Publications by authors named "Xiao-Ling Zhao"

Article Synopsis
  • The study investigates the connection between Yang-deficiency constitution (YADC) and endometrial hyperplastic processes (EHPs), finding that YADC is more common in EHPs patients, which may indicate a higher risk for these conditions.
  • Analysis of gut microbiota from patients revealed that those with YADC showed greater inflammation and specific microbial signatures compared to non-YADC individuals.
  • The research suggests that certain interactions between gut microbiota and host genes may contribute significantly to the development of EHPs in individuals with YADC.
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Seawater and sea sand concrete (SWSSC) is an environmentally friendly alternative to ordinary Portland cement concrete for civil construction. However, the detrimental effect of high chloride content of SWSSC on the corrosion resistance of steel reinforcement is a concern. This study undertook the electrochemical corrosion behaviour and surface characterizations of a mild steel and two stainless steels (AISI type 304 and 316) in various simulated concrete environments, including the alkaline + chloride environment (i.

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Objective: This study explored the effects of sevoflurane exposure during different stages of pregnancy on the brain development of offspring.

Methods: Thirty-six pregnant SD rats were randomly divided into 4 groups: control, sevoflurane exposure in early (S1) pregnancy, sevoflurane exposure in middle (S2) pregnancy, and sevoflurane exposure in late (S3) pregnancy. After natural birth, the learning and memory capacity of offspring rats was analyzed using the Morris water maze experiment.

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This literature review has examined the use of FRP composite materials as a potential retrofitting technique for civil structures. Importantly, the various material properties, bond mechanisms, durability issues and fatigue resistance have been discussed. Studies exploring the performance of CFRP repaired steel have strongly indicated its potential as a rehabilitation material.

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The present study indicates the importance of using glass fiber reinforced polymer (GFRP) laminates with appropriate thickness and fibers orientation when exposed to harsh environmental conditions. The effect of different environmental conditions on tensile properties of different GFRP laminates is investigated. Laminates were exposed to three environmental conditions: (1) Freeze/thaw cycles without the presence of moisture, (2) freeze/thaw cycles with the presence of moisture and (3) UV radiation and water vapor condensation cycles.

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The antioxidant effect of salidroside has been proven, but its role in liver injury is poorly understood. In this study, we aimed to evaluate the protective effects and mechanism of salidroside on liver injury induced by carbon tetrachloride (CCl) in vivo. Mice were pretreated with salidroside (60 mg/kg, intraperitoneally injected, i.

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Carbon fiber reinforced polymer (CFRP) composites have exhibited a great potential for strengthening of steel structures. In the current study, an innovative prestressed unbonded reinforcement (PUR) system is introduced for fatigue strengthening of existing steel members. The system relies on a pair of mechanical clamps; each holds multiple CFRP plates and anchors their prestressing forces to the steel substrate via friction.

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Peroxisome proliferator activated receptor-alpha (PPARα) and Egl nine homolog 3 (EGLN3) play critical roles in facilitating the adaptation to a hypoxic environment. However, the relationship between EGLN3 and PPARα variants and hypoxic adaptation remains poorly understood in Tibetan chickens. To better understand the effects of genetic variation, we sequenced exons of PPARα and EGLN3 in 138 Lowland chickens (LC) from 7 breeds that were located in Emei, Miyi, Shimian, Wanyuan, Pengxian, and Muchuan in the Sichuan province, and Wenchang in the Hainan province (altitudes for these locations are below 1800 meters).

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In this research, bone marrow mesenchymal stem cells (BMSCs) were isolated from mouse, and induced differentiation into myocardial cells in vitro after overexpression of miR-1a. The results showed that the BMSCs could induce differentiation into myocardial cells under the special condition medium, but when the miR-1a was over-expressed in BMSCs, the differentiation efficiency and induction time of myocardial cells from BMSCs could be promoted. This reason was demonstrated that Delta-like 1 (Dll-1) was a transcriptional repressor of myocardium gene expression during myocardium differentiation, miR-1a reduced Dll-1 levels, leading to the accumulation of myocardium gene mRNA and a dramatic increase in myocardium gene protein.

