In recent years, due to the rise in the population and aging, the prevalence of neurological diseases is also increasing year by year. Among these patients with Parkinson's disease, stroke, cerebral palsy, and other neurological symptoms, dysarthria often appears. If these dysarthria patients are not quickly detected and treated, it is easy to cause difficulties in disease course management.
View Article and Find Full Text PDFAutophagy is a self-digestion process, wrapping cytoplasmic proteins or organelles to form vesicles for degradation in lysosomes. The process plays an important role in the maintenance of intracellular homostasis. Here we overview articles on autophagy and cancer/tumors in Pubmed and found 327 articles.
View Article and Find Full Text PDFObjective: To study the relationship between expression of p57KIP2 and prognosis and other clinicopathological parameters in invasive breast cancers.
Methods: We assessed the expression of p57KIP2 in 89 cases of invasive breast cancer and 20 cases of normal breast tissue by immunohistochemical methods and analyzed the results with SPSS software (ver. 16.
Zhejiang Da Xue Xue Bao Yi Xue Ban
September 2011
Objective: To generate a recombinant expression system of repeated serial antibiotic peptide Alloferon-1 DNA segment with trypsin digestion site and to determine its anti-tumor activity in vitro.
Methods: A 14 repeated serial DNA segment of Alloferon-1 with a lysine residual at the C-end that acts as the trypsin digestion site was constructed. pET42a vector and E.
Zhonghua Liu Xing Bing Xue Za Zhi
November 2009
Objective: To conduct serological investigation on H5N1/H9N2/H7N7 infection among people occupied in poultry fields.
Methods: Serum samples were collected from people working in live poultry and none-poultry retailing food markets, poultry wholesaling, large-scale poultry breading factories and in small-scale farms, wide birds breeding, swine slaughtering houses and from normal population. Antibodies of H5, H9 and H7 with hemagglutination inhibition and neutralization tests were tested and analyzed.