Publications by authors named "Xiao-Ping Kong"
Objective: To understand the correlation of enterovirus 71 (EV71), P-selectin glycoprotein ligand-1 (PSGL-1), and scavenger receptor B2 (SCARB2) and to explore the possible pathway and mechanism of EV71 infection by observing the expression of EV71, PSGL-1 and SCARB2 in tissues of infants with brain stem encephalitis.
Methods: The organs and tissues of infants with EV71-VP1 positivity in their brain stems were chosen. Expression and distribution of EV71-VP1, PSGL-1, and SCARB2 were detected and compared by immunohistochemistry.
Article Synopsis
- The study aims to examine collagen fiber changes and osteopontin expression in the left ventricle of hypertrophic cardiomyopathy (HCM) cases, with a focus on potential forensic applications.
- The research includes 15 HCM cases, 15 cases of coronary heart disease, and 20 traffic accident cases to compare collagen volume and osteopontin levels using various staining and statistical methods.
- Findings show that both HCM and coronary heart disease groups had significantly higher collagen and osteopontin levels compared to the control group, suggesting these markers could help diagnose sudden deaths associated with HCM.
Objective: To explore the mechanism that how human enterovirus 71 (EV71) invades the brainstem and how intercellular adhesion molecules-1 (ICAM-1) participates by analyzing the expression and distribution of human EV71, and ICAM-1 in brainstem of infants with brain stem encephalitis.
Methods: Twenty-two brainstem of infants with brain stem encephalitis were collected as the experimental group and 10 brainstems of fatal congenital heart disease were selected as the control group. The sections with perivascular cuffings were selected to observe EV71-VP1 expression by immunohistochemistry method and ICAM-1 expression was detected for the sections with EV71-VP1 positive expression.
Objective: To improve the successful rate of operation and the livability in establishing acute myocardial ischemic rat model.
Methods: The successful rate of animal experiment is compared between traditional method and improved method.
Results: The successful rate of improved method was 90%, which was much higher than 30% in successful rate of traditional method.