Publications by authors named "Xiao-dong Pang"
Background: In recent years, the mechanical concept of intervertebral disc regeneration has become more and more popular due to the increasing awareness of the importance of preservation of spine movement. Interestingly, there is increasing evidence, however, that dynamic stabilization systems may compensate non-physiological loads, limit pathological movement, normalize disc height and intradiscal pressure, and provide an adaptive environment for disc regeneration.
Case Summary: The patient was a 54-year-old man, who presented with a 10-year history of mechanical back pain, which had become progressively serious and radiated into the left lower limb with numbness 3 mo prior.
Objective: To report a group of special patients showing a normal signal intensity of MRI with a positive discography and discuss its pathogenesis and clinical significance.
Methods: From August 2003 to November 2008, 288 patients with chronic low back pain were treated. Of these patients, 12 showed a normal intensity signal of MRI in lumbar intervertebral discs with a positive discography.
Article Synopsis
- The study aimed to understand the natural progression and treatment outcomes for patients with discogenic low back pain, to enhance clinical guidance for managing the condition.
- A total of 72 patients were hospitalized and divided into two groups: one received an intradiscal injection of methylene blue and the other a placebo, with follow-up assessments conducted over four years.
- Results showed that most patients experienced little to no improvement in their symptoms over time, indicating that discogenic low back pain tends to be a chronic and unchanging condition.
Objective: To evaluate the ability of a polycaprolactone/polylactic acid (PCL/PLA) membrane to inhibit epidural scar adhesion after laminectomy, and observe the responsive changes of the pain media in the spinal cord.
Methods: L(1), L(3) laminectomies were performed on 96 Wistar rats. The rats were divided into 3 groups: None-implant Control Group (NC), Autologous free fat graft group (AFFG) and PCL/PLA membrane group (PCL/PLAm).