Rapid Screening of 34 Emerging Contaminants in Surface Water by UHPLC-Q-TOF-MS.

Objectives: To establish a rapid screening method for 34 emerging contaminants in surface water by ultra-high performance liquid chromatography-quadrupole-time of flight mass spectrometry (UHPLC-Q-TOF-MS).

Methods: The pretreatment conditions of solid phase extraction (SPE) were optimized by orthogonal experimental design and the surface water samples were concentrated and extracted by Oasis HLB and Oasis MCX SPE columns in series. The extracts were separated by Kinetex EVO C18 column, with gradient elution of 0.