Xinfuli Granule improves post-myocardial infarction ventricular remodeling and myocardial fibrosis in rats by regulating TGF-β/Smads signaling pathway.

Background: Recent clinical and experimental studies have confirmed the effects of Xinfuli Granule (XG), a compound Chinese medicine in the prevention and treatment of heart failure (HF). This study aimed to investigate the effects and the mechanisms of XG on ventricular reconstruction in rats with acute myocardial infarction (AMI).

Methods: Sprague-Dawley rats were subjected to left anterior descending branch ligation.

Xinfuli improves cardiac function, histopathological changes and attenuate cardiomyocyte apoptosis in rats with doxorubicin-induced cardiotoxicity.

Background: Xinfuli Granule (XG), a compound Chinese herbal medicine, has been effectively used in China for the treatment of heart failure for more than fifty years. This study aimed to investigate the effects and the underlying mechanisms of Xinfuli in rats with doxorubicin-induced cardiotoxicity.

Methods: Sprague-Dawley rats were treated with intraperitoneal injection of Doxorubicin (DOX, 2.

[Bonding interfaces of three kinds of cements and root canal dentin: a scanning electron microscope observation].

Objective: To compare the bonding properties of three kinds of cements by observing the bonding inteffaces of cements and root canal dentin.

Methods: 15 extracted mandibular premolars were divided into 3 groups, and were cemented by Rely X luting, Panavia F and Paracore 5 mL, respectively. Each tooth was sectioned into two parts and the dentin-cement interfaces at the coronal, middle and apical parts of the fiber post were oberved by scanning electron microscope (SEM).