Publications by authors named "Xiao-Xiao Hao"

Article Synopsis
  • * Exposure to ACR leads to the upregulation of eEF2K, which is linked to learning and memory deficits, and manipulating eEF2K levels improved these cognitive issues in experiments.
  • * The findings suggest that eEF2K could be a promising target for clinical interventions aimed at countering ACR-related cognitive impairments by influencing lipid metabolism in the brain.
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Acrylamide is widely found in a variety of fried foods and cigarettes and is not only neurotoxic and carcinogenic, but also has many potential toxic effects. The current assessment of acrylamide intake through dietary questionnaires is confounded by a variety of factors, which poses limitations to safety assessment. In this review, we focus on the levels of AAMA, the urinary metabolite of acrylamide in humans, and its association with other diseases, and discuss the current research gaps in AAMA and the future needs.

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Article Synopsis
  • The study focuses on creating a model to predict how severe Alzheimer's disease might get by looking at changes in certain genes linked to a process called ferroptosis.
  • Researchers used data from a database and checked immune cells in samples to analyze differences between two groups.
  • They found several important genes that changed with increased levels of a substance called Aβ and believe this model will help doctors treat Alzheimer's disease better.
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Objective: To analyze the coagulation function and relevant factors of adults patients with acute lymphoblastic leukemia treated with pegasparase (PEG-ASP) or L-asaraginase (L-ASP).

Methods: The clinical features of 153 patients with acute lymphoblastic leukemia (ALL) received L-ASP or PEG-ASP in our hospital from January 2010 to January 2015 year were analyzed retrospectively. Among 153 patients, 108 patients received L-ASP treatment and 45 patients received PEG-ASP treatment.

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