Euthyroid sick syndrome and nutritional status are correlated with hyposelenemia in hemodialysis patients.

Background: Maintenance hemodialysis (HD) patients have altered levels of thyroid hormone (TH) in euthyroid sick syndrome, along with low T3 levels and several nutritional metabolic disturbances. Selenium (Se) is an essential trace element for living organisms, which has been shown to play a major role in thyroid hormone levels and the nutritional metabolism. The aims of the present study were to assess the changes in serum levels of selenium and their correlation with disorders of the endocrine and nutritional metabolism in HD patients.

[Proliferation of the mesenchymal stem cells in a delayed fat flap: an experimental study in rabbits].

Objective: To investigate the possibility to enhance the proliferation of adipose-derived stem cells (ASCs) in a delayed fat flap in rabbits.

Methods: A delayed fat flap was formed in one side of inguinal region of a rabbit. 21 days after operation, the fat tissues at the delayed flaps and at the unoperated side were harvested and digested with 0.

Th1 polarization and low-T3 syndrome are correlated with hyperleptinemia in hemodialysis patients.

Background: Patients undergoing chronic hemodialysis (HD) have an impaired immune response with a dysregulated Th1/Th2 cytokine network and altered the levels of thyroid hormone (TH) in euthyroid sick syndrome. Leptin, an adipocyte-secreted hormone, is considered to be a proinflammatory adipocytokine, with multiple effects on several tissues acting on the intermediate and energy metabolism. The aims of the present study were to assess the changes in serum levels of leptin and their correlation with Th1/Th2 cytokine and TH production in HD patients.

[Experimental study of increasing effect of the fat flap tissue after delay operation on its free graft survival volume and duration].

Objective: To observe the effects of the fat flap tissues after delay operation on free fat-graft survival rate and duration.

Methods: The delay operation of fat flaps was performed in the inguinal region of a rabbit. Expression of VEGF was assayed using Elisa method after 12 hours of flap delay.

[Effect of lanthanum chloride on expressions of collagen protein in a wound tissue].

Objective: To evaluate the effect of lanthanum chloride on expressions of collagen protein and find a way to prevent and treat scar.

Methods: Four linear incisions were made on the dorsal skin of an adult, female Sprague-Dawley rat as an animal model. One was non-manipulated as a control; the second was injected with distilled water as a sham-control; the third was injected with 50 mmol/L of lanthanum chloride, and the fourth was injected with 50 micrograms neutralizing antibody of TGF-beta 1 as a positive control.

[Effects of lanthanum chloride on the apoptosis of fibroblasts in trauma tissue].

Objective: To investigate the effects of lanthanum chloride on the apoptosis of fibroblasts in trauma tissue.

Methods: Fifty adult female SD rats were used and linear incisions were made on the back near the joints of extremities of the rats. One of the cuts receiving no treatment was designated as blank control (C).