Cadophorin C, a new cyclic heptapeptide isolated from a mangrove-derived fungus sp. GXIMD 03101.

One new cyclic heptapeptide, cadophorin C (), and one known analogue cadophorin B () were isolated from the mangrove-derived fungus sp. GXIMD 03101 from the mangrove  L. The chemical structure of was elucidated by comprehensive analysis of the spectroscopic data, including 1D and 2D NMR and HRESIMS, and the known compound was identified by comparing the data with literature values.

Molecular and genetic regulation of petal number variation.

Floral forms with an increased number of petals, also known as double-flower phenotypes, have been selected and conserved in many domesticated plants, particularly in ornamentals, because of their great economic value. The molecular and genetic mechanisms that control this trait are therefore of great interest, not only for scientists, but also for breeders. In this review, we summarize current knowledge of the gene regulatory networks of flower initiation and development and known mutations that lead to variation of petal number in many species.

Genomes of Meniocus linifolius and Tetracme quadricornis reveal the ancestral karyotype and genomic features of core Brassicaceae.

Brassicaceae represents an important plant family from both a scientific and economic perspective. However, genomic features related to the early diversification of this family have not been fully characterized, especially upon the uplift of the Tibetan Plateau, which was followed by increasing aridity in the Asian interior, intensifying monsoons in Eastern Asia, and significantly fluctuating daily temperatures. Here, we reveal the genomic architecture that accompanied early Brassicaceae diversification by analyzing two high-quality chromosome-level genomes for Meniocus linifolius (Arabodae; clade D) and Tetracme quadricornis (Hesperodae; clade E), together with genomes representing all major Brassicaceae clades and the basal Aethionemeae.

Hippocampal volume and resting-state functional connectivity on magnetic resonance imaging in patients with Parkinson and depression.

Background: Recent structural and functional imaging studies of depression in Parkinson disease (DPD) have failed to reveal the relevant mechanism, and relatively few studies have been conducted on limbic systems such as the hippocampus. This study thus aimed to gain new insights into the pathogenesis of DPD by detecting the changes in the hippocampal structure and the resting-state functional connectivity (FC) of patients with DPD.

Methods: This study included 30 patients with DPD (DPD group), 30 patients with nondepressed Parkinson disease (NDPD; NDPD group), and 30 normal controls (NCs; NC group) with no significant age or gender differences with the DPD group.

A comparative full-length transcriptomic resource provides insight into the perennial monocarpic mass flowering.

Perennial monocarpic mass flowering represents as a key developmental innovation in flowering time diversity in several biological and economical essential families, such as the woody bamboos and the shrubby Strobilanthes. However, molecular and genetic mechanisms underlying this important biodiversity remain poorly investigated. Here, we generated a full-length transcriptome resource incorporated into the BlueOmics database (http://blueomics.

Association between napping and 24-hour blood pressure variability among university students: A pilot study.

Background: Blood pressure variability (BPV) has been reported to be a predictor of cardiovascular and some cognitive diseases. However, the association between napping and BPV remains unknown. This study aimed to explore the association between napping and BPV.

Arabidopsis AGAMOUS-LIKE16 and SUPPRESSOR OF CONSTANS1 regulate the genome-wide expression and flowering time.

Flowering transition is tightly coordinated by complex gene regulatory networks, in which AGAMOUS-LIKE 16 (AGL16) plays important roles. Here, we identified the molecular function and binding properties of AGL16 and demonstrated its partial dependency on the SUPPRESSOR OF CONSTANS 1 (SOC1) function in regulating flowering. AGL16 bound to promoters of more than 2,000 genes via CArG-box motifs with high similarity to that of SOC1 in Arabidopsis (Arabidopsis thaliana).

Application of the maximum threshold distances to reduce gene flow frequency in the coexistence between genetically modified (GM) and non-GM maize.

On the coexistence of genetically modified (GM) and non-GM maize, the isolation distance plays an important role in controlling the transgenic flow. In this study, maize gene flow model was used to quantify the MTD and MTD in the main maize-planting regions of China; those were the maximum threshold distance for the gene flow frequency equal to or lower than 1% and 0.1%.

Complex and reticulate origin of edible roses (Rosa, Rosaceae) in China.

While roses are today among the most popular ornamental plants, the petals and fruits of some cultivars have flavored foods for millennia. The genetic origins of these edible cultivars remain poorly investigated. We collected the major varieties of edible roses available in China, assembled their plastome sequences, and phased the haplotypes for internal transcribed spacers (ITS1/ITS2) of the 18S-5.

Rose without prickle: genomic insights linked to moisture adaptation.

Prickles act against herbivores, pathogens or mechanical injury, while also preventing water loss. However, whether prickles have new function and the molecular genetics of prickle patterning remain poorly explored. Here, we generated a high-quality reference genome assembly for 'Basye's Thornless' (BT), a prickle-free cultivar of , to identify genetic elements related to stem prickle development.

Expansion and expression diversity of genes provides insights into flowering time regulation in roses.

Roses are important horticultural plants with enormous diversity in flowers and flowering behavior. However, molecular regulation of flowering time variation in roses remains poorly characterized. Here, we report an expansion of the genes that correlates well with the switch to prostrate-to-erect growth of shoots upon flowering in 'Basye's Thornless' (BT).

Comparison on nutritional quality of adult female Chinese mitten crab (Eriocheir sinensis) with different colored hepatopancreases.

