Publications by authors named "Xiao-Wen Zhan"
Article Synopsis
- The study focused on the effectiveness of using a combined blood purification method (haemoperfusion + continuous venovenous haemodiafiltration) to treat children with severe viral encephalitis, while also examining cerebrospinal fluid neopterin levels as a prognostic indicator.
- Researchers compared treatment outcomes among three groups of children: those receiving combined treatment, those receiving only CVVHDF, and those with mild encephalitis not treated with blood purification.
- Results showed that while there was no significant difference in some clinical outcomes, higher CSF neopterin levels were linked to more severe brain lesions and poorer motor functions, suggesting the potential for this blood purification method to improve treatment in severe cases
Background: To investigate the resistance-gene mutation of Mycoplasma pneumoniae (MP) in the bronchoalveolar lavage fluid of children with Mycoplasma pneumoniae pneumonia (MPP) and the clinical characteristics of refractory Mycoplasma pneumoniae pneumonia (RMPP) correlation.
Methods: Forty-eight children with MPP were selected and placed in RMPP and non-RMPP groups based on their clinical status - whether they had worsening clinical symptoms, persistent fever and a worsening lung image. They were also separated into drug-resistance gene mutation and non-mutated groups using nucleic acid detection.
A shortcoming of most correlation distance methods based on the composition vectors without alignment developed for phylogenetic analysis using complete genomes is that the "distances" are not proper distance metrics in the strict mathematical sense. In this paper we propose two new correlation-related distance metrics to replace the old one in our dynamical language approach. Four genome datasets are employed to evaluate the effects of this replacement from a biological point of view.
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