Association between serum neurofilament light chains and Life's Essential 8: A cross-sectional analysis.

Background And Aim: Serum neurofilament light chain (sNfL), a protein released into the bloodstream post-neuronal axonal damage, has been validated as a robust biomarker for a range of neurological and systemic diseases. Concurrently, Life's Essential 8 (LE8) comprises a holistic suite of health behaviors and metabolic markers that are essential for assessing and enhancing cardiovascular health. Nevertheless, the interrelation between LE8 and sNfL is not yet fully elucidated.

[Characteristics and Risk Assessment of Polycyclic Aromatic Hydrocarbons （PAHs） Contamination in Roadside Farmland Soils of China].

With the increasing development of transportation and the rise of motor vehicle ownership, the problem of polycyclic aromatic hydrocarbons （PAHs） pollution in roadside farmland soils cannot be ignored. This study examined the pollution levels, composition, sources, and health risks of PAHs in farmland soils along with highways in China, based on 16 years of soil data. The results indicated that the median concentration of 16 PAHs in China's roadside farmland soils was 490.

A new strategy of using periphyton to simultaneously promote remediation of PAHs-contaminated soil and production of safer crops.

Contaminated farmland leads to serious problems for human health through biomagnification in the soil-crop-human chain. In this paper, we have established a new soil remediation strategy using periphyton for the production of safer rice. Four representative polycyclic aromatic hydrocarbons (PAHs), including phenanthrene (Phe), pyrene (Pyr), benzo[b]fluoranthene (BbF), and benzo[a]pyrene (BaP), were chosen to generate artificially contaminated soil.

40 Hz auditory steady state response to linguistic features of stimuli during auditory hallucinations.

The auditory steady state response (ASSR) may reflect activity from different regions of the brain, depending on the modulation frequency used. In general, responses induced by low rates (≤40 Hz) emanate mostly from central structures of the brain, and responses from high rates (≥80 Hz) emanate mostly from the peripheral auditory nerve or brainstem structures. Besides, it was reported that the gamma band ASSR (30-90 Hz) played an important role in working memory, speech understanding and recognition.

Effects of polymorphisms in translesion DNA synthesis genes on lung cancer risk and prognosis in Chinese men.

Purpose: Translesion DNA synthesis (TLS) plays an important role in promoting replication through DNA lesions. Genetic polymorphisms in TLS genes may have potential roles in lung cancer development in humans.

Methods: We evaluated the association between genetic variants in six TLS genes and the risk and survival of lung cancer in a case-control study in China.

Expressions of thermostable bacterial cellulases in tobacco plant.

An economical method for the conversion of lignocellulosic biomass is to use plants as bioreactors for cellulases production. Two bacterial thermostable cellulases (E2 and E3) and a E3-E2 fusion form were expressed in tobacco, driven by a double 35S promoter and 5' TEV-UTL. The enzymes were targeted to the apoplast and cytosol via 5' signal peptides and 3' retention signal peptides, respectively, and all showed functional activities.

Phytase expression in transgenic soybeans: stable transformation with a vector-less construct.

A minimal linear gene cassette (35S-phytase gene-nos) with T-DNA borders was acquired by PCR and directly introduced into soybean through the pollen tube pathway. A total of 13% of T(1 )plants were positive for phyA by specific PCR. Southern blot analyses showed that phyA insertions were harbored stably in T(2) progeny.

[Neural engineering and neural prostheses].

The motivation of the brain-computer interface (BCI) research and its potential applications are introduced in this paper. Some of the problems in BCI-based medical device developments are also discussed.

Rapid amplification of 3' cDNA end of Suaeda liaotungensis betaine aldehyde dehydrogenase using one-step PCR.

Based on part of a known cDNA sequence of Suaeda liaotungensis betaine aldehyde dehydrogenase, we successfully cloned the 3' cDNA end of S. lianotungensis betaine aldehyde dehydrogenase using one-step PCR with a gene-specific primer and universal primer. Compared with the typical 3' RACE, one-step PCR is rapid, simple and inexpensive.

Molecular cloning and characterization of betaine aldehyde dehydrogenase gene from Suaeda liaotungensis and its use in improved tolerance to salinity in transgenic tobacco.

cDNA encoding betaine aldehyde dehydrogenase (BADH) from the halophyte Suaeda liaotungensis has been cloned, sequenced and expressed in tobacco (Nictiana tabacum 89). The full-length cDNA is 1506 base pairs (bp) long and encodes a 502 amino-acid polypeptide. The cDNA fragment coding for the mature enzyme was cloned into vector pCAMBIA-1301 for expression in tobacco.