A Case of NTRK Fusion Corpus Sarcoma With Pseudobiphasic Growth Pattern and Literature Review.

The incidence of neurotrophic tyrosine kinase receptor (NTRK) fusion uterine sarcoma is extremely low, and reports have been mostly focused on cases localized to the cervix. So far, only 4 cases have been reported of the uterine corpus. In this study, we reported a case of NTRK fusion corpus sarcoma.

A colorimetric sensing strategy based on chitosan-stabilized platinum nanoparticles for quick detection of α-glucosidase activity and inhibitor screening.

α-Glucosidase (α-Glu) is implicated in the progression and pathogenesis of type II diabetes (T2D). In this study, we developed a rapid colorimetric technique using platinum nanoparticles stabilized by chitosan (Ch-PtNPs) to detect α-Glu activity and its inhibitor. The Ch-PtNPs facilitate the conversion of 3,3',5,5'-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB) in the presence of dissolved O.

Multiplex modification of Yarrowia lipolytica for enhanced erythritol biosynthesis from glycerol through modularized metabolic engineering.

Erythritol is a novelty 4-carbon sugar polyol and has great potential to be used as the precursor of some platform chemicals. The increasing cost of glucose poses researchers shifting insights to the cheaper biodiesel raw materials. Herein, we engineered a non-degradation, non-byproducts Yarrowia lipolytica for the erythritol production with high-titer from glycerol.

Harmonics of Parton Saturation in Lepton-Jet Correlations at the Electron-Ion Collider.

Parton saturation is one of the most intriguing phenomena in the high energy nuclear physics research frontier, especially in the upcoming era of the Electron-Ion Collider (EIC). The lepton-jet correlation in deep inelastic scattering provides us with a new gateway to the parton saturation at the EIC. In particular, we demonstrate that azimuthal angle anisotropies of the lepton-jet correlation are sensitive to the strength of the saturation momentum in the EIC kinematic region.

Simvastatin Reduces NETosis to Attenuate Severe Asthma by Inhibiting PAD4 Expression.

Objective: Patients with severe asthma respond poorly to corticosteroids, and their care accounts for more than 60% of the total costs attributed to asthma. Neutrophils form neutrophil extracellular traps (NETs), which play a crucial role in severe asthma. Statins have shown anti-inflammatory effects by reducing NETosis.

Pursuing the Precision Study for Color Glass Condensate in Forward Hadron Productions.

With the tremendous accomplishments of RHIC and the LHC experiments and the advent of the future electron-ion collider on the horizon, the quest for compelling evidence of the color glass condensate (CGC) has become one of the most aspiring goals in the high energy quantum chromodynamics research. Pursuing this question requires developing the precision test of the CGC formalism. By systematically implementing the threshold resummation, we significantly improve the stability of the next-to-leading-order calculation in CGC for forward rapidity hadron productions in pp and pA collisions, especially in the high p_{T} region, and obtain reliable descriptions of all existing data measured at RHIC and the LHC across all p_{T} regions.

Elevated expression of the RNA-binding motif protein 43 predicts poor prognosis in esophageal squamous cell carcinoma.

RNA-binding proteins (RBPs) play crucial roles in the post-transcriptional regulation of mRNA during numerous physiological and pathological processes, including tumor genesis and development. However, the role of RNA-binding motif protein 43 (RBM43) in esophageal squamous cell carcinoma (ESCC) has not been reported so far. The current study was the first to evaluate RBM43 protein expression by immunohistochemistry (IHC) in an independent cohort of 207 patients with ESCC, to explore its potential prognostic value and clinical relevance in ESCC.

Anisotropy in Dijet Production in Exclusive and Inclusive Processes.

We investigate the effect of soft gluon radiations on the azimuthal angle correlation between the total and relative momenta of two jets in inclusive and exclusive dijet processes. We show that the final state effect induces a sizable cos(2ϕ) anisotropy due to gluon emissions near the jet cones. The phenomenological consequences of this observation are discussed for various collider experiments, including diffractive processes in ultraperipheral pA and AA collisions, inclusive and diffractive dijet production at the EIC, and inclusive dijet in pp and AA collisions at the LHC.

Momentum Anisotropy of Leptons from Two-Photon Processes in Heavy-Ion Collisions.

