Publications by authors named "Xiao-jiao Liu"
Article Synopsis
- Extreme heat exposure leads to significant health issues, particularly affecting the gastrointestinal (GI) tract, which lacks comprehensive research regarding its impact.* -
- In a study of 713 heatstroke patients from 83 centers, 18.5% reported GI symptoms, with those experiencing multiple symptoms facing longer ICU stays and higher mortality rates.* -
- Key factors influencing the occurrence of GI symptoms included older age and lower Glasgow Coma Scale (GCS) scores upon ICU admission, highlighting the need to monitor GI health in heatstroke patients.*
Article Synopsis
- Interleukin 35 (IL-35) is an anti-inflammatory factor that may be involved in the autoimmune disease myasthenia gravis (MG), but its specific roles remain unclear.
- A study analyzed IL-35-producing T and B cells in MG patients compared to healthy controls, revealing significantly lower levels in patients, especially those with thymoma or generalized MG.
- The study suggests that lower IL-35 levels are associated with increased disease activity, indicating that IL-35 could be a potential biomarker for evaluating MG severity.
Article Synopsis
- This study investigates the relationship between atherosclerosis, cerebral blood flow, and cognitive decline in patients with subcortical ischemic vascular dementia (SIVD) compared to Alzheimer’s disease (AD) and healthy controls.
- A total of 44 SIVD patients, 30 AD patients, and 30 healthy individuals underwent evaluations of blood flow and arterial health, revealing SIVD patients had significantly lower mean flow velocity (MFV) and higher pulsatility index (PI) compared to AD patients.
- Results indicate that cognitive function, measured by the Mini-Mental State Examination, correlates positively with MFV but negatively with PI and carotid artery conditions, highlighting the connection between
Article Synopsis
- The study investigates IL-27 serum levels and IL-27-producing cell percentages in patients with acetylcholine receptor antibody-positive myasthenia gravis (AChR-MG) compared to healthy controls.
- Results show that AChR-MG patients had significantly higher serum IL-27 levels and elevated frequencies of IL-27-producing cells, with both metrics decreasing after intravenous immunoglobulin treatment.
- The findings suggest IL-27 may be involved in the disease's pathology and indicate that the percentage of IL-27-producing T cells could serve as a potential biomarker for AChR-MG severity.
Article Synopsis
- - Interleukin-27 (IL-27) is a protein that affects T cell function by regulating the forkhead box P3 (FoxP3) expression, which plays a role in myasthenia gravis (MG) where T cell activation is problematic.
- - In a study involving 59 MG patients and 35 healthy controls, researchers found that IL-27 levels were significantly higher in MG patients, and reduced after treatment with immunoglobulin intravenous (IVIG).
- - The findings suggest that IL-27 could be a useful early marker for diagnosing and monitoring MG, and it may also serve as a treatment target by influencing immune signaling.
Transplantation of umbilical cord-derived mesenchymal stem cells (UC-MSCs) for repair of traumatic brain injury has been used in the clinic. Hyperbaric oxygen (HBO) treatment has long been widely used as an adjunctive therapy for treating traumatic brain injury. UC-MSC transplantation combined with HBO treatment is expected to yield better therapeutic effects on traumatic brain injury.
View Article and Find Full Text PDFEthnopharmacological Relevance: Pennogenyl saponins, the characterized components of Rhizoma Paridis, have been reported to have anticancer activity through induction of apoptosis or anti-metastasis in cultured cells or animal models. The aim of the study was to evaluate the anticancer properties of four pennogenyl saponins (PS1-PS4) on a panel of human cancer and normal cell lines, and explore the potential mechanisms underlying the selective anticancer effects of the steroidal saponins in cancer cells.
Materials And Methods: Differences in the anticancer activity of pennogenyl saponins were examined by MTT assay in human cancer cell lines (HepG2 hepatocellular carcinoma cells, UACC-257 melanoma cells, MCF-7 breast and PC-3 prostate cancer cells) and normal human cell lines (L-02 liver cells and HEK293 kidney cells).
Solitary adrenal metastasis from invasive ductal breast cancer: an uncommon finding.
World J Surg Oncol
January 2010
Background: Invasive ductal carcinoma (IDC) of the breast usually metastasizes to the lungs, liver, bones and brain. Solitary adrenal metastasis is extremely rare. Due to the rarity of this condition, the optimal treatment is unclear.
View Article and Find Full Text PDFObjective: The novel estrogen receptor-alpha (ER-alpha) variant ER-alpha36 is reported to be functional in the estrogen signaling pathway and is related to tamoxifen resistance in breast cancer. However, ER-alpha36 tends to be a favorable factor for survival in patients without tamoxifen therapy. To investigate the mechanisms behind this paradox, we determined the differences between the transcriptional profiles of ER-alpha36 and full-length ER-alpha (ER-alpha66) in breast cancers and matched normal tissues.
View Article and Find Full Text PDFNovel nitro-azobenzene dyes bearing one or two benzophenone branches were proposed and synthesized to improve their photophysical and photochemical properties. The new dyes exhibited double UV/visible bands, and they displayed weak fluorescence emission as excited at 350 nm. Single crystal X-ray diffraction data showed that two phenyl rings of azobenzene was almost coplanar, and the benzophenone part was neither coplanar nor linear connection with azobenzene via ether bridged bond, which have good fit with molecular geometry optimization calculation results.
View Article and Find Full Text PDFObjective: To investigate the clinical application of TRAM-RPAS flap in the one-stage breast reconstruction for patients with breast cancer, and to discuss the method to reduce the incidence of abdominal hernia and abdominal bulging.
Methods: From 2002 to 2004, 16 cases of breast cancer (9 cases in stage I or II and 7 in stage III) received radical resection and breast reconstruction with TRAM-RPAS flaps at the same stage.
Results: Good symmetry was achieved in 12 cases.
[Stereotactic core needle biopsy for diagnosis of mammographic minimal lesions].
Zhejiang Da Xue Xue Bao Yi Xue Ban
September 2006
Objective: To assess the value of X-ray stereotactic core needle biopsy (SCNB) in diagnosis of mammographic minimal lesions.
Methods: Thirty-one cases with suspicious malignant lesions detected by mammography underwent breast biopsy using computer-assisted stereotactic system with spring-loaded biopsy guns and 16G core needles. All specimens underwent histopathologic examination.
[Deep inferior epigastric perforator (DIEP) free flap in immediate breast reconstruction].
Zhonghua Zheng Xing Wai Ke Za Zhi
January 2004
Objective: In order to facilitate psychological rehabilitation of the women who underwent modified radical mastectomy for breast cancer, the DIEP free flap was used for immediate breast reconstruction in a series of patients. We present a review of the surgical outcomes.
Methods: From December 2001 to January 2003, unilateral breast reconstruction was performed in 12 patients using the DIEP free flap at the same time of modified radical mastectomy in our department.