Publications by authors named "Xiao-Ni Cai"
Article Synopsis
- Bacterial coinfections in marine animals, especially hybrid groupers, are often overlooked but have significant impacts on disease severity and mortality rates.
- A study conducted in Hainan Province found that infections with the bacterial strain GDH11385, combined with other pathogens, led to higher mortality (46.67%) compared to infections with GDH11385 alone (33.33%).
- The research suggests that certain organs in hybrid groupers are vulnerable to these coinfections, and that GDH11385 may exhibit specific patterns in how it expresses virulence genes during infection.
The stringent response mediated by the signal molecule (p)ppGpp is involved in response to multiple environmental stresses and control of various physiological processes. Studies have revealed that (p)ppGpp strongly affects the formation and maintenance of several bacterial biofilms. However, the specific regulatory roles of (p)ppGpp in biofilms, especially in the expression of genes related to cell motility and exopolysaccharides (EPSs) production, remain poorly understood.
View Article and Find Full Text PDFVibrio alginolyticus belongs to gram-negative opportunistic pathogen realm infecting humans and aquatic animals causing severe economic losses. The (p)ppGpp-mediated stringent response is corroborated to stress adaptation and virulence of pathogenic mechanisms. Limited reports are documented for the intricate assessment of (p)ppGpp synthetase genes in combating various stress adaptation and elucidation of virulence in V.
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