[Characteristic of 8p11 Myeloproliferative Syndrome with Rare Phenotype].

Objective: To deeply understand the clinical manifestation, laboratory examination characteristics, diagnosis and treatment of an eight p11 myeloproliferative syndrome (EMS) with rare phenotypes.

Methods: The clinical and laboratory characteristics and the process of allogeneic hematopoietic stem cell transplantation (allo-HSCT) were summarized in 1 rare EMS case involving T/B/myeloid cells. Meanwhile, 2 similar cases in the previous literature were also discussed.

Differential expression of cytokeratin 14 and 18 in bladder cancer tumorigenesis.

It has been previously suggested that cytokeratins (CKs) are important diagnostic and prognostic biomarkers for urothelial lesions. Hence it is imperative to understand the expression pattern of cytokeratins during formation of papillary bladder cancer, which was the objective of the current study. Expression pattern of CK14 and CK18 were examined using immunohistochemical staining in a mice model of papillary bladder cancer.

Finite element analysis and design of cubic high-pressure anvils based on the principle of lateral support.

This article theoretically investigates the lateral support on cubic high-pressure anvil using finite element analysis. The results show that to gain the same chamber pressure, the value of system oil pressure can be decreased by reducing the lateral support area and the anvils' lifetime is extended when the lateral support area grows. The optimal lateral support area to maximize anvils' lifetime is 27.

[The clinical and experimental analyses of a multiple myeloma patient with derivative der(Y;1)].

Objective: To investigate the clinical significance of a rare chromosome abnormality der(Y)t(Y;1) in a patient with multiple myeloma (MM).

Methods: The chromosome spread was prepared after 24 h culture of bone marrow. G-banding technique was used to analyze the karyotype.

Hybrid-anvil: A suitable anvil for large volume cubic high pressure apparatus.

A hybrid-anvil used in cubic high pressure apparatus is presented, which makes it possible to pressurize samples of 36 mm(3) volume up to 5.5 GPa and to heat simultaneously up to 1350-1400 degrees C for routine operation. The hybrid-anvil has been designed based on the theory of multilayered pressure vessels and massive support, which can save weight about 60.

[Analysis of variant translocation der ins (17; 15) in patient with APL by G-banding technique and interphase fluorescence in situ hybridization].

To investigate the biological characteristics of the variant translocation der ins (17;15) in a patient with acute promyelocytic leukemia (APL), the conventional G-banding technique, interphase fluorescence in situ hybridization (int-FISH), RT-PCR, gene scanning, gene sequence and flow cytometry were performed. The results indicated that the variant translocation der ins (17, 15) observed by G banding technique was a rare type, the int-FISH assay by using dual-color pml/raralpha fusion probes confirmed the cytogenetic findings. The detection results of other molecular methods demonstrated the existence of the whole pml/raralpha fusion gene, while this case had insertion variant translocation.