Publications by authors named "Xiao-Xu Jin"

Article Synopsis
  • The study investigates factors contributing to erectile dysfunction (ED) in 150 male patients with localized prostate cancer (LPC) after they underwent radical surgery over a two-year period.
  • Results showed that a significant number (88 out of 150) experienced ED post-surgery, with factors like age, prostate size, comorbidities, and psychological state being key influences on this outcome.
  • The researchers conclude that better clinical interventions targeting these factors are essential to improve sexual function recovery and overall quality of life for LPC patients after treatment.
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Article Synopsis
  • The study aims to examine how consistent Gleason scores from preoperative biopsies are with postoperative pathology scores in prostate cancer patients and to develop a risk scoring model.
  • Researchers analyzed demographic and clinical data of patients who underwent radical prostatectomy and found significant differences in Gleason scores between biopsy and surgery results, highlighting factors like weight, BMI, and PSA levels.
  • They successfully created an 8-factor predictive model to assess the consistency of Gleason scores, showing its effectiveness through various statistical evaluations.
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Background: Oxaliplatin (Oxa) is the first-line chemotherapy drug for colorectal cancer (CRC), and Oxa resistance is crucial for treatment failure. Prostaglandin F synthase (PGF) (PGFS), an enzyme that catalyzes the production of PGF, is involved in the proliferation and growth of a variety of tumors. However, the role of PGFS in Oxa resistance in CRC remains unclear.

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Article Synopsis
  • - The study aimed to evaluate the effectiveness and safety of low-intensity extracorporeal shockwave therapy (Li-ESWT) in treating erectile dysfunction (ED) in 26 patients, administering treatments over six weeks while monitoring symptoms and side effects.
  • - Results showed significant improvements in IIEF-5 and EHS scores after the treatment, particularly peaking at six months, although some scores declined by the twelfth month but remained above baseline levels.
  • - The treatment had a low occurrence of adverse effects, mainly mild issues like itching and pain, indicating Li-ESWT is a promising option for improving ED symptoms safely.
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Objective: The study aimed to summarize the morphological characteristics of low-grade gastric intraepithelial neoplasia (LGIN) and explore its outcomes and risk factors. Additionally, it aimed to screen the core different expression genes (DEGs) of high-grade gastric intraepithelial neoplasia (HGIN) using bioinformatics methods to identify biomarkers for early gastric cancer outcomes.

Methods: The clinical and pathological data of 449 patients with LGIN in the endoscopy center of the Second Hospital of Hebei Medical University from June 2013 to September 2018 were collected for retrospective analysis.

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