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Article Synopsis
  • - The study investigates myogenic regulatory factors, which are key transcription factors that influence the development of skeletal muscle fibers, affecting the taste and texture of meat in Erlang Mountain Chickens.
  • - Researchers analyzed genetic variations in four genes (MyoD, Myf5, MyoG, and Mrf4) using a specific technique on 360 chickens raised in different housing systems (cage, pen, free-range).
  • - Results showed that specific genetic combinations (GG-TT and TT-CT) are linked to larger muscle fiber diameters, suggesting these genotypes could be useful genetic markers for improving meat quality in chicken breeding programs.
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In this experimental prospective study, we aimed to analyze the effect of transient scrotal hyperthermia on the male reproductive organs, from the perspective of sperm parameters, semen plasma biochemical markers, and oxidative stress, to evaluate whether different frequencies of heat exposure cause different degrees of damage to spermatogenesis. Two groups of volunteers (10 per group) received testicular warming in a 43°C water bath 10 times, for 30 min each time: group 1: 10 consecutive days; group 2: once every 3 days. Sperm parameters, epididymis and accessory sex gland function, semen plasma oxidative stress and serum sex hormones were tested before treatment and in the 16-week recovery period after treatment.

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CRBP1 (cellular retinol binding protein 1) and CRBP3 (cellular retinol binding protein 3), are important components of the retinoid signaling pathway and take part in vitamin A absorption, transport and metabolism. Based on the role of vitamin A in chicken laying performance, we investigated the polymorphism of CRBP1 and CRBP3 genes in 349 chickens using single strand conformation polymorphism and DNA sequencing methods. Only one polymorphism was identified in the third intron of CRBP1, two polymorphisms were detected in CRBP3; they were located in the second intron and the third intron respectively.

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In this study, the adsorption morphologies as well as stability and transitions of a commercial dispersant copolymer (BYK 9076) on the surface of multiwalled carbon nanotubes (MWCNTs) were studied using Fourier transform infrared and UV-vis spectroscopy, dynamic light scattering, and electron microscopy techniques. The results show that the dispersion of carbon nanotubes in ethanol does not increase continuously with increasing copolymer/CNT ratio, which is correlated with the adsorption morphologies of the copolymer on the CNT surface. At a ratio of copolymer/CNT below 0.

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TBC1D1 plays an important role in numerous fundamental physiological processes including muscle metabolism, regulation of whole body energy homeostasis and lipid metabolism. The objective of the present study was to identify single nucleotide polymorphisms (SNPs) in chicken TBC1D1 using 128 Erlang mountainous chickens and to determine if these SNPs are associated with carcass traits. The approach consisted of sequencing TBC1D1 using a panel of DNA from different individuals, revealing twenty-two SNPs.

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Article Synopsis
  • Researchers developed a nanocomposite material made of copper and low-density polyethylene (nano-Cu/LDPE) for possible use in intrauterine devices (IUDs).
  • The study evaluated how this material affects certain proteins (PAI-1, SP, and SP-R) in the uterine lining of different animal models over time, and compared its effects to those of bulk copper and LDPE.
  • Findings showed that nano-Cu/LDPE caused less damage to the endometrium compared to bulk copper, suggesting it could be a safer alternative for future IUD materials.
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Apolipoprotein B mRNA-editing enzyme catalytic subunit 2 (APOBEC2) plays an important role in regulating and maintaining muscle development in mammals. In this study, we evaluated APOBEC2 mRNA abundance and protein expression and the results indicated that APOBEC2 mRNA was most abundant in skeletal and cardiac muscle, with relatively low expression in the gonads, gizzard and subcutaneous fat tissues of chickens. Immunoreactive APOBEC2 was localized to the cell nucleus of developing myocardium and skeletal myofibers.

