Protective effects of ten oligostilbenes from seeds on interleukin-1β-induced rabbit osteoarthritis chondrocytes.

Background: is an important traditional Chinese herb used to treat osteoarthritis (OA) and oligostilbenes are the main active ingredient of the seeds of . The monomer -resveratrol of this species was demonstrated to have chondroprotective effects as a lead compound for the treatment of osteoarthritis, but it has not been applied due to its low efficacy.

Methods: Oligostilbenes were isolated by chromatography and were identified by NMR and HPLC.