Publications by authors named "Xiao-Ying Qian"
A phytochemical investigation of the steroidal saponins from the rhizomes of var. led to the discovery and characterization of three new spirostanol saponins, papolatiosides A-C (-), and nine known compounds (-). Their structures were established via extensive spectroscopic data analysis and chemical methods.
View Article and Find Full Text PDFFour new polyhydroxylated steroidal saponins, parisverticillatosides A-D (-), together with four known spirostanol saponins () were isolated from the roots of . Their structures were elucidated on the basis of extensive spectroscopic analysis and chemical evidences. The discovery of the new compounds - extended the diversity and complexity of this spirostanol saponin family.
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- The study focuses on Paris polyphylla var. yunnanensis, a plant used in traditional Chinese medicine, aiming to isolate and identify its bioactive saponins.
- Researchers identified fourteen saponins, including seven new compounds, with Paris saponins VII (PSVII) exhibiting strong cytotoxicity against a specific pancreatic cancer cell line (BxPC-3) at low concentrations.
- Further analysis indicated that PSVII could inhibit cell growth and promote cell death through mechanisms involving apoptosis and pyroptosis by activating specific caspases.
The aim of the present study was to investigate whether metallothionein was involved in the protection of lung ischemic preconditioning (IP) against lung ischemia-reperfusion (I/R) injury. Adult male Sprague-Dawley rats were randomly divided into 3 groups based upon the intervention (n=8): control group (C), lung I/R group (I/R), lung I/R+IP group (IP). At the end of the experiment, the content of metallothionein was tested in lung tissue.
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