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Objective: To establish an effective and stable rabbit heat acclimatization model for the experiment of heat acclimatization mechanisms.

Methods: Sixteen healthy male rabbits were divided into heat acclimatization group and control group randomly (n = 8). Heat acclimatization (HA) group was kept in simulation chamber with dry bulb temperature of (36 +/- 1) degrees C, wet bulb temperature of (29 +/- 0.

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Objective: To develope a method of RSLC fingerprint analysis for the quality evaluation of Lycii Cortex, and assess the differences of Lycii Cortex from Lycium chinense and L. barbarum.

Methods: All separations were performed using a Rapid Separation Liquid Chromatography (RSLC) system with an Acquity UPLC C18 (2.

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The objective of this experiment was to evaluate the effect of dietary lysine concentration on meat quality and carcass traits in 2 chicken lines, SD02 and SD03, and their crosses, both originating from a Chinese native breed, the Erlang Mountainous chicken. The lines were selected for 4 generations by Sichuan Agricultural University (Ya'an, China); for the present study, chickens from the 2 lines and their crosses were randomly assigned at hatch to 1 of 2 dietary groups. One group was offered diets containing 1, 0.

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Acclimatization is a process of biological adaptation when exposed to environmental factors such as hypoxia, cold and heat for prolonged periods of time, where non-genetical variations play a role in allowing subjects to tolerate hypoxic, cold or hot environments. This review focuses on the characteristics and mechanisms of acclimatization found through major research advances by our institute. First, the mechanisms underlying the acclimatization to extreme environments are complex.

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The Mustang, Musculoskeletal Temporally Activated Novel-1 Gene (MUSTN1) plays an important role in regulating musculoskeletal development in mammals. We evaluated the developmental and tissue-specific regulation of MUSTN1 mRNA and protein abundance in Erlang Mountainous (EM) chickens. Results indicated that MUSTN1 mRNA/protein was expressed in most tissues with especially high expression in heart and skeletal muscle.

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Aims: Expression of Heat Shock Protein-27 (HSP27) is reduced in human coronary atherosclerosis. Over-expression of HSP27 is protective against the early formation of lesions in atherosclerosis-prone apoE(-/-) mice (apoE(-/-)HSP27(o/e)) - however, only in females. We now seek to determine if chronic HSP27 over-expression is protective in a model of advanced atherosclerosis in both male and female apoE(-/-) mice.

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Objective: To analyze the clinical features and brain, spinal cord magnetic resonance imaging (MRI) features of neuromyelitis optical (NMO) patients with positive anti-nuclear antibody serum (ANAs).

Methods: The clinical data of expanded disability status scale (EDSS) score, duration of the first relieving phase and first year recurrence-positive rate and MRI features of 34 NMO patients at our hospital during the period of 2006-2011 were retrospectively reviewed and divided into two groups according to the outcome of antibodies test:ANAs positive group (n=14) and ANAs negative group (n=20).

Results: (1) In the ANAs-positive group, the EDSS score of first NMO attack was (2.

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In plants, flowering as a crucial developmental event is highly regulated by both genetic programs and environmental signals. Genetic analysis of flowering time mutants is instrumental in dissecting the regulatory pathways of flowering induction. In this study, we isolated the OsLF gene by its association with the T-DNA insertion in the rice late flowering mutant named A654.

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The solute carrier family 27 (SLC27, also known as fatty acid transport proteins [FATPs]) plays important biological roles in cells. However, there is no report about the expression profile of SLC27 member in chicken. In this study, we quantified the expression of SLC27A1 (FATP1) mRNA in a mountainous black-boned chicken breed (MB) and a commercial meat type chicken breed (S01), to discern the tissue and age-related specific expression pattern and their potential involvement in fat deposition and muscle fatty acid metabolism.

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