Publications by authors named "Xiao-Jun Xi"
Chem Commun (Camb)
September 2022
Article Synopsis
- This study presents a fast method for identifying short-lived chemical intermediates produced during AC electrolysis using a combination of bipolar electrochemistry and nanoelectrospray ionization.
- The researchers successfully identified key reactive intermediates involved in the cross-metathesis reactions between 4-alkoxy anilines and alcohols.
- This work provides the first direct evidence supporting a previously proposed chemical mechanism in these reactions.
Epilepsy Behav
September 2020
Article Synopsis
- - This study investigates the higher risk of ADHD in children with epilepsy and seeks to understand the underlying molecular mechanisms linking the two disorders.
- - Researchers analyzed gene expression data to identify differentially expressed genes (DEGs) and used weighted gene co-expression network analysis (WGCNA) to find relevant genetic modules.
- - The findings highlight the Dlg4 and Vamp2 genes as key factors in the connection between epilepsy and ADHD, suggesting they contribute to the comorbidity of these conditions.
Article Synopsis
- Recurrent seizures in immature rats, induced by flurothyl inhalation, led to long-term neurodevelopmental issues, including reflex delays and difficulties in learning and memory.
- Administration of clonazepam decreased the expression of GABAR α1 and γ2 subunits and contributed to the delay in neurodevelopment, while flumazenil showed minimal effects.
- The study highlights the significance of GABAR α1 and γ2 subunits in the neurodevelopment of immature rats affected by recurrent seizures, suggesting potential targets for future treatments.
