Publications by authors named "Xiao-Yuan Ji"
Article Synopsis
- This study addresses the limitations of current methods assessing mitochondrial complex activity, which often require fresh and large samples and focus on single reactions within mitochondria.
- Researchers developed a sensitive analytical technique using mass spectrometry to measure a range of metabolites (MRCMs) that reflect overall mitochondrial function at the whole-cell level instead.
- By applying machine learning, they identified specific metabolites related to Complex I activity, providing a new approach to evaluate mitochondrial health without the constraints of traditional methods.
The improved wear and corrosion resistance of gray cast iron (GCI) with enhanced mechanical properties is a proven stepping stone towards the longevity of its versatile industrial applications. In this article, we have tailored the microstructural properties of GCI by alloying it with titanium (Ti) and tungsten (W) additives, which resulted in improved mechanical, wear, and corrosion resistance. The results also show the nucleation of the B-, D-, and E-type graphite flakes with the A-type graphite flake in the alloyed GCI microstructure.
View Article and Find Full Text PDFSelective laser melting (SLM) of high-temperature alloys involves intricate interdependencies among key process parameters, such as laser power and scanning speed, affecting properties such as density and tensile strength. However, relying solely on experiential knowledge for process parameter design often hampers the precise attainment of target requirements. To address this challenge, we propose an innovative approach that integrates the analytic hierarchy process (AHP) and weighted particle swarm optimization (WPSO) to recommend SLM process parameters for high-temperature alloy fabrication.
View Article and Find Full Text PDFThe calcium ion (Ca) isa highly versatile intracellular signal messenger regulating many different cellular functions. It is important to design probes with good fluorescence and two-photon (TP) active cross-sections (Φ) to explore the concentration distribution of Ca. In this manuscript, a novel TP fluorescence calcium probe (BAPTAVP) with positive charges, based on the classical Ca indicator of BAPTA (1,2-bis(2-aminophenoxy)-ethane--tetra acetic acid), and a conjugated polymer (PCBMB) with negative charges were designed and synthesized.
View Article and Find Full Text PDFObjective: To introduce a new animal model of graded mechanical primary brainstem injury (BSI).
Methods: Altogether 45 rabbits were subjected to BSI by type II biological impact machine designed by the Third Military Medical University. The animals were divided into 4 experimental groups (n equal to 10) and 1 control group (n equal to 5) according to different magnitudes of impact pressure imposed on the occipital nodule: Group 1, 500-520 kPa; Group 2, 520-540 kPa; Group 3, 540-560 kPa; Group 4, 560-580 kPa and Group 5, 0 kPa with 20 kPa increase in each grade.