective in all patients. We present a new endoscopy-assisted magnetic compression technique (MCT) for the treatment of rectal anastomotic stenosis.

View Article and Find Full Text PDF

Background: The combination of magnetic compression anastomosis (MCA) and endoscopy has been used to treat biliary stricture after liver transplantation. However, its use for the treatment of complex biliary obstruction after major abdominal trauma has not been reported. This case report describes the successful use of MCA for the treatment of biliary obstruction resulting from major abdominal trauma.

View Article and Find Full Text PDF

Natural environments play a crucial role in transmission of antimicrobial resistance (AMR). Development of methods to manage antibiotic resistance genes (ARGs) in natural environments are usually limited to the laboratory or field scale, partially due to the complex dynamics of transmission between different environmental compartments. Here, we conducted a nine-year longitudinal profiling of ARGs at a watershed scale, and provide evidence that restrictions on livestock farms near water bodies significantly reduced riverine ARG abundance.

View Article and Find Full Text PDF
Article Synopsis
  • Postoperative anastomotic stenosis (AS) after colorectal cancer surgery can be difficult to treat, with endoscopic balloon dilation sometimes being ineffective for certain patients.
  • A 72-year-old man, who had undergone a radical resection and ileostomy closure, experienced persistent AS despite multiple balloon dilation attempts.
  • Magnetic compression technique (MCT) successfully treated the stenosis, indicating it as a viable minimally invasive option for managing AS after colorectal cancer procedures.*
View Article and Find Full Text PDF

Background: Magnetic anchor technique (MAT) has been applied in laparoscopic cholecystectomy and laparoscopic appendectomy, but has not been reported in laparoscopic partial hepatectomy.

Aim: To evaluate the feasibility of the MAT in laparoscopic left lateral segment liver resection.

Methods: Retrospective analysis was conducted on the clinical data of eight patients who underwent laparoscopic left lateral segment liver resection assisted by MAT in our department from July 2020 to November 2021.

View Article and Find Full Text PDF

Background: The magnetic compression technique has been used to establish an animal model of tracheoesophageal fistula (TEF), but the commonly shaped magnets present limitations of poor homogeneity of TEF and poor model control. We designed a T-shaped magnet system to overcome these problems and verified its effectiveness animal experiments.

Aim: To investigate the effectiveness of a T-shaped magnet system for establishing a TEF model in beagle dogs.

View Article and Find Full Text PDF

Background: Despite much work having been conducted on magnetic compression anastomosis (MCA) in the digestive tract, there are no reports on the influence of magnetic force on the anastomosis.

Aim: To investigate the effect of different magnetic force magnets on the MCA of the digestive tract.

Methods: Two groups of magnets of the same sizes but different magnetic forces were designed and produced.

View Article and Find Full Text PDF

Background: Treatment of postoperative anastomotic stenosis for colorectal cancer is often challenging, especially for patients who do not respond well to endoscopy. In cases where patients have undergone an enterostomy, the stenosis can be easily resolved through magnetic compression. However, common magnetic compression techniques cannot be performed on those without enterostomy.

View Article and Find Full Text PDF

Background: Endoscopic balloon dilation is a minimally invasive treatment for colorectal stenosis. Magnetic compression anastomosis can be applied against gastrointestinal anastomosis. When combined with endoscopy, it offers a unique approach to the recanalization of colorectal stenosis.

View Article and Find Full Text PDF

Background: Gastric cancer (GC) has high morbidity and mortality. Moreover, because GC has no typical symptoms in the early stages, most cases are already in the advanced stages by the time the symptoms appear, thus resulting in poor prognosis and a low survival rate. Endoscopic submucosal dissection (ESD) can realize the early detection and diagnosis of GC and become the main surgical method for early GC.

View Article and Find Full Text PDF

Background: Esophageal cancer has high incidence globally and is often diagnosed at an advanced stage. With the widespread application of endoscopic technologies, the need for early detection and diagnosis of esophageal cancer has gradually been realized. Endoscopic submucosal dissection (ESD) has become the standard of care for managing early tumors of the esophagus, stomach, and colon.

View Article and Find Full Text PDF

Background: Although endoscope-assisted magnetic compression anastomosis has already been reported for colonic anastomosis, there is no report on a single-approach operation using the natural orifice.

Aim: To design a deformable self-assembled magnetic anastomosis ring (DSAMAR) for colonic anastomosis for use in single-approach operation and evaluate its feasibility and safety through animal experiments.

Methods: The animal model for colonic stenosis was prepared by partial colonic ligation in eight beagles.

View Article and Find Full Text PDF

Background: Biliary adenomas that occur in the extrahepatic biliary tree are rare. It is difficult to distinguish it from cholangiocarcinoma or cholangiolithiasis by various imaging examinations, and it is very easy to be misdiagnosed.

Aim: To evaluate the cumulative experiences including clinical characteristics and treatments of nine patients diagnosed with extrahepatic biliary adenoma admitted to the First Affiliated Hospital of Xi'an Jiaotong University from 2016 to 2022.

