Publications by authors named "Xiao-Qiao Wu"
Simultaneous detection of multiple microRNAs based on fluorescence resonance energy transfer under a single excitation wavelength.
Spectrochim Acta A Mol Biomol Spectrosc
December 2024
Article Synopsis
- * Traditional methods for detecting multiple miRNAs often require different excitation wavelengths, which complicates the process and signal acquisition.
- * This study introduces a new sensor capable of detecting multiple miRNAs simultaneously using a single excitation wavelength, achieving high sensitivity and specificity, and successfully identifying miRNAs in human serum samples, highlighting its clinical diagnostic potential.
Objective: To study the pathogenesis of viral myocarditis (VMC) and dilated cardiomyopathy (DCM) and their relationship.
Methods: Sixty samples including 20 VMC, 20 DCM and 20 controls were collected. The expression of Fas protein in myocardium of each group was detected by modified immunohistochemistry with unequivocal brown staining in the myocardial membrane scored as positive, and the results of positive reaction were analyzed by Ridit test.