Publications by authors named "Xiao-gang Sheng"
Objective: To evaluate the efficacy and safety of a combination therapy using Chinese medicine (CM) Shenzhu Guanxin Recipe (, SGR) and standard Western medicine treatment (SWMT) in patients with angina pectoris after percutaneous coronary intervention (PCI).
Methods: Double-blind randomized controlled trial was used in this experimental procedure. One hundred and eighty-seven patients with coronary heart disease receiving SWMT after PCI were randomly assigned to the treatment (SGR) and control (placebo) groups.
Article Synopsis
- Percutaneous coronary intervention (PCI) is commonly used for treating coronary artery disease, but its effectiveness in reducing restenosis and improving quality of life has been limited.
- A clinical trial assessed the impact of the Huxin Formula, a modified Chinese medicine, on patients undergoing PCI, revealing no significant differences in primary outcomes between the treatment and control groups.
- However, patients with good ejection fractions and those with unstable angina reported better quality of life scores after using the Huxin Formula, with no serious side effects observed, suggesting it may be a safe option for certain patients post-PCI.
[Effect of clinical pathways based on integrative medicine for patients with chronic heart failure: a multi-center research].
Zhongguo Zhong Xi Yi Jie He Za Zhi
June 2013
Objective: To assess a multi-center study effectiveness of clinical pathways based on integrative medicine (IM) for chronic heart failure (CHF) patients.
Methods: A combined method of historical control study and clinical study on concurrent control was used. After the standard management for clinical pathways was carried out in four hospitals at home, the effects on hospitalization days, medical expenses, clinical efficacy, patient satisfaction, and quality of life were assessed.
[Clinical epidemiologic investigation on Chinese medicine syndrome laws in patients with chronic heart failure].
Zhongguo Zhong Xi Yi Jie He Za Zhi
July 2011
Objective: To study the distribution laws of Chinese medicine syndromes in patients with chronic heart failure (CHF) by clinical epidemiologic investigation.
Methods: 512 CHF patients were studied, including 168 items of symptoms and 48 items of tongue and pulse pictures. A database of Chinese medicine syndromes was established, and 9 disease nature elements and 5 disease location elements were extracted.
[Double blinded randomized and controlled study on treatment of chronic heart failure by nuanxin capsule].
Zhongguo Zhong Xi Yi Jie He Za Zhi
January 2011
Objective: To evaluate the effect and safety of Nuanxin Capsule (NXC) in treating patients with chronic heart failure (CHF).
Methods: Adopting the randomized, positive controlled, double-blinded design, 150 CHF patients were assigned to the treatment group and the control group equally, they were treated with optimal western medical therapeutic scheme in combining respectively with NXC and placebo for 24 weeks. The indices for effectiveness and safety evaluation, such as Chinese medicine syndrome, grade of heart function, myocardial contraction, as well as the re-hospitalization rate and mortality, were observed.
Objective: To induce the differentiation of rabbit bone marrow mesenchymal stem cells (MSCs) into myogenic cells in vitro, and to investigate the expression of vascular endothelial growth factor (VEGF) gene in AdTrackCMV-hVEGF165- transfected MSCs.
Methods: Twenty rabbits were divided equally into control group and experimental group, and MSCs were isolated and purified from their bone marrow by Percoll (1.073 g/ml) followed by cell culture in low-glucose DMEM supplemented with 10% fetal bovine serum.