Publications by authors named "Xiao-Yi Pan"

Pulmonary Mucormycosis is a fatal infectious disease with high mortality rate. The occurrence of Mucormycosis is commonly related to the fungal virulence and the host's immunological defenses against pathogens. Mucormycosis infection and granulation tissue formation occurred in the upper airway was rarely reported.

View Article and Find Full Text PDF
Article Synopsis
  • A rare case of disseminated infection was reported in a 37-year-old male with recurrent fever, chest wall swelling, and vertebral destruction, likely due to poorly controlled diabetes and severe periodontal disease.
  • The diagnosis was confirmed through metagenomic next-generation sequencing (mNGS) from abscess drainage fluid.
  • Treatment involved systemic antibiotics and thoracic drainage, leading to significant improvement, underscoring the value of mNGS for accurate diagnosis and timely intervention.
View Article and Find Full Text PDF
Article Synopsis
  • Largemouth bass iridovirus (LMBV) poses significant threats to largemouth bass farming, resulting in high mortality and substantial economic losses, with no effective treatments available.
  • Researchers developed a recombinant version of the major capsid protein of LMBV and administered it orally to largemouth bass, measuring the resulting immune responses through various tests.
  • The study found that immunized fish exhibited significantly higher antibody levels and improved survival rates against LMBV, suggesting that the recombinant vaccine has strong potential to protect largemouth bass from this virus.
View Article and Find Full Text PDF

The hepatopancreas is an important digestive and immune organ in crustacean. There were low but stable numbers of microbes living in the hemolymph of crustacean, whereas the organs (including hepatopancreas) of crustacean were immersed in the hemolymph. It is very important to study the immune mechanism of the hepatopancreas against bacteria.

View Article and Find Full Text PDF

Antimicrobial peptides (AMPs), most of which are small proteins, are necessary for innate immunity against pathogens. Anti-lipopolysaccharide factor (ALF) with a conserved lipopolysaccharide binding domain (LBD) can bind to lipopolysaccharide (LPS) and neutralize LPS activity. The antibacterial mechanism of ALF, especially its role in bacteria, needs to be further investigated.

View Article and Find Full Text PDF

A facile synthesis approach of urchin-like and bouquet-like silver nanoparticles (AgNPs) using gas assisted wet chemistry method with silver nitride as source materials, ascorbic acid as reducing agent, polyvinylpyrrolidone (PVP) as passivator and NO₂/O₂ as ventilation mixture is proposed It was demonstrated that the urchin-like and bouquet-like AgNPs evolved from spherical nanoparti cles and/or clusters of Ag as a result of strong adsorption and passivation of newly-formed Ag {100} facets by PVP, which effectively boost preferential growth. The NO₂/O₂ as the ventilation mixture provides an equilibrium of aggregation and detachment of Ag atoms on the surface, thus confining the shapes of AgNPs generated. This study provides an alternative approach for synthesis AgNPs in specific shapes and facilitates their applications.

View Article and Find Full Text PDF

The frequent detection of paracetamol in natural water increased environmental concerns. The dielectric barrier discharge (DBD) technology is an effective paracetamol removing method, however, this research showed that the removal of paracetamol using DBD technology at 30 min dropped from 100% to 53.3% as the initial paracetamol concentration increased from 10 mg/L to 100 mg/L, due to the formation of more competitive intermediate products at higher paracetamol concentration.

View Article and Find Full Text PDF

Ichthyophthirius is a severe disease of farmed freshwater fish caused by the parasitic ciliate Ichthyophthirius multifiliis (Ich). This disease can lead to considerable economic loss, but the protein profiles in different developmental stages of the parasite remain unknown. In the present study, proteins from trophonts and theronts of Ich were identified by isobaric tags for relative and absolute quantitation (iTRAQ).

View Article and Find Full Text PDF

The parasite Ichthyophthirius multifiliis (Ich) has been reported in various freshwater fishes worldwide and results in severe losses to both food and aquarium fish production. Lactobacillus strains have a number of properties that make them attractive candidates as delivery vehicles for the presentation to the mucosa of compounds with pharmaceutical interest, in particular vaccines. Here, the present study was conducted to evaluate a live recombinant Lactococcus lactis vaccine expressing immobilization antigen (IAG-52X) in protection against I.

View Article and Find Full Text PDF

The present study was conducted to evaluate the in vitro and in vivo antiparasitic efficacy of active compounds from the bacterial extracellular products of Streptomyces griseus SDX-4 against Ichthyophthirius multifiliis. Bioassay-guided fractionation and isolation of compounds with antiparasitic activity were performed on n-butanol extract of S. griseus yielding a pure bioactive compound, nystatin (Nys), identified by comparing spectral data (EI-MS, (1)H NMR, and (13)C NMR) with literature values.

View Article and Find Full Text PDF

Ichthyophthirius multifiliis is a holotrichous protozoan that invades the gills and skin surfaces of fish and can cause morbidity and high mortality in most species of freshwater fish worldwide. The present study was undertaken to investigate the antiparasitic activity of crude extracts and pure compounds from the leaves of Macleaya microcarpa. The chloroform extract showed a promising antiparasitic activity against I.

View Article and Find Full Text PDF

Dactylogyrus intermedius is one of the most common and serious cause of parasitic diseases of freshwater fish in aquaculture, and can cause morbidity and high mortality in most species of freshwater fish worldwide. To attempt controlling this parasite and explore novel potential antiparasitic agents, the present study was designed to ascertain the anthelmintic activity of Chelidonium majus L. whole plant and to isolate and characterize the active constituents against D.

View Article and Find Full Text PDF

The ciliate Ichthyophthirius multifiliis is one of the most pathogenic parasites of fish maintained in captivity. In this study, effects of crude extracts, fractions, and compounds from the leaves of Macleaya cordata against I. multifiliis were investigated under in vitro conditions by bioactivity-guided isolation method.

View Article and Find Full Text PDF

Aim: To prepare the mAb against Vibrio harveyi and analyse their biological properties.

Methods: 8-week-old female BALB/c mice were immunized with pathogenic V.harveyi GYC1108-1, which was isolated from the diseased great yellow croaker in Zhejiang China in 2003.

View Article and Find Full Text PDF