Publications by authors named "Xiao-li Ma"

Nonalcoholic fatty liver disease is a complex disease involving abnormal liver metabolism. Its strong association with metabolic dysfunction has led to a change in nomenclature to metabolism dysfunction-associated fatty liver disease (MAFLD). MAFLD pathogenesis involves abnormal accumulation of hepatic lipids that lead to the production of excess free fatty acids (FFAs), which in turn cause an imbalance in hepatic mitochondrial function.

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Background: The diagnosis and treatment of depression in patients with chronic heart failure (CHF) is challenging, with no ideal treatment at present.

Aim: To analyze the clinical intervention effect of Xuefu Zhuyu decoction (XFZYD) on CHF complicated with depression.

Methods: The study cohort comprised 116 patients with CHF complicated with depression who received treatment from July 2020 to July 2023, of which 55 received Western medicine (control group) and 61 received XFZYD (research group).

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  • The article with DOI: 10.3892/etm.2020.8623 has been officially retracted.
  • This means that the information or findings presented in that article are no longer considered valid or reliable.
  • Retractions typically occur due to issues like errors, ethical concerns, or misconduct in the research.
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  • * The structures of these compounds were determined using advanced spectroscopic methods, including NMR and mass spectrometry.
  • * The new compounds demonstrated significant inhibitory effects on HepG2 cancer cells, with IC values comparable to the positive control cisplatin, indicating potential for cancer treatment.
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Four previously undescribed diastereomeric lignan glycosides, namely cistadesertosides B-E (1-4) were isolated from the stems of cultural Cistanche deserticola in Tarim desert. The structures of these compounds were elucidated on the basis of extensive spectroscopic analyses, including IR, HR-ESI-MS, 1D and 2D NMR, circular dichroism (CD) data and chemical degradation. The in vitro anti-inflammatory activity of the isolates was also investigated.

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  • * Advanced techniques like IR, NMR, and ECD calculations were used to determine the structures of these compounds.
  • * The compounds were tested for their effects on cancer cell growth, revealing that some, particularly compounds 7 and 15, had strong inhibitory effects on A549 cells, while others showed varying levels of activity against H1299 and HepG2 cancer cells.
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Background: More efficient instruments for body constitution identification are needed for clinical practice. We aimed to develop the short-form version of the Constitution in Chinese Medicine Questionnaire (CCMQ) and evaluate for health management.

Methods: First, the short forms were developed through expert survey, classical test theory (CTT), and modern item response (IRT) based on the CCMQ.

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  • Researchers studied survival chances for Chinese kids with a type of liver cancer called hepatoblastoma and looked at a new treatment from 2016.
  • They found that most kids (93.5%) survived well after four years, and younger kids or those without advanced cancer had the best chances.
  • The results showed that if kids had a big drop in a specific blood marker, they tended to do even better after treatment.
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Microscopy is being pursued to obtain richer and more accurate information, and there are many challenges in imaging depth and display dimension. In this paper, we propose a three-dimensional (3D) microscope acquisition method based on a zoom objective. It enables 3D imaging of thick microscopic specimens with continuous adjustable optical magnification.

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It is essential to understand the occurrence from and plant bioavailability of soil microplastics to heavy metals in soils to assess their environmental fate and risk. The purpose of this study was to evaluate the effect of different microplastic concentrations on the bioavailability of copper and zinc in soil. The relationship between the availability of heavy metals in soil assessed by chemical methods (soil fractionation) and the bioavailability of copper and zinc assessed by biological methods (accumulation in maize and cucumber leaves) in relation to the concentration of microplastics.

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Background: Angiosarcoma is a highly malignant soft-tissue sarcoma derived from vascular endothelial cells that mainly occurs in the skin and subcutaneous tissues. Small-intestinal angiosarcomas are rare, and the prognosis is poor.

Case Summary: We reported a case of primary multifocal ileal angiosarcoma and analyze previously reported cases to improve our understanding of small intestinal angiosarcoma.

