Brain magnetic resonance-imaging findings of anti-N-methyl-D-aspartate receptor encephalitis: a cohort follow-up study in Chinese patients.

The aim of this report was to assess routine clinical brain magnetic resonance imaging (MRI) and its relation to clinical characteristics and disease prognosis. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis patients were consecutively recruited from West China Hospital between October 1, 2011 and April 1, 2016. Brain MRI findings of 106 patients were analysed, and outcomes were assessed at 4, 8, and 12 months after discharge from the hospital using the modified Rankin scale (mRS).

[Distribution patterns of Juglans cathayensis populations at different slope aspects in Tianshan valley in Xinjiang, China].

Eight 4000 m plots were set up at eight sites distributed on sunny and shady slopes of four valleys, and adjacent lattice method was used to survey Juglans cathayensis populations. At different scales, aggregation intensity index such as variance/mean ration and deviation index (C), negative binomial parameter (K), clumping index (I), mean crowding index (m), patchiness index (PAI) and aggregation index (C) were used to analyze distribution patterns of populations. With the increase of surveying scales, the distribution patterns changed from cluster to random.

[Effect of levetiracetam on the sodium currents of rat hippocampal neurons exposed to coriaria lactone].

Objective: To test the effect of Levetiracetam (LEV) on the sodium currents of rat hippocampal neurons exposed to epileptogenic coriaria lactone (CL).

Methods: Acutely isolated Sprague-Dawley Rat hippocampal neurons were subjected to the whole-cell mode of patch clamp under experimental conditions designed to detect voltage-gated sodium currents. The CL (0.

[Effects of coriaria lactone on the sodium currents of actuely isolated rat hippocampal neurons].

Objective: The present study tried to find out the effects of coriaria lactone (CL) on the sodium currents of the rat hippocampal neurons and their significance.

Methods: The sodium currents of the acutely isolated Sprague-Dawley rat hippocampal neurons were recorded by employing the patch-clamp technique in the whole-cell voltage-clamp mode. The effects of CL on the peak currents in the neuron membrane were assessed and analyzed.

[Association analysis of the parkin gene in patients with sporadic Parkinson's disease from a Han population of Sichuan province].

Objective: To determine whether there are any associations between the -258T/G polymorphism of the promoter and the IVS3 -20T/C polymorphism in parkin gene and Parkinson's disease (PD) from a Han population in Sichuan province.

Methods: Polymerase chain reaction (PCR), restriction fragment length polymorphism, denaturing high performance liquid chromatography(dHPLC) and sequence analysis were used to determine the genotype of each subject. The -258T/G polymorphism and IVS3 -20T/C polymorphism were analysed in 198 patients with sporadic PD and 187 healthy controls, matched for age and gender.

[Effect of batroxobin on K+ channel activated by Ca2+ in primary culture rat cortex neurons of rat].

Objective: To investigate the effect of batroxobin on K+ channel activated by Ca2+ in primary cultured cortex neurons of fetal SD rat.

Methods: The patch clamp technique of single channel recordings including cell-attach and inside-out mode was used.

Results: Extracellular batroxobin activated the Kca.

[Effect of the Ca2+ -activated K+ channel in veratridine-induced cortex neurons damage].

Aim: To observe the effects of Ca2+ -activated K+ channel of primary cultured fetal SD rat cortex neurons in the veratridine triggered neuronal damage.

Methods: The patch clamp technique of cell-attach and inside-out mode for these two kinds of single channel recordings were used.

Results: Extracellular veratridine activated the Kca.

[Effect of coriaria lactone on the activation of Ca(2+)-activated K+ channel in hippocampal pyrimidal neurons of rats].

Objective: This research sought to disclose the regulatory effect of Coriaria lactone (CL) on the Ca(2+)-activated K+ channel in hippocampal pyrimidal neurons of Wistar rats in epileptogenesis.

Methods: Cell-attached and inside-out methods of patch clamp technique were used to record the activity of single channel. The sample data were stored in a computer and analyzed by the application of Pclamp softwares.