White hepatopancreas syndrome has recently emerged in Chinese mitten crab (Eriocheir sinensis) aquaculture, causing considerable economic loss. The hepatopancreas color of diseased crabs becomes gradually lighter, turning from yellow to yellow-white to white. Therefore, this study was conducted to investigate the changes in nutrient composition in three edible parts (hepatopancreas, ovaries, and muscle) of adult females with different colored hepatopancreases.

The complete chloroplast genome sequence of a rambler rose, (Rosaceae).

The rambler Crép. is an important founder species during modern rose domestication. However, the chloroplast genome (plastome) of this wild species remains unavailable.

Genome-wide identification of WD40 genes reveals a functional diversification of COP1-like genes in Rosaceae.

Genome-wide identification of WD40-like genes reveals a duplication of COP1-like genes, one of the key players involved in regulation of flowering time and photomorphogenesis, with strong functional diversification in Rosaceae. WD40 proteins play crucial roles in a broad spectrum of developmental and physiological processes. Here, we conducted a systematic characterization of this family of genes in Rosa chinensis 'Old Blush' (OB), a founder genotype for modern rose domestication.

[Toxicity of PM Based on a Battery of Bioassays].

To accurately evaluate the biotoxicity of PM, PM samples from winter fog-haze days, winter normal days, and summer days in Changzhou were selected for evaluation based on the acute toxicity of luminescent bacteria and zebrafish embryos and the cytotoxicity of human lung adenocarcinoma cells in vitro (A549). The three atmospheric conditions and the physical and chemical indicators were also evaluated using correlation analysis. The PM samples showed either acute or developmental toxicity during all three periods.

Apatinib Combined with Local Irradiation Leads to Systemic Tumor Control via Reversal of Immunosuppressive Tumor Microenvironment in Lung Cancer.

Purpose: This study aimed to investigate the potential systemic antitumor effects of stereotactic ablative radiotherapy (SABR) and apatinib (a novel vascular endothelial growth factor receptor 2 inhibitor) via reversing the immunosuppressive tumor microenvironment for lung carcinoma.

Materials And Methods: Lewis lung cancer cells were injected into C57BL/6 mice in the left hindlimb (primary tumor; irradiated) and in the right flank (secondary tumor; nonirradiated). When both tumors grew to the touchable size, mice were randomly divided into eight treatment groups.

[Stability characteristics of soil organic carbon pool following development of sand-fixing forest in Mu Us sandy land, China].

The study aimed to reveal the cumulative effects and stability characteristics of soil organic carbon (SOC) during forest development at the Mu Us sandy land, China. Using space for time substitution, surface soil samples were collected from semi-fixed sandy lands and restored arbor and shrub lands with the ages of 22, 32 and 53 years in the Yulin sand control region in Northern Shaanxi Province. The content of total organic carbon (TOC), oxidizable labile organic carbon, and resistant carbon and the characteristics of mineralized carbon emission and decomposition ratio were analyzed.

Periodic surface structures on dielectrics upon femtosecond laser pulses irradiation.

The formation of laser-induced periodic surface structures (LIPSS) on two different dielectrics of K9 glass and fused silica upon irradiation in ambient conditions and in vacuum with multiple femtosecond (fs) laser pulse sequences at different pulse durations (35 fs, 260 fs, and 500 fs) was studied experimentally. Three types of LIPSS, so-called high-spatial-frequency LIPSS (HSFL), low-spatial-frequency LIPSS (LSFL), and supra-wavelength periodic surface structures (SWPSS) with different spatial periods and orientations were identified. The appearance was characterized with respect to the experimental parameters of laser fluence and number of laser pulses per spot.

[Distribution Characteristics of Antibiotic Resistance Genes in PM of a Concentrated Broiler Feeding Operation].

Concentrated poultry feeding operations are an important source of antibiotic resistance genes (ARGs). Little attention has been given to PM as a mechanism for exposing ARGs to humans. In this study, PM and fecal samples from inside the broiler feeding operation and PM samples from outside the broiler feeding operation were collected.

Reevaluation of the post-marketing safety of Xuebijing injection based on real-world and evidence-based evaluations.

Aims: To determine the causes of adverse reactions associated with Xuebijing injection and provide medical evidence for its safe and rational post-marketing use in clinical practice.

Materials And Methods: We used prospective nested case-control and prescription sequence analysis designs. Using data from the Hospital Information System, patients exhibiting trigger signals after receiving Xuebijing injection were classified as suspected allergic patients.

Apatinib combined with docetaxel as a salvage treatment for metastatic esophageal squamous cancer: a case report.

The first-line treatment for metastatic esophageal squamous cell cancer (ESCC) is a platinum- or fluorouracil-based agent, followed by later treatment with taxanes or irinotecan. However, there is still no standard third-line treatment for patients with metastatic ESCC. We present a 62-year-old man initially diagnosed with locally advanced ESCC.

[Community Structure and Influencing Factors of Bacterioplankton in Spring in Zhushan Bay, Lake Taihu].

In order to investigate the characteristics of bacterioplankton in the spring in Zhushan Bay, Lake Taihu, the 16S rRNA gene of the bacterioplankton at four sampling sites in Zhushan Bay was sequenced by high-throughput sequencing using water samples collected from Yapugang, Shatanggang, Zhushanhunan, and Jiaoshan. The results showed that the coverage of the sequencing library was very high and could accurately represent the bacterioplankton community in the samples. The species richness of Jiaoshan was the highest, but the species evenness was lower.