Publications by authors named "Xiao-hai Liu"

Article Synopsis
  • The common tendinous ring (CTR) is a key anatomical structure at the intersection of important areas in the skull that is vital for neurosurgery and eye-related surgeries.
  • The study involved dissecting skull specimens to understand the 3D structure and relationships of the CTR with surrounding tendons and canals.
  • Findings highlight the CTR's unique dual-ring configuration and emphasize the need for careful surgical techniques to safely navigate this complex area.
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The main purpose of this study was to reveal the nutritional value and antioxidant activity of 34 edible flowers that grew in Yunnan Province, China, through a comprehensive assessment of their nutritional composition and antioxidant indices. The results showed that sample A3 of Asteraceae flowers had the highest total flavonoid content, with a value of 8.53%, and the maximum contents of vitamin C and reducing sugars were from Rosaceae sample R1 and Gentianaceae sample G3, with values of 143.

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Sellar malignant tumors are uncommon and usually reported as metastatic diseases from breast or lung cancers. Spindle cell carcinoma (SCC) is a rare malignancy and has been found in breast,oral cavity,lungs,kidneys,and hepatobiliary pancreatic system but not in sellar region. We report here the first case of isolated sellar SCC with aggressive features in Peking Union Medical College Hospital.

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Article Synopsis
  • The study aimed to investigate how iodine disinfection affects the presence of nasal bacteria in patients undergoing transsphenoidal surgery for pituitary adenomas.
  • Out of 133 patients, nasal bacterial colonization was significantly reduced from 33.8% before disinfection to just 4.5% after iodine treatment, demonstrating an 86.7% elimination rate of the bacteria.
  • The most common bacteria identified were Staphylococcus aureus and Klebsiella pneumoniae, although occurrences of infections post-surgery linked to nasal bacteria were low, with only one patient experiencing mild symptoms that resolved quickly.
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Objective: To investigate the correlation between signal transducer and activator of transcription 3 (STAT3) expression and pituitary adenoma subtypes.

Method: The STAT3 expression profiles in different pituitary adenomas from 74 patients were determined using quantificational real-time polymerase chain reaction,Western blot,and immunohistochemistry.

Results: Expression of STAT3 was observed in all pituitary adenoma subtypes.

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The early diagnosis and treatment of pituitary carcinoma is difficult. The diagnosis is often delayed, and the confirmation of a diagnosis requires the presence of distant subarachnoid,brain or systemic metastasis from the primary pituitary tumor in the sella and also needs the evidences of pathology and imaging of the primary pituitary carcinoma and metastases. Treatment of pituitary carcinoma includes surgery, radiation therapy ,hormone therapy, chemotherapy, and molecularly targeted therapy; however, these methods are mainly palliative and can not prolong the survival.

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Objective: To study the effectiveness of treating giant pituitary adenomas invading cavernous sinus with neuroendoscopy assisted by multiple techniques.

Methods: A total of 72 patients who underwent neuroendoscopic surgery and 55 patients who underwent microscopic surgery for giant pituitary adenomas were enrolled in this retrospective analysis. Both groups received expanded endoscopic endonasal transsphenoidal approach, intraoperative application of navigation, and Doppler.

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Objective: Pituitary tumor transforming gene (PTTG) is an important paracrine growth factor involved in early lactotrope transformation and early onset of angiogenesis in pituitary hyperplasia. Emerging evidences have shown that PTTG expression may contribute to the etiology of pituitary adenomas; but individually published studies showed inconclusive results. This meta-analysis aimed to derive a more precise estimation of the correlations of PTTG expression with human pituitary adenomas.

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Objective: To explore the significance of pseudocapsule in the excision of pituitary adenomas in transsphenoidal surgery.

Methods: For 22 patients with pituitary adenomas over a period of 2 years at Peking Union Medical College Hospital, resection of pseudocapsule was applied for complete tumor removal. Pituitary function test and radiological imaging were performed at pre-operation, 3 months post-operation and at subsequent 6-12 months intervals postoperatively.

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Objective: The aryl hydrocarbon receptor interacting protein gene (AIP) is associated with pituitary adenoma (PA). AIP has not been sequenced in East Asian PA populations, so we performed this study in a Han Chinese cohort.

Design: Our study included six familial PA pedigrees comprising 16 patients and 27 unaffected relatives, as well as 216 sporadic PA (SPA) patients and 100 unrelated healthy controls.

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Familial isolated pituitary adenoma (FIPA) is an autosomal dominant disease, characterized by low penetrance, early-onset disease, more invasive tumor growth, as well as somatotroph and lactotroph adenomas in most cases. It has been indicated that the aryl hydrocarbon receptor interacting protein (AIP) gene is a tumor suppressor gene. Many heterozygous mutations have been discovered in AIP in about 20% of FIPA families.

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Clinically nonfunctioning pituitary adenomas are the most common types among pituitary adenomas. These tumors are usually diagnosed in their later stages due to the absence of clinical symptoms and detectable hormonal hypersecretion. Although these tumors are benign, they are hard to be completely removed during neurosurgery due to the massive invasion into the surrounding tissues at diagnosis.

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The BES-III Collaboration recently reported the observation of anomalously large isospin violations in J/ψ→γη(1405/1475)→γπ(0)f(0)(980)→γ+3π, where the f(0)(980) in the ππ invariant mass spectrum appears to be much narrower (~10 MeV) than the peak width (~50 MeV) measured in other processes. We show that a mechanism, named as triangle singularity (TS), can produce a narrow enhancement between the charged and neutral KK¯ thresholds, i.e.

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To investigate influences of mining activities on heavy metal contamination and health risk in vegetable of mining-affected area, the present study was undertaken as a preliminary survey of As, Cd, Co, Cr, Cu, Ni, Pb and Zn concentrations of majority vegetables and soils in area affected by an ancient tin ore, Yunnan province. Based on the soil heavy metals investigated, average Nemero index of soil heavy metals reach 50.1, showed that vegetable fields were contaminated by heavy metals, especially As: average As concentration of soils could reach 1225 mg x kg(-1).

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