We investigate the azimuthal angular correlation between the lepton transverse momentum P_{⊥} and the impact parameter b_{⊥} in noncentral heavy-ion collisions, where the leptons are produced through two-photon scattering. Among the Fourier harmonic coefficients, a significant v_{4} asymmetry is found for the typical kinematics at RHIC and LHC with a mild dependence on the P_{⊥}, whereas v_{2} is power suppressed by the lepton mass over P_{⊥}. This unique prediction, if confirmed from the experiments, shall provide crucial information on the production mechanism for the dilepton in two-photon processes.

Elliptic Flow of Heavy Quarkonia in pA Collisions.

Using the dilute-dense factorization in the color glass condensate framework, we investigate the azimuthal angular correlation between a heavy quarkonium and a charged light hadron in proton-nucleus collisions. We extract the second harmonic v_{2}, commonly known as the elliptic flow, with the light hadron as the reference. This particular azimuthal angular correlation between a heavy meson and a light hadron was first measured at the LHC recently.

Acoplanarity of a Lepton Pair to Probe the Electromagnetic Property of Quark Matter.

We investigate the P_{T}-broadening effects in dilepton production through photon-photon scattering in heavy ion collisions. The QED multiple interaction effect with the medium is found to be consistent with the recent observation of a low transverse momentum lepton pair from the ATLAS Collaboration at the LHC. We further comment on the magnetic broadening effect and point out a number of ways to disentangle these two mechanisms.

Co-metal-organic-frameworks with pure uniform crystal morphology prepared via Co exchange-mediated transformation from Zn-metallogels for luminol catalysed chemiluminescence.

Cation exchange-mediated transformation from Zn-metallogels (MOGs), which was a mild facile strategy relative to the demanding hydrothermal method, was employed to develop Co metal-organic frameworks (Co-MOFs) at room temperature. The obtained Co-MOFs was of uniform octahedral morphology and possessed high activity to catalyze luminol chemiluminescence without extra oxidants. By adding cysteine, the CL emission of luminol-Co-MOFs system was further enhanced.

Tumor necrosis factor receptor-associated factor 6 (TRAF6) participates in anti-lipopolysaccharide factors (ALFs) gene expression in mud crab.

Tumor necrosis factor receptor-associated factor 6 (TRAF6) is a key cytoplasm signal adaptor that mediates signals activated by tumor necrosis factor receptor (TNFR) superfamily and the Interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily. The full-length 2492 bp TRAF6 (Sp-TRAF6) from Scylla paramamosain contains 1800 bp of open reading frame (ORF) encoding 598 amino acids, including an N-terminal RING-type zinc finger, two TRAF-type zinc fingers and a conserved C-terminal meprin and TRAF homology (MATH) domain. Multiple alignment analysis shows that the putative amino acid sequence of Sp-TRAf6 has highest identity of 88% with Pt-TRAF6 from Portunus trituberculatus, while the similarity of Sp-TRAF6 with other crustacean sequences was 54-55%.

Probing the Small-x Gluon Tomography in Correlated Hard Diffractive Dijet Production in Deep Inelastic Scattering.

We investigate the close connection between the quantum phase space Wigner distribution of small-x gluons and the color dipole scattering amplitude, and we propose studying it experimentally in the hard diffractive dijet production at the planned electron-ion collider. The angular correlation between the nucleon recoiled momentum and the dijet transverse momentum probes the nontrivial correlation in the phase space Wigner distribution. This experimental study not only provides us with three-dimensional tomographic pictures of gluons inside high energy protons-it gives a unique and interesting signal for the small-x dynamics with QCD evolution effects.

[Immunoreactivity and immunogenicity analysis of the recombinant cathepsin L-like protease of Fasciola hepatica in SD rats].

Objective: To analyze the immunoreactivity of recombinant cathepsin L-like proteases (CatL) protein of Fasciola hepatica and its immunogenicity in SD rats.

Methods: The E. coli BL21(DE3) cells harbouring recombinant plasmid pET30a-FhCatL were inoculated in LB medium, and the protein expression was induced with IPTG.

Enhancement of the immune response and protection against Vibrio parahaemolyticus by indigenous probiotic Bacillus strains in mud crab (Scylla paramamosain).

In a previous study, bacterial communities of the intestine in three populations of crabs (wild crabs, pond-raised healthy crabs and diseased crabs) were probed by culture-independent methods. In this study, we examined the intestinal communities of the crabs by bacterial cultivation with a variety of media. A total of 135 bacterial strains were isolated from three populations of mud crabs.

Towards the test of saturation physics beyond leading logarithm.

