Publications by authors named "Xiao-Niao Chen"
Article Synopsis
- A study conducted on 122 myopic patients at Beijing Tongren Hospital aimed to assess the ocular surface's condition and its relation to myopia severity.
- Results showed that as axial length (AL) increased, the incidence and severity of dry eye also rose, with significant changes observed in various ocular parameters.
- The findings indicated that longer AL correlated with worse dry eye symptoms, shorter tear film break-up time, and more corneal staining, highlighting AL as a risk factor for dry eye in myopic individuals.
Acute kidney injury (AKI) is associated with damage to the nephrons and tubular epithelial cells (TECs), which can lead to chronic kidney disease and end-stage renal disease. Identifying new biomarkers before kidney dysfunction will offer crucial insight into preventive and therapeutic options for the treatment of AKI. Early growth response 1 (EGR1) has been found to be a pioneer transcription factor that can sequentially turn on/off key downstream genes to regulate whole-body regeneration processes in the leopard worm.
View Article and Find Full Text PDFPurpose: To report the long-term outcomes of Boston keratoprosthesis type I (B-KPro type I) implantation in the management of severe ocular surface disorders.
Methods: Retrospective case series. Patients who underwent B-KPro type I implantation at the People's Liberation Army General Hospital were enrolled between March 2011 and September 2019.
Aim: To investigate the protective effects of simvastatin (Sim) combined with nifedipine (Nif) on endothelial cells and elucidate the action mechanism.
Methods: Human umbilical vein endothelial cells (HUVEC) were used. mRNA and protein levels were measured by using reverse-transcription polymerase chain reaction (RT-PCR) and Western blotting, respectively.