Assessment of early anthracycline-induced cardiotoxicity and liver injury with T2 and T2* mapping in rabbit models.

Objectives: To evaluate the early prevalence of anthracycline-induced cardiotoxicity (AIC) and anthracycline-induced liver injury (AILI) using T2 and T2* mapping and to explore their correlations.

Materials And Methods: The study included 17 cardiotoxic rabbits that received weekly injections of doxorubicin and magnetic resonance imaging (MRI) every 2 weeks for 10 weeks. Cardiac function and T2 and T2* values were measured on each period.

Culture and identification of neonatal rat brain-derived neural stem cells.

Background: Timing of passaging, passage number, passaging approaches and methods for cell identification are critical factors influencing the quality of neural stem cells (NSCs) culture. How to effectively culture and identify NSCs is a continuous interest in NSCs study while these factors are comprehensively considered.

Aim: To establish a simplified and efficient method for culture and identification of neonatal rat brain-derived NSCs.

Biomimetic, Mechanically Strong Supramolecular Nanosystem Enabling Solvent Resistance, Reliable Fire Protection and Ultralong Fire Warning.

A graphene oxide (GO)-based smart fire alarm sensor (FAS) has gained rapidly increasing research interest in fire safety fields recently. However, it still remains a huge challenge to obtain desirable GO-based FAS materials with integrated performances of mechanical flexibility/robustness, harsh environment-tolerance, high-temperature resistance, and reliable fire warning and protection. In this work, based on bionic design, the supermolecule melamine diborate (M·2B) was combined with GO nanosheets to form supramolecular cross-linking nanosystems, and the corresponding GO-M·2B (GO/MB) hybrid papers with a nacre-like micro/nano structure were successfully fabricated a gel-dry method.

Meroterpene-Like α-Glucosidase Inhibitors Based on Biomimetic Reactions Starting from β-Caryophyllene.

Background: Natural meroterpenes derived from phloroglucinols and β-caryophyllene have shown high inhibitory activity against α-glucosidase or cancer cells, however, the chemical diversity of this type of skeletons in Nature is limited.

Methods: To expand the chemical space and explore their inhibitory activities against α-glucosidase (EC 3.2.

[Research progress on molecular genetics of forest musk deer].

Forest musk deer is one of the large-scale farming musk deer animals with the largest population at the same time. The male musk deer can secrete valuable medicines, which has high medicinal and economic value. Due to the loss of habitat and indiscriminate hunting, the numbers of wild population specie and the distribution have been drastically reduced.

[Research progress on musk secretion mechanism of forest musk deer].

Forest musk deer (Moschus berezovskii), a rare wild medicinal animal, is listed under the category of the state key protected wildlife list of China. Musk, secreted by the musk glands, is with high economic and medicinal value and used as precious traditional medicine in China. In order to meet the needs of musk in Chinese traditional medicine, forest musk deer farming was conducted in 1950s, but the research progress on musk secretion mechanism was slow.