We present results from the first next-to-leading-order (NLO) numerical analysis of forward hadron production in pA and dA collisions in the small-x saturation formalism. Using parton distributions and fragmentation functions at NLO, as well as the dipole amplitude from the solution to the Balitsky-Kovchegov equation with running coupling, together with the NLO corrections to the hard coefficients, we obtain a good description of the available RHIC data in dAu collisions. In the large p⊥ region beyond the saturation scale, we find that the NLO correction becomes dominant and negative, which indicates that other physics beyond NLO becomes important and should also be taken into account.

Sudakov resummation in the small-x saturation formalism.

Through an explicit calculation of massive scalar particle (e.g., Higgs boson) production in high energy pA collisions up to one-loop order, we demonstrate, for the first time, that the Sudakov-type logarithms in hard processes in the small-x saturation formalism can be systematically separated from the small-x logarithms.

[Immunogenicity analysis of recombinant GST protein of Fasciola hepatica in SD rats].

Objective: To analyze the immunogenicity of recombinant glutathione S-transferase protein of Fasciola hepatica (FhGST) in SD rats.

Methods: The recombinant expression plasmid pET30a-FhGST was transformed into E. coli BL21 (DE3) cells and induced with IPTG for protein expression.

One-loop factorization for inclusive hadron production in p-A collisions in the saturation formalism.

We demonstrate the QCD factorization for inclusive hadron production in p-A collisions in the saturation formalism at one-loop order, with explicit calculation of both real and virtual gluon radiation diagrams. In particular, we find that the cross section can be written into a factorization form in the coordinate space at the next-to-leading order, while the naive form of the convolution in the transverse momentum space does not hold. The collinear divergences associated with the incoming parton distribution of the nucleon and the outgoing fragmentation function of the final-state hadron, as well as the rapidity divergence with small-x dipole gluon distribution of the nucleus are factorized into the splittings of the associated parton distribution and fragmentation functions and the energy evolution of the dipole gluon distribution function.

QCD resummation for single spin asymmetries.

We study the transverse momentum dependent factorization for single spin asymmetries in Drell-Yan and semi-inclusive deep inelastic scattering processes at one-loop order. The next-to-leading order hard factors are calculated in the Ji-Ma-Yuan factorization scheme. We further derive the QCD resummation formalisms for these observables following the Collins-Soper-Sterman method.

k(t) factorization for hard processes in nuclei.

Two widely proposed k(t)-dependent gluon distributions in the small-x saturation regime are investigated using two-particle back-to-back correlations in high energy scattering processes. The Weizsäcker-Williams gluon distribution, interpreted as the number density of gluon inside nucleus, is studied in the quark-antiquark jet correlation in deep inelastic scattering. On the other hand, the unintegrated gluon distribution, defined as the Fourier transform of the color-dipole cross section, is probed in the direct photon-jet correlation in pA collisions.

Nonuniversality of transverse momentum dependent parton distributions at small x.

We study the universality issue of the transverse momentum dependent parton distributions at small x, by comparing the initial and final state interaction effects in di-jet-correlations in pA collisions with those in deep inelastic lepton-nucleus scattering. We demonstrate the nonuniversality by performing an explicit calculation in a particular model where the multiple gauge boson exchange contributions are summed up to all orders. We comment on the implications of our results on the theoretical interpretation of dihadron correlation in dA collisions in terms of the saturation phenomena in deep inelastic lepton-nucleus scattering.

[Cloning, expression and immunogenicity analysis of cathepsin L-like protease of Fasciola hepatica].

Objective: To clone and express the cathepsin L-like protease gene of Fasciola hepatica (FhCL) and investigate the immunogenicity of the recombinant FhCL protein.

Methods: Specific primers were designed according to the reported FhCL gene in GenBank. Using total RNA from adult worms of F.

Reproduction response of Chinese mitten-handed crab (Eriocheir sinensis) fed different sources of dietary lipid.

The effect of feeding three semi-purified diets containing different lipid sources (anchovy oil, soybean oil and pork lard) on fecundity, hatchability and egg fatty acid composition of Chinese mitten-handed crab (Eriocheir sinensis) broodstock was compared with a fresh clam diet in a 6-month feeding trial. Broodstock crabs fed the diet containing pork lard showed poor fecundity and low hatchability. Crabs fed the diet containing soybean oil showed improved fecundity; however, no significant improvement in hatchability was observed.