FOXO1 and hsa-microRNA-204-5p affect the biologic behavior of MDA-MB-231 breast cancer cells.

RNA molecules and targeting microRNA (miRNA) have been reported as novel focuses in recent research on breast cancer. This study aimed to probe the expression of FOXO1 in the MDA-MB-231 cell line and to explore the target effects of FOXO1 with hsa-microRNA-204-5p (miR-204) on the biologic behavior of MDA-MB-231 cells. The expression of FOXO1 mRNA and protein in MDA-MB-231 cells were derived and verified from the public databases, literature, and experimental assays, then the downregulation of FOXO1 was confirmed in the MDA-MB-231 cell line.

[Efficacy comparision of lumbar disc herniation treated with acupuncture at different time intervals].

Objective: To observe the effect of lumbar disc herniation treated with acupuncture at different time intervals.

Methods: A total of 180 patients of lumbar disc herniation were randomized into an observation group 1, an observation group 2 and an observation group 3, 60 cases in each one. All patients were treated with acupuncture at Jiaji L-L (EX-B 2), Huantiao (GB 30), Weizhong (BL 40), etc.

miR-204 regulates the biological behavior of breast cancer MCF-7 cells by directly targeting FOXA1.

MicroRNAs (miRNAs) are short, non-protein-coding RNAs and transcripts that are 18-24 nt in length. miR-204 was first identified as an anti-oncogene and is reported to be downregulated in non-small cell lung cancer, glioma, gastric and thyroid cancer. Recent studies have proposed that a low level of miR-204 expression is associated with tumor progression and disease outcome in breast cancer.

[Investigation on the source of infection regarding an avian influenza (H5N1) case in Hong Kong that returning from Guangzhou].

Objective: We conducted an epidemiologic investigation to determine the source of infection on an avian influenza (H5N1) case who returned from Guangzhou, in Hong Kong.

Methods: Data related to epidemiologic investigation, medical observation on close contacts, Syndromic Surveillance on poultry salesmen, emergency monitoring, detection of the samples, source tracing on potential Avian influenza virus (H5, H7, H9) infected people, situation on environment pollution by avian influenza virus in the markets etc. were gathered.

Improved kinetics of LiNi(1/3)Mn(1/3)Co(1/3)O2 cathode material through reduced graphene oxide networks.

An electronically conducting 3D network of reduced graphene oxide (RGO) was introduced into LiNi(1/3)Mn(1/3)Co(1/3)O(2) (LNMC) cathode material in a special nano/micro hierarchical structure. The rate test and cycling measurement showed that the hierarchical networks remarkably improve the high rate performance of LNMC electrode for lithium-ion batteries. The effect of RGO conducting networks on kinetic property was investigated by electrochemical impedance spectroscopy (EIS) and potentiostatic intermittent titration (PITT).

[Investigation on a seasonal influenza accompanying with the first locale novel A/H1N1 influenza outbreak in China].

Objective: To timely summarize past experience and to provide more pertinent reference for control and prevention in A/H1N1 cases in influenza season.

Methods: During May 25 to 31, 2009, 2 secondary community cases caused by a influenza A/H1N1 imported case. In the close contacts of 3 A/H1N1 cases, 14 had some aspirator symptoms onset, such as fever (> or = 37.

[Epidemiological characteristic of first case of locally identified A/H1N1 secondary cases caused by imported source of infection in China].

Objective: To study the first locally identifed A/H1N1 secondary cases outbreak in China.

Methods: Interview and field investigation were integrated to describe the whole process of transmission on each case and to illustrate the relationships between the onset of the disease and the retated factors.

Results: Two contact persons appearanced fever and whose throat swabs were tested positive to H1N1 viral nucleic acid.

[Comparison of therapeutic effects of electroacupuncture treatment of insomnia at different time].

Objective: To compare the therapeutic effects of evening-electroacupuncture (EA) and morning-EA for insomnia.

Methods: Sixty cases of simple insomnia patients were randomly divided into evening-EA group and morning-EA group, with 30 cases in each. EA (2/100 Hz, 1-3 mA) was applied to Baihui (GV 20), Shenting (GV 24), Touwei (ST 8), Shenmen (HT 7), Sanyinjiao (SP 6), etc.