Publications by authors named "Xiao-Ming Tao"

The global solar market is booming with a rapid growth in installed integrated devices, while photovoltaic (PV) systems are suffering from waste heat, which causes the decline of the photovoltaic conversion efficiency (PCE). This study presents the seamless integration of the ionic thermoelectric generator (iTEG) layer with traditional PV modules, facilitating the exploitation of waste heat and augmenting the overall power output. Experimental results validate the effectiveness of the iTEG, demonstrating substantial power generation and a consistent energy output.

View Article and Find Full Text PDF

Introduction: This study compared the effectiveness of customized graduated elastic compression stockings (c-GECS) based on individual lower-leg parameter models with standard graduated elastic compression stockings (s-GECS) in patients with occupational edema (OE).

Methods: A single-blind, randomized controlled trial was conducted with 70 patients with OE, randomly assigned to the c-GECS or s-GECS group. Follow-up assessments were performed at 1 and 3 months.

View Article and Find Full Text PDF

Objective: To evaluate the diagnostic value of ultrasensitive C-reactive protein (hs-CRP) and homocysteine (Hcy) for cerebral infarction.

Methods: 260 elderly patients with cerebral infarction were recruited and assigned to the stroke group, and 60 healthy elderly were identified as controls and included in the normal group. Serum samples of all subjects were collected at the time of admission for the determination of hs-CRP and Hcy levels.

View Article and Find Full Text PDF

Objective: This study aimed to compare the efficacy of customized graduated elastic compression stockings (c-GECSs) based on lower leg parameter models with standard GECSs (s-GECSs) in patients with chronic venous disease (CVD).

Methods: In this randomized, single-blind, controlled trial, 79 patients with stage C2 or C3 CVD were assigned to one of two groups: c-GECSs or s-GECSs. The primary outcome was change to Venous Insufficiency Epidemiological and Economic Study Quality of Life (VEINES-QOL) scores at months 1, 3, and 6 as compared with baseline.

View Article and Find Full Text PDF

Humans rely increasingly on sensors to address grand challenges and to improve quality of life in the era of digitalization and big data. For ubiquitous sensing, flexible sensors are developed to overcome the limitations of conventional rigid counterparts. Despite rapid advancement in bench-side research over the last decade, the market adoption of flexible sensors remains limited.

View Article and Find Full Text PDF

Harvesting low-grade heat by an ionic hydrogel thermoelectric generator (ITEG) into useful electricity is promising to power flexible electronics. However, the poor environmental tolerance of the ionic hydrogel limits its application. Herein, we demonstrate an ITEG with high thermoelectric properties, as well as excellent capabilities of water retention, freezing resistance, and self-regeneration.

View Article and Find Full Text PDF

Synthetic materials and biomaterials with elastic moduli lower than 10 MPa are generally considered as soft materials. Research studies on soft materials have been boosted due to their intriguing features such as light-weight, low modulus, stretchability, and a diverse range of functions including sensing, actuating, insulating and transporting. They are ideal materials for applications in smart textiles, flexible devices and wearable electronics.

View Article and Find Full Text PDF
Article Synopsis
  • TCF7L2 is a transcription factor that plays a significant role in WNT signaling and is strongly linked to diabetes risk, potentially impacting pancreatic β-cell function via the PI3K/AKT pathway.
  • Researchers conducted experiments using MIN6 cells to understand how TCF7L2 affects this pathway, measuring key proteins and insulin secretion.
  • The study found that TCF7L2 inhibits the PIK3R1 gene's expression, which activates the PI3K/AKT pathway and boosts insulin release, emphasizing the importance of specific binding motifs for TCF7L2's function.
View Article and Find Full Text PDF

Physiological temperature varies temporally and spatially. Accurate and real-time detection of localized temperature changes in biological tissues regardless of large deformation is crucial to understand thermal principle of homeostasis, to assess sophisticated health conditions, and further to offer possibilities of building a smart healthcare and medical system. Additionally, continuous temperature mapping in flexible and stretchable formats opens up many other potential areas, such as artificially electronic skins and reflection of emotional changes.

View Article and Find Full Text PDF
Article Synopsis
  • This study aimed to explore how a specific gene variant, CDKAL1, contributes to the development of diabetic retinopathy (DR) in a Chinese population with type 2 diabetes.
  • Researchers conducted a case-control study involving 475 controls and 105 DR patients, genotyping them for the genetic variant rs10946398 using iPLEX technology.
  • The results showed that the C allele frequency of rs10946398 was significantly different between the control and DR groups, indicating that this genetic variant is linked to an increased risk of developing DR in patients with diabetes.
View Article and Find Full Text PDF

Background: Genome-wide association studies (GWAS) have reported that the polymorphism rs5219 of the potassium inwardly rectifying channel, subfamily J, member 11 (KCNJ11) is associated with type 2 diabetes mellitus (T2DM). Given that diabetic retinopathy (DR) is one of the most common microvascular complications of T2DM, GWAS have identified a number of potential susceptibility genes for DR. However, only a fraction of them have been replicated in different studies and show consistent genetic associations with the occurrence of DR.

View Article and Find Full Text PDF

The dissociation of carbon feedstock is a crucial step for understanding the mechanism of graphene chemical vapor deposition (CVD) growth. Using first-principles calculations, we performed a comprehensive theoretical study for the population of various active carbon species, including carbon monomers and various radicals, CHi (i = 1, 2, 3, 4), on four representative transition-metal surfaces, Cu(111), Ni(111), Ir(111) and Rh(111), under different experimental conditions. On the Cu surface, which is less active, the population of CH and C monomers at the subsurface is found to be very high and thus they are the most important precursors for graphene CVD growth.