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Depth of field (DOF) and resolution are mutually restricted in integral imaging (II) display. To overcome the trade-offs, we propose an II display system that simultaneously enhances the DOF and resolution. The system consists of a transmissive mirror device (TMD), a semi-transparent mirror (STM), and two II display units.

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Multiple myeloma (MM) is one of the most common tumors of the hematological system and remains incurable. Recent studies have shown that long noncoding RNA NORAD is a potential oncogene in a variety of tumors. However, the general biological role and clinical value of NORAD in MM remains unknown.

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We propose a system to eliminate the graininess of an integral imaging 3D display by using a transmissive mirror device (TMD). The proposed system consists of a 2D display, a micro-lens array (MLA), and a TMD. The TMD comprises square apertures with mirror-reflective inner wall.

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Background: Germ cell tumors (GCTs) account for 2% of human malignancies but are the most common malignant tumors among males aged 15-35. Since 1983, an association between mediastinal GCT (MGCT) and hematologic malignancies has been recognized.

Case Summary: We report a case in which malignant histiocytosis was associated with mediastinal GCTs.

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Recent studies have shown that the expression of integrin-linked kinase (ILK) was related to the occurrence, development, and malignant progression of esophageal squamous cell carcinoma (ESCC). However, research on the relationship between ILK and the chemosensitivity of ESCC has to date not been reported. The present study found that ILK was highly expressed in ESCC cell lines, and the overexpression of ILK in ESCC cells reduced the incidence of cell apoptosis and alleviated the cytotoxicity on cells induced by cisplatin (CDDP).

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  • Sepsis is a serious condition resulting from the body's improper response to infection, with TLR-4 playing a crucial role in inflammation and immune cell death.
  • Clinical trials using monoclonal antibodies targeting TLR-4 and immunotherapy focusing on inflammatory cytokines have not been successful in treating sepsis.
  • Recent research suggests that the innate immune system is more important for controlling sepsis progression than the adaptive immune system, leading to a proposed shift in treatment strategies and highlighting the potential role of TREML4 in sepsis management.
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Background: This study aimed to better understand the prognostic effect of multiple genetic markers and identify more subpopulations at ultra high risk of poor outcome in bone marrow (BM) metastatic neuroblastoma (NB).

Methods: We screened the MYCN, 1p36 and 11q23 loss of heterozygosity (LOH) statuses of 154 patients by interphase fluorescence in situ hybridization of BM cells. The clinical characteristics of patients with the three markers and their associations with prognosis were analysed.

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Trace amounts of components in traditional Chinese medicine are considered pharmacological active substances used for treating many serious diseases. However, purifying all the trace substances and making clear their structures are not easy. In this context, high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry based molecular networking was applied to investigate the chemical constituents of the roots of Aconitum kusnezoffii Reichb.

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In this paper, we propose an optofluidic lenticular lens array (OLLA) for a two-dimensional/three-dimensional (2D/3D) switchable display. The OLLA includes a bottom substrate layer with lenticular lens structure, a microfluidic layer with microchannels, and a top substrate layer with inlets as well as outlets. A micro gap is formed between the lenticular lens of the bottom substrate layer and the top substrate layer.

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Lycii Cortex, the dry root bark of Lycium barbarum(Solanaceae), is rich in chemical compositions with unique structures, such as organic acids, lipids, alkaloids, cyclopeptides and other components, and plays an important role in traditional Chinese medicine. It has the effect of cooling blood and removing steam, clearing lung and reducing fire. It is mainly used in the treatment of hot flashes due to Yin deficiency, hectic fever with night sweat, cough, hemoptysis and internal heat and diabetes.

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Background: To analyze the relationship between tumor viability in specimens retrieved at second-look procedures (SLPs) and clinical outcomes in patients with bladder/prostate rhabdomyosarcoma (BP RMS).

Methods: We retrospectively analyzed patients` characteristics, times between diagnoses and SLPs, types of SLPs, the pathological findings, and clinical outcomes between January 2003 and May 2014.

Results: A total of 29 patients underwent at least one SLP before completing chemotherapy, including 24 boys and 5 girls.

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