Publications by authors named "Xiao-Ru Ji"
Helmet Ventilation in a Child with COVID-19 and Acute Respiratory Distress Syndrome.
Case Rep Pediatr
September 2024
Background: In pediatric patients with severe COVID-19, if the respiratory support provided using high-flow nasal cannula (HFNC) becomes insufficient, no definitive evidence exists to support the escalation to noninvasive ventilation (NIV) or mechanical ventilation (MV). . A 9-year-old boy being treated with face mask-delivered biphasic positive airway pressure ventilation developed fever, tachypnea, and frequent desaturation.
View Article and Find Full Text PDFKunitz-type proteins or peptides have been found in many blood-sucking animals, but the identity of them in leeches remained elusive. In the present study, five Kunitz-type peptides named WPK1-WPK5 were identified from the leech . Recombinant WPK1-WPK5 were expressed in GS115, and their inhibitory activity against Factor XIa (FXIa) was tested.
View Article and Find Full Text PDFBackground: 5-Azacytidine (5-azaC) promotes the development of 'Kyoho' grape berry but the associated changes in gene expression have not been reported. In this study, we performed transcriptome analysis of grape berry at five developmental stages after 5-azaC treatment to elucidate the gene expression networks controlling berry ripening.
Results: The expression patterns of most genes across the time series were similar between the 5-azaC treatment and control groups.
Article Synopsis
- The study identifies 48 VvHSP20 genes in grapes, classifying them into 11 subfamilies based on genetic analysis, which highlights their structural similarities and evolutionary relationships.
- Most VvHSP20 genes lack introns or have only one, and they share a conserved domain that indicates they have distinct functions, including responses to various stresses and developmental processes.
- Analysis of gene expression showed that several VvHSP20s are down-regulated in response to hydrogen peroxide during fruit development, suggesting their involvement in grape berry maturation and hinting at functional differentiation among these genes.
Article Synopsis
- Riboflavin treatment accelerates the early ripening of 'Kyoho' grapes, although the specific molecular mechanisms were previously unclear.
- A study utilizing RNA sequencing (RNA-seq) revealed significant changes in gene expression, with 1526 genes up-regulated and 430 down-regulated after riboflavin treatment compared to the control.
- Analysis further indicated that this treatment affected genes linked to chlorophyll metabolism and photosynthesis, influencing growth and development while reducing oxidative stress and berry softening, leading to the early ripening of the fruit.