Publications by authors named "Xiao-Yue Shan"
Article Synopsis
- The study focused on assessing the risks of exposure to welding fumes and airborne heavy metals in electronic manufacturing workshops in Hangzhou, China.
- Air samples from welding workshops showed high levels of contaminants like manganese (Mn) and iron (Fe), with Mn strongly correlating with Fe, while non-welding workshops had elevated copper (Cu) levels.
- Health risk assessments indicated that while some metal exposure in welding workshops exceeded permissible limits, the lifetime cancer risks were acceptable, but non-cancer risks for Mn were concerning in both types of workshops.
Association between serum copper/zinc ratio and lung cancer: A systematic review with meta-analysis.
J Trace Elem Med Biol
December 2022
Article Synopsis
- * A total of 39 studies with nearly 4,000 lung cancer patients and over 3,000 healthy controls were analyzed, revealing that lung cancer patients had significantly higher serum copper/zinc ratios compared to healthy individuals and those with benign lung diseases.
- * The findings suggest that an elevated serum copper/zinc ratio may be linked to a higher risk of developing lung cancer, with higher ratios observed in patients at more advanced stages of the disease.
The sensitive detection of heavy metal ions in the organism and aquatic ecosystem using nanosensors based on environment friendly and biocompatible materials still remains a challenge. A fluorescent turn-on nanosensor for lead (II) detection based on biocompatible graphene quantum dots and graphene oxide by employment of Pb(2+)-induced G-quadruplex formation was reported. Graphene quantum dots with high quantum yield, good biocompatibility were prepared and served as the fluorophore of Pb(2+) probe.
View Article and Find Full Text PDFConvenient and simultaneous detection of multiple biomarkers such as DNA and proteins with biocompatible materials and good analytical performance still remains a challenge. Herein, we report the respective and simultaneous detection of DNA and bovine α-thrombin (thrombin) entirely based on biocompatible carbon materials through a specially designed fluorescence on-off-on process. Colorful fluorescence, high emission efficiency, good photostability and excellent compatibility enables graphene quantum dots (GQDs) as the best choice for fluorophores in bioprobes, and thus two-colored GQDs as labeling fluorophores were chemically bonded with specific oligonucleotide sequence and aptamer to prepare two probes targeting the DNA and thrombin, respectively.
View Article and Find Full Text PDFDNA nanosensor based on biocompatible graphene quantum dots and carbon nanotubes.
Biosens Bioelectron
October 2014
An ultrasensitive nanosensor based on fluorescence resonance energy transfer (FRET) between biocompatible graphene quantum dots and carbon nanotubes for DNA detection was reported. We take advantage of good biocompatibility and strong fluorescence of graphene quantum dots, base pairing specificity of DNA and unique fluorescence resonance energy transfer between graphene quantum dots and carbon nanotubes to achieve the analysis of low concentrations of DNA. Graphene quantum dots with high quantum yield up to 0.
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