Publications by authors named "Xiao-Peng Deng"

Background: In the past 3 years, the global pandemic of coronavirus disease 2019 (COVID-19) has posed a great threat to human life and safety. Among the causes of death in COVID-19 patients, combined or secondary bacterial infection is an important factor. As a special group, pregnant women experience varying degrees of change in their immune status, cardiopulmonary function, and anatomical structure during pregnancy, which puts them at higher risk of contracting COVID-19.

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Article Synopsis
  • The study compares the stigma associated with COVID-19 and mental disorders among adolescents and young adults in China, revealing that mental disorder-related stigma is notably higher (40.7%) than COVID-19-related stigma (17.2%).
  • Factors influencing stigma include gender, quarantine experience, education level, family income, and mental health symptoms, particularly PTSD for COVID-19 stigma and depression and anxiety for mental disorder stigma.
  • The findings suggest a need for tailored stigma-reduction interventions targeting either COVID-19 or mental disorders among youth.
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Background: Depression is a pervasive or persistent mental disorder that causes mood, cognitive and memory deficits. Uncaria rhynchophylla has been widely used to treat central nervous system diseases for a long history, although its efficacy and potential mechanism are still uncertain.

Purpose: The present study aimed to investigate anti-depression effect and potential mechanism of U.

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The roots of Euphorbia fischeriana known as "Langdu" in traditional Chinese medicine have been used for the treatment of tuberculosis in China. Through a bioactive phytochemical investigation of the roots of E. fischeriana, 15 diterpenoids were obtained by various chromatographic techniques.

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Background: This study aimed to explore the impacts of COVID-19 outbreak on mental health status in general population in different affected areas in China.

Methods: This was a comparative study including two groups of participants: (1) general population in an online survey in Ya'an and Jingzhou cities during the COVID-19 outbreak from 10-20 February 2020; and (2) matching general population selected from the mental health survey in Ya'an in 2019 (from January to May 2019). General Health Questionnaire (GHQ-12), Self-rating Anxiety Scale (SAS), and Self-rating Depression Scale (SDS) were used.

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One new indole diterpenoid, drechmerin I (), was isolated from the fermentation broth of sp. isolated from the root of . Its structure was elucidated based on 1 D and 2 D nuclear magnetic resonance (NMR), high resolution electrospray ionization mass spectrum (HRESIMS), and electronic circular dichroism (ECD) spectroscopic analyses as well as TD DFT calculations of ECD spectra.

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Electroactive biofilms play essential roles in determining the power output of microbial fuel cells (MFCs). To engineer the electroactive biofilm formation of Shewanella oneidensis MR-1, a model exoelectrogen, we herein heterologously overexpressed a c-di-GMP biosynthesis gene ydeH in S. oneidensis MR-1, constructing a mutant strain in which the expression of ydeH is under the control of IPTG-inducible promoter, and a strain in which ydeH is under the control of a constitutive promoter.

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Background: The hematopoietically expressed homeobox (HHEX) gene is an important determinant of mammalian heart development. This study aimed to identify the potential mutations of the gene in Chinese patients with congenital heart disease (CHD).

Methods: We collected 296 CHD patients and 200 controls, and classified the cardiac deformities.

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Objective: To investigate the value of spatiotemporal image correlation (STIC) technique in the ventricular septal defect diagnosis.

Methods: A total of 1,163 fetuses were enrolled in this study, diagnosed by fetal echocardiography and analyzed by STIC technique. We obtained effective STIC volumes from the fetus according to the Goncalves' report, and judged fetal cardiac structure from STIC volume information again with a double-blind method.

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