Publications by authors named "Xiao-Wei Xue"
Article Synopsis
- - Emerging research highlights the role of Epstein-Barr virus (EBV) in inflammatory bowel disease (IBD), indicating that immunosuppressive therapies may reactivate latent EBV, worsening patients' conditions.
- - A study analyzed colon specimens from 43 IBD patients to examine the clinical significance of latent EBV infection, finding significant differences in systolic pressure, disease variety, illness severity, and use of corticosteroids between EBV-positive and negative patients.
- - The findings suggest that IBD patients with latent EBV infection may experience more severe disease, warranting further investigation into EBV's role in IBD and careful monitoring of affected patients.
[Value of Thermal Tomography in Early Diagnosis of Breast Cancer in Animal Models].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
April 2020
To obtain ultrasound and thermal tomography images of breast cancer during its growth and to assess the value of thermal tomography in detecting breast cancer. Breast cancer models were established with NOD/SCID mice and SD rats. These animal models were examined by thermal tomography,plain ultrasound,and contrast-enhanced ultrasound.
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- The texture and stiffness of breast nodules are key factors in clinical examinations and ultrasound elastography, with malignant tissues typically being stiffer than benign ones.
- The exact mechanisms influencing breast nodule stiffness are still not fully understood but involve both the substances of the nodule and the surrounding mesenchyme, where collagen is a significant contributor.
- This review focuses on the molecular mechanisms behind the changes in intracellular and extracellular environments during the development of breast nodules.
In the present article, the authors introduce a newly-made rat holder device for easily inserting acupuncture needles into the acupoints at any parts of the body. This device is easy in operation and higher in applicability, being worthy of popularization for researchers engaging in experimental studies.
View Article and Find Full Text PDFA high fosfomycin resistance rate was observed in Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) in our previous study, but little is known about its mechanisms. In this study, we explored the prevalence of plasmid-mediated fosfomycin resistance determinants among fosfomycin-resistant KPC-KP strains from a Chinese university hospital and determined the complete sequence of a novel fosA3-carrying plasmid isolated from an epidemic K.
View Article and Find Full Text PDFAim: To investigate H2O2-induced promotion proliferation and malignant transformation in WB-F344 cells and anti-tumor effects of ursolic acid (UA) and oleanolic acid (OA).
Methods: WB-F344 cells were continuously exposed to 7 x 10(-7) mol/L H2O2 for 21 d. Observations of cell morphology, colony formation rates, flow cytometric analysis of cell cycle changes and aneuploidy formation indicated that H2O2 was able to induce malignant transformation of WB-F344 cells.
Because of its remarkable ability to acquire antibiotic resistance and to survive in nosocomial environments, Acinetobacter baumannii has become a significant nosocomial infectious agent worldwide. Tigecycline is one of the few therapeutic options for treating infections caused by A. baumannii isolates.
View Article and Find Full Text PDFAdenovirus transfection technique was used in the current study to show if thioredoxin-interacting protein (TXNIP) overexpression can induce cell apoptosis and injury in H9C2 cardiomyocytes cultured in normal glucose condition. And the mechanisms were then investigated. Briefly, H9C2 cardiomyocytes in logarithmic growth phase were randomly divided into three groups: normal cultured group, empty adenovirus vector group (Ad-eGFP) and TXNIP overexpression group (Ad-TXNIP-eGFP).
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