Publications by authors named "Xiao-Xiao Jia"

Protective forests are the ecological barriers of oases in arid sand areas and can effectively prevent and control wind and sand hazards. The structural characteristics of individual trees, as the basic unit of protective forests, are the key factors affecting the protective benefits. With the typical leafless tree species of Ulan Buh Desert oasis, , var.

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We examined the growth decline and health status of farmland protective forest belt ( var and shelterbelts) in Ulanbuh Desert Oasis by using airborne hyperspectral and ground-based LiDAR to collect the hyperspectral images and point cloud data of the whole forest belt respectively. Through correlation analysis and stepwise regression analysis, we constructed the evaluation model of the decline degree of farmland protection forest with the spectral differential value, vegetation index, and forest structure parameters as independent variables and the tree canopy dead branch index of the field survey as dependent variables. We further tested the accuracy of the model.

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Background: Hyaluronic acid (HA) and HA fragments interact with a variety of human body receptors and are involved in the regulation of various physiological functions and leukocyte trafficking in the body. Accordingly, the development of an injectable HA fragment with good tissue permeability, the identification of its indications, and molecular mechanisms are of great significance for its clinical application. The previous studies showed that the clinical effects of injectable 35kDa B-HA result from B-HA binding to multiple receptors in different cells, tissues, and organs.

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Article Synopsis
  • * A proteomic analysis of psoriatic lesions revealed thousands of differentially expressed proteins over 12 weeks of treatment, indicating significant biological changes.
  • * Key proteins linked to treatment response were identified, and there was a positive correlation between specific protein levels and psoriasis severity, suggesting that blocking IL-17A and TNF-α impacts immune responses in psoriasis lesions.
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Airway remodeling is the main characteristic of asthma; however, the mechanisms underlying this pathophysiological change have not been fully elucidated. Previous studies have indicated that the Wnt/β-catenin and mitogen-activated protein kinase (MAPK) signaling pathway are involved in the development of airway remodeling during asthma. Therefore, the present study established an airway remodeling rat model, after which β-catenin, cyclin D1 and c-Myc protein expressions were analyzed via western blotting in the lung tissue and airway smooth muscle cells (ASMCs) of rats.

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Vitamin D exerts a protective role in asthma; however, the molecular mechanisms underlying the vitamin D-attenuated asthma airway remodeling are yet to be elucidated. In this study, Sprague-Dawley (SD) rats were randomly divided into four groups: control, asthma, vitamin D 50 ng/mL, and vitamin D 100 ng/mL. The treatment with 100 ng/mL vitamin D remarkably reduced the thickness of the airway smooth muscle, collagen deposition, and the alpha-smooth muscle actin (α-SMA) mass and airway inflammation.

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Melasma is a frequently acquired hyperpigmentary skin disorder, for which several therapies are available. Among them, 1064 nm QS Nd:YAG laser therapy is an effective method, but the recurrence rate of laser treatment is still high. The aim of the present study was to elucidate the mechanism of the high relapse rate of melasma after 1064 nm Nd:YAG laser treatment.

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Context: As a component of the outer membrane in Gram-negative bacteria, lipopolysaccharide (LPS)-induced proliferation and cell cycle progression of monocytes/macrophages. It has been suggested that the proapoptotic T-cell death-associated gene 51 (TDAG51) might be associated with cell proliferation and cell cycle progression; however, its role in the interaction between LPS and macrophages remains unclear.

Objective: We attempted to elucidate the role(s) of TDAG51 played in the interaction between LPS and macrophages.

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Objective: To establish Surface-enhanced Raman Spectroscopy (SERS) can be used as a rapid and reliable method to distinguish virulent strain and mild strain of L. pneumophila.

Methods: Mortality data were collected from company departments through administrative documents, death certificates, etc.

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Objective: To investigate the immune reconstitution by the transplantation of human umbilical cord blood CD34+ cells in the NOD/SCID mouse.

Methods: Mononuclear cells (MNC) were isolated from human fresh cord blood and CD34+ hematopoietic stem cells were selected by magnetic activated cell sorting method. The selected cells were transplanted via tail vein injection into 16 NOD/SCID mice after sublethal whole-body irradiation.

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