Zhonghua Fu Chan Ke Za Zhi
July 2003
Objective: To demonstrate the histomorphometric changes of postmenopausal osteoporosis (PMO) goat model after bilateral ovariectomy (OVX).
Methods: Fifteen female goats were randomly enrolled into four groups: 3 goats without any treatment (group C), 3 goats sham-operated only (group S), 4 goats 6 months after OVX (group OVX6M), 5 goats 18 months after OVX (group OVX18M). On the 21st and 9th day prior to sacrifice, tetracycline was given to them in order to label the bone for dynamic study.