View Article and Find Full Text PDF

This paper reports fabric circuit boards (FCBs), a new type of circuit boards, that are three-dimensionally deformable, highly stretchable, durable and washable ideally for wearable electronic applications. Fabricated by using computerized knitting technologies at ambient dry conditions, the resultant knitted FCBs exhibit outstanding electrical stability with less than 1% relative resistance change up to 300% strain in unidirectional tensile test or 150% membrane strain in three-dimensional ball punch test, extraordinary fatigue life of more than 1 000 000 loading cycles at 20% maximum strain, and satisfactory washing capability up to 30 times. To the best of our knowledge, the performance of new FCBs has far exceeded those of previously reported metal-coated elastomeric films or other organic materials in terms of changes in electrical resistance, stretchability, fatigue life and washing capability as well as permeability.

View Article and Find Full Text PDF

Background: Peroxisome proliferator-activated receptor gamma coactivator-1α (PPARGC1A/ PGC-1α) is a ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. The activity of PGC-1α or genetic variations in the gene encoding the enzyme may contribute to individual variations in mitochondrial function and insulin resistance or diabetes. The objective of this study was to assess the extent to which PPARGC1A (rs8192678) and serum uric acid (UA) and its interaction impact on T2DM susceptibility in Chinese Han population.

View Article and Find Full Text PDF

Background: The objective of this study was to systematically evaluate the contribution of the insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) to type 2 diabetes mellitus (T2DM) and its interaction with obesity to T2DM susceptibility.

Methods: To clarify whether IGF2BP2 is an independent risk factor for T2DM in Chinese population, we conducted a study with a total of 2,301 Chinese Han subjects, including 1,166 T2DM patients and 1,135 controls, for the genotype of a most common and widely studied polymorphism-rs4402960 of IGF2BP2. Genotyping was performed by iPLEX technology.

View Article and Find Full Text PDF

Fiber-based structures are highly desirable for wearable electronics that are expected to be light-weight, long-lasting, flexible, and conformable. Many fibrous structures have been manufactured by well-established lost-effective textile processing technologies, normally at ambient conditions. The advancement of nanotechnology has made it feasible to build electronic devices directly on the surface or inside of single fibers, which have typical thickness of several to tens microns.

View Article and Find Full Text PDF

Objective: To investigate the association between the NINJ2 gene rs11833579 polymorphism and stroke in Han Chinese population.

Methods: This study was a population-based cross-sectional case-control study. Polymerase chain reaction-restriction fragment length polymorphism (RFLP) and sequencing were used for the detection of NINJ2 genotypes in 790 patients with stroke (679 ischemic stroke) which were Han Chinese population from Fangshan First Hospital and 811 controls which were healthy Han Chinese population without family history of stroke in Fangshan district rural area.

View Article and Find Full Text PDF

Nanocomposites of chitosan and graphene oxide are prepared by simple self-assembly of both components in aqueous media. It is observed that graphene oxide is dispersed on a molecular scale in the chitosan matrix and some interactions occur between chitosan matrix and graphene oxide sheets. These are responsible for efficient load transfer between the nanofiller graphene and chitosan matrix.

View Article and Find Full Text PDF

A homologous set of 9,9-dialkyl-4,5-diazafluorene compounds were prepared by alkylation of 4,5-diazafluorene with the appropriate alkyl bromide and under basic conditions. The structures of these simple organic compounds were confirmed by spectroscopic techniques (FTIR, NMR, and FABMS). Their biological effects toward a panel of human carcinoma cells, including Hep3B hepatocellular carcinoma, MDAMB-231 breast carcinoma, and SKHep-1 hepatoma cells, were investigated; a structure-activity correlation was established with respect to the length of the alkyl chain and the fluorene ring structure.

View Article and Find Full Text PDF

A conductive polymer, poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS), was modified with dimethyl sulfoxide (DMSO) in solution state, together with sub-sequential thermal treatment of its spin-coated film. The electrical conductivity increased by more than three orders of magnitude improvement was achieved. The mechanism for the conductivity improvement was studied at nanoscale by particle size analysis, field emission scanning electron microscopy (FESEM), and X-ray photoelectron spectroscopy (XPS).

View Article and Find Full Text PDF

Flexible organic light-emitting diodes (FOLEDs) are facing mechanical issues arising from failure of the indium-tin oxide (ITO) films fabricated on flexible substrates. Polymeric nanocomposite anodes were fabricated by including single-wall carbon nanotubes (SWCNTs) in aqueous poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS). The conductivity, transmittance and flexibility of the polymeric nanocomposite anode were characterized.

View Article and Find Full Text PDF

We investigate new types of mode recouplings in a concatenated grating structure comprising a long-period grating and a fiber Bragg grating. It is demonstrated that the light coupled out to the cladding mode by one of these gratings can be recoupled back to the guided mode by the other grating. Theoretical analysis based on the coupled-mode theory is presented, together with experimental results.

View Article and Find Full Text PDF

A novel chitosan fiber core/gold shell structural organic-inorganic composite was presented via a facile and eco-friendly approach. The chitosan fiber and gold/chitosan composites were characterized with the assistance of scanning electron microscopy and transmission electron microscopy observations. The chitosan fibers used in this study were 50 nm to 5 microm in diameter and up to hundreds of micrometers in length.

View Article and Find Full Text PDF

Microencapsulated n-alkanes (n-octadecane, n-nonadecane, and n-eicosane) were synthesized by in situ polymerization using urea-melamine-formaldehyde polymer as shells. Microcapsules 5.0 and 10.

View Article and Find Full Text PDF