View Article and Find Full Text PDF

Background: Magnetic compression anastomosis (MCA) is a simple procedure contributing to a reliable anastomosis. However, digestive-tract reconstruction after total gastrectomy using MCA has not yet been reported.

Aim: To investigate the feasibility of MCA for simultaneous esophagojejunostomy and jejunojejunostomy after total gastrectomy using beagle dogs.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers developed a new device called the Y-Z magnetic hepatic portal blocking band (Y-Z MHPBB) to improve surgical procedures by reducing liver bleeding during liver removal surgery (hepatectomy).
  • In a study with ten beagles, the Y-Z MHPBB was tested against a control group, focusing on operation time, blood loss, and efficiency in using the device for occluding blood flow.
  • Results indicated that while both groups performed similarly in terms of surgery duration and blood loss, the Y-Z MHPBB showed significantly better time efficiency and flexibility compared to the traditional device, suggesting it is a promising tool for surgical use.
View Article and Find Full Text PDF
Article Synopsis
  • The study introduces a new magnetic gel for locating small pulmonary nodules in a rabbit model, aiming to improve safety and success rates compared to existing methods.
  • The gel, made from sodium alginate-FeO magnetic fluid and calcium gluconate, was injected into the lungs either during surgery or under X-ray guidance, and its location could be monitored using a magnetic attractor.
  • Results showed no complications, a stable formation of the gel, and clear boundaries in tissue analysis, suggesting that this technique is both safe and effective for future applications in locating pulmonary nodules.
View Article and Find Full Text PDF

Purpose: The magnetic compression technique (MCT) is a new surgical method that has been used for gastrointestinal anastomosis, choledochojejunostomy, and intestinal anastomosis, but there are no reports on its use for esophagogastric anastomosis. This study aimed to investigate the feasibility of using MCT to fashion esophagogastric anastomoses in rabbits.

Methods: Twenty rabbits were randomized into an MCT group (study group, n = 10) and a hand-sewn group (control group, n = 10).

View Article and Find Full Text PDF

Background: Programmed death- ligand 1 (PD-L1) seems to be associated with the immune escape of tumors, and immunotherapy may be a favorable treatment for PD-L1-positive patients. We evaluated intrahepatic cholangiocarcinoma (ICC) specimens for their expression of PD-L1, infiltration of CD8+ T cells, and the relationship between these factors and patient survival.

Methods: In total, 69 resections of ICC were stained by immunohistochemistry for PD-L1, programmed death factor-1 (PD-1), and CD8+ T cells.

View Article and Find Full Text PDF

Magnetic compression anastomosis (MCA) has been appreciated as an innovative alternative to manual suturing in vascular reconstruction. However, magnetic devices have limitations in their applications. The present study aimed to introduce a newly developed magnetic device for end-to-end vascular anastomosis.

View Article and Find Full Text PDF

The present study aimed to investigate the long-term and perioperative outcomes of precise hepatic pedicle dissection in anatomical resection (precise AR) vs non-anatomical resection (NAR) for hepatocellular carcinoma (HCC) patients.Data from a total of 270 consecutive HCC patients who underwent curative hepatectomy were retrospectively collected. Propensity score matching (PSM) analysis was performed.

View Article and Find Full Text PDF

Background: Clinically, tracheoesophageal fistula (TEF) is lack of effective surgical strategies. One reason is due to the lack of appropriate animal models of acquired TEF, which is usually complex and difficult. Recently, the magnetic compression technique has been applied for digestive tract anastomosis or vascular anastomosis in animals.

View Article and Find Full Text PDF

Background And Aim: Magnetic anastomosis has been attempted in biliary and intestinal reconstruction. The objective of the current study was to introduce an initial clinical use of magnetic compression anastomosis for pancreaticojejunostomy and biliojejunostomy in Whipple's procedure.

Methods: Patients with peri-ampullary carcinoma and dilated bile and pancreatic ducts were prospectively enrolled from 2016 to 2017.

View Article and Find Full Text PDF

Purpose: This study evaluated a novel magnetic compression technique (magnamosis) for creating a portacaval shunt in a canine model of portal hypertension, relative to traditional manual suture.

Methods: Portal hypertension was induced in 18 dogs by partial ligation of the portal vein (baseline). Six weeks later, extrahepatic portacaval shunt implantation was performed with either magnetic anastomosis rings, or traditional manual suture (n = 9, each).

View Article and Find Full Text PDF

Background: Magnetic compression anastomosis (magnamosis, MCA) has been verified safe and effective by us and others in animal bilioenteric anastomosis (BEA). The objective of the present study was to introduce clinical application of magnetic compression bilioenteric anastomosis (MC-BEA) with a unique device in series of patients.

Methods: Patients with obstructive jaundice with an indication of BEA were prospectively enrolled from 2012 to 2015.

View Article and Find